Corbin Burnes struck out 11 batters and Gunnar Henderson smashed his majors-leading 15th home run as the Baltimore Orioles defeated the visiting Seattle Mariners 6-3 on Sunday afternoon.

Ryan O'Hearn also homered for the Orioles, who won two of three games in the series and completed an eight-game homestand with a 5-3 record. Cedric Mullins knocked in two runs, while Colton Cowser added three hits and scored twice.

Seattle's Luis Urias drove in two runs on a pair of hits and Luke Raley posted three hits.

Burnes (4-2) allowed one run on seven hits and one walk while matching his season-high strikeout total that was set in the season opener March 28.

Cole Irvin, making his first relief appearance of the season, threw two shutout innings and Craig Kimbrel, returning to a closer's role, worked a perfect ninth with two strikeouts for his ninth save.

Mariners starter George Kirby (4-4) took the loss in a six-inning stint. He was tagged for five runs and nine hits while striking out three.

Henderson homered on Kirby's fifth pitch to lead off the bottom of the first inning. The Orioles tacked on another run in the inning on Cowser's two-out infield single.

Urias singled in Raley from second to put the Mariners on the board in the second inning.

James McCann's run-scoring double in the bottom of the second pushed the Orioles to a 3-1 lead.

O'Hearn hit his sixth homer of the season to begin the third. Baltimore got another run in the inning after Cowser doubled and Mullins provided a two-out RBI single.

The Mariners scored two runs in the seventh inning in a bid to pull out a late-game comeback victory for the second day in a row. Urias doubled home a run before Julio Rodriguez came through with a run-scoring single with two outs.

Baltimore reliever Jacob Webb didn't record an out and was charged with two runs.

The Orioles added an insurance run on Mullins' run-scoring single in the eighth. Mullins turned in his first multi-hit game since April 21, a span of 19 games with one hit or fewer.