Indiana Pacers center Isaiah Jackson (Achilles) is done for the season after suffering an injury during Friday's game. Jackson suffered a torn right Achilles tendon which was a non-contact play during Friday's loss. Fellow big man James Wiseman (Achilles) suffered a season-ending injury on Opening Night. The Pacers have now lost two big men what seems like only a handful of games. That leaves Obi Toppin and Jarace Walker as the primary big men behind Myles Turner. Toppin hasn't been great this season, but is worth looking at with the Pacers extremely shorthanded now. He's averaging 10.7 points, 3.3 rebounds, and 1.7 assists across 20 minutes per game and his playing time is only going to increase now.

Portland Trail Blazers guard Anfernee Simons (arm) has been removed from the injury report ahead of Saturday's game against the Phoenix Suns. Simons fell on his arm during Friday's loss, but it seems like it was a minor issue. Simons appears to be fine and should play his normal workload on Saturday. He put together his worst performance of the season on Friday, but has been solid outside of that. Fantasy managers should go ahead and get him back in their lineups for this one.

Golden State Warriors forward Andrew Wiggins (back) is back in the starting five ahead of Saturday's game against the Houston Rockets. Wiggins will make his return to the court after missing each of the last two games due to a lower back strain. His return will push Lindy Waters III to the bench, which will certainly hurt his streaming value. The Warriors are without Stephen Curry (ankle) so Wiggins should be asked to do more on offense. Fantasy managers can go ahead and get Wiggins active in their lineups on Saturday.

Milwaukee Bucks forward Giannis Antetokounmpo (knee) has been cleared to play ahead of Saturday's game against the Cleveland Cavaliers. As expected, Antetokounmpo will play despite dealing with a knee issue. The Bucks continue to list him as probable, but Antetokounmpo has suited up every game this season. He has finished with a double-double every game with over 22 points in each of the first six games. Fantasy managers can go ahead and get Antetokounmpo active in their lineups.

Denver Nuggets guard Jamal Murray (concussion) has been ruled out ahead of Saturday's game against the Utah Jazz. This doesn't come as much of a shock after Murray was forced to exit early during Friday's game. He's currently in the league's concussion protocol, which could mean he misses a few games. The Nuggets haven't named the replacement for Murray, but Russell Westbrook figures to be the most likely candidate. Westbrook is a hit-or-miss type of fantasy players, but fantasy managers in need of help should look his way on Saturday.

Sacramento Kings forward Doug McDermott will move into the starting five ahead of Saturday's game against the Toronto Raptors. The veteran forward will get the starting nod with Kevin Huerter (illness) unable to play. Keon Ellis figured to get the start, but the Kings decided to go with McDermott. Normally, McDermott isn't a great fantasy option off the bench, but he could be more effective with extended run. He should be able to provide reliable shooting from beyond the arc.

Cleveland Cavaliers guard/forward Caris LeVert (knee) won't play in Saturday's game against the Milwaukee Bucks. LeVert is dealing with knee soreness. However, it's more likely he's getting a night off, considering he logged 22 minutes on Friday against the Orlando Magic. The 30-year-old has averaged 12.0 points and 4.3 assists this season. He's also shot an impressive 52.4% from behind the arc. With Max Strus (ankle) on the shelf, LeVert has been a vital piece of the Cavs rotation. But without him, Ty Jerome and Sam Merrill could benefit the most versus Milwaukee.

Toronto Raptors guard Immanuel Quickley (pelvis) won't play in Saturday's game against the Sacramento Kings. The former Knick is moving in the right direction, although he continues to deal with the residual effects of the hard fall he took in the opener. Davion Mitchell, averaging 9.0 points, 6.6 assists, and 2.4 rebounds in five starts this season, will continue to fill the void in the starting lineup. Mitchell should remain a viable fantasy streaming option for Saturday night. That may extend to Monday if Quickley isn't ready to get back on the floor.

Sacramento Kings guard Kevin Huerter (illness) won't play on Saturday in Toronto. The 26-year-old struggled in Friday's win over the Hawks, amassing 10 points and shooting 2-for-8 from behind the arc. He's under the weather, so his next chance to get back on the floor will be on Monday in Miami. But until then, Keon Ellis will likely slide into the starting lineup. Ellis averaged 8.8 points, 3.5 rebounds, and 1.7 while shooting 40.4% from deep in 21 starts last season, giving him some upside for fantasy managers in need of a streaming option.

Golden State Warriors guard Stephen Curry (ankle) remains out on Saturday versus the Houston Rockets. However, the multi-time All-Star is moving in the right direction. He participated in Saturday's shootaround, and the Warriors report he will be re-evaluated on Sunday. Curry has been out of the equation since suffering a sprained ankle in a recent matchup with the Los Angeles Clippers, keeping him off the floor for Golden State's previous two contests. It looks like Curry could be back soon. But until he returns, Brandin Podziemski, averaging 16.0 points, 6.0 assists, 5.5 rebounds, 1.0 blocks, and 1.0 steals in two appearances with the first five, is a must-start in all fantasy formats.

Utah Jazz forward Lauri Markkanen (back) won't play against the Nuggets on Saturday. The 27-year-old exited Tuesday's game versus the Kings and didn't suit up on Thursday against the visiting Spurs. He was listed as doubtful heading into this one. But now that Markkanen is officially sidelined, his next chance to suit up will be on Monday in Chicago. Kyle Filipowski, who got the start on Thursday, finished with 12 points, five rebounds, and one assist. Yet, since Jordan Clarkson (foot) is also sidelined, Filipowski could see more chances on the offensive end. He may also get more minutes.

Boston Celtics forward Jaylen Brown (hip) won't play on Saturday against Charlotte. The Celtics and Hornets met on Friday night, the first of back-to-back games between the clubs, with Brown finishing the night by scoring 25 points, adding six rebounds, five assists, one steal, and one block. He's bothered by a hip flexor strain, so fantasy managers will need to wait and see if he'll play on Monday in Atlanta. But without Brown in the mix on Saturday, Sam Hauser (back), who is probable, is expected to enter the starting lineup, giving him a more promising outlook in all fantasy setups.

Raptors' G Gradey Dick scored 31 points on 13-of-26 shooting in a 125-131 loss to the Lakers on Friday, Nov. 1. Dick is owned in only 15.4% leagues.

Golden State Warriors guard De'Anthony Melton (back) won't play on Saturday against Houston due to inflammation in his lower back. It will be the third consecutive game he will miss. Melton has played in three games this season after he was limited to 38 contests with the 76ers last season because of a back injury. WithStephen Curry(ankle) also out Saturday, Lindy Waters and Moses Moody will likely see more action.

Utah Jazz guard Jordan Clarkson (foot) was diagnosed with left plantar fasciitis. He will be re-evaluated in one week. Utah's injury report continues to grow heading into Saturday's matchup with the Denver Nuggets, with Lauri Markkanen (back) listed as doubtful. Collin Sexton (finger) also suffered an avulsion fracture in Thursday's game against the Spurs, although he will continue to play "as tolerated." Without Markkanen and Clarkson on the floor, Utah will rely on Sexton, John Collins, and Keyonte George primarily on the offensive end. As a result, all three players could exceed expectations while Markkanen and Clarkson are sidelined.

Washington Wizards forward Kyle Kuzma (groin) won't play on Saturday versus the Heat. This will mark the veteran's second consecutive absence because of a groin strain suffered in Monday's game against Atlanta. Kyshawn George entered the starting lineup for Wednesday's win over the Atlanta Hawks, the second of back-to-back games with the club, finishing with 11 points, four assists, and three steals. While George still has a lot to prove, he's worth monitoring in case he continues to play well. But as far as Saturday's contest is concerned, Bilal Coulibaly and Jordan Poole are the players anticipated to benefit the most from Kuzma's absence. Corey Kispert, coming off a 16-point showing on Wednesday, can also be added to fantasy lineups.

Denver Nuggets guard Jamal Murray (concussion) won't return to Friday's game against the Minnesota Timberwolves. He struggled throughout the contest, amassing only six points while shooting 2-for-7 from the field (0-for-3 from deep). Unfortunately, a collision with Julius Randle landed Murray in concussion protocol, ending his night abruptly. The 27-year-old has an extensive injury history, meaning the Nuggets will likely play it safe even if further testing brings positive results. As a result, Murray probably won't be out there for Saturday's game against the Jazz, likely resulting in Russell Westbrook sliding into the starting lineup.

Milwaukee Bucks forward Giannis Antetokounmpo (knee) is probable heading into Saturday's game against the Cavaliers. The multi-time All-Star has carried an injury designation for right patella tendinitis before all of Milwaukee's games this season. However, the ailment hasn't kept him off the floor. Antetokounmpo has averaged 30.4 point, 11.6 rebounds, and 5.8 assists. Yet, he hasn't made a shot from deep. Fortunately, the 29-year-old has shot a career-high 65.6% from the field, so that will help lessen the blow for category managers.

New York Knicks forward Karl-Anthony Towns is available and starting for the Knicks on Friday in their matchup against the Detroit Pistons. Towns was originally listed as questionable with a wrist injury but will be able to play through the pain. The 28-year-old will have a tough matchup against the Pistons who have been strong defensively against forwards. Towns has been sporadic in his offensive production so far, posting up point totals of 12, 21, 13 and 44 on the season. He's providing much more consistency from a rebounding perspective, averaging 11.3 RPG. Fantasy managers will certainly still want him in their starting lineups no matter what. DFS managers may want to take caution with adding him in their lineups given the volatility of tonight's matchup.

Golden State Warriors guard Stephen Curry (ankle) is ruled out for Saturday's matchup with the Houston Rockets. Curry will miss his third game in a row due to a left ankle strain he suffered against the Clippers on Sunday. Given that it is so early in the season, the Warriors are likely not rushing the 36-year-old back. With the sharpshooter out, Brandin Podziemski could see more playing time, or Andrew Wiggins (back), who is probable for Saturday's contest.