Athletics shortstop Jacob Wilson is not in the team's starting lineup for Wednesday's game against the Chicago White Sox in Chicago. Rookie Max Muncy will take his place at shortstop and will hit ninth against White Sox right-hander Jonathan Cannon. This will be Wilson's first day off of the 2025 season. The 23-year-old prospect and former sixth overall pick in 2023 out of Grand Canyon University has lived up to expectations so far this and entered Wednesday's action slashing .333/.333/.485 with an .818 OPS, two homers, eight RBI and 11 runs scored for fantasy managers. Expect him to be back in the lineup for Thursday's series finale against the White Sox. Muncy, another first-rounder, has been a bit overmatched at the plate in his first 16 MLB games, going 10-for-54 (.185) with a homer, four doubles, four RBI, on walk and 16 strikeouts. He should be avoided as a DFS play in the nine-hole.

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Los Angeles Angels catcher Logan O'Hoppe (finger) will be out of the starting lineup for the second straight day on the road in Texas against the division-rival Rangers on Wednesday. O'Hoppe began to feel ill during an off day on Monday and will miss the first two games of the series at Globe Life Field. There's a good chance he'll be back behind the dish for Thursday's series finale against the Rangers. The 25-year-old backstop has been a must-start catcher in fantasy in the early going, batting .333 (16-for-48) with five home runs, nine RBI and seven runs scored in his first 13 games of 2025. Travis d'Arnaud will do the catching again on Wednesday and will hit fifth against Rangers left-hander Patrick Corbin. Although d'Arnaud has gone just 2-for-22 at the plate this year, he's worth a look in DFS thanks to a .444 career average against Corbin in 18 at-bats.

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Tampa Bay Rays first baseman Jonathan Aranda and second baseman Brandon Lowe will both start on the bench against a left-hander on Wednesday against the division-rival Boston Red Sox. Curtis Mead will make the start at first base and will bat second, while Coco Montes is starting at second and hitting seventh against Red Sox left-hander Sean Newcomb. Aranda is hitting a strong .414 (19-for-46) on the year with three home runs, 11 RBI and 10 runs scored, but the Mexican slugger has yet to start in 2025 against a southpaw. Lowe has only made one start this year against a lefty, and like Aranda, he also has three home runs on the season in 61 at-bats. Mead has DFS upside as a deep sleeper in the two-hole on Wednesday, but he's gone just 4-for-22 in the early going for Tampa with an RBI and a run scored. Still, he's the better DFS sleeper option than Montes.

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Baltimore Orioles left-hander Trevor Rogers (knee) will face live hitters in Sarasota, Fla., next week and could return from the 15-day injured list before the end of May, according to general manager Mike Elias. Rogers is working his way back from a subluxation of his right knee and might not be far off from going on a minor-league rehab assignment. The 27-year-old southpaw, who was a former 13th overall pick by the Miami Marlins in 2017, was acquired in a trade with Miami last year to bolster Baltimore's starting rotation. The former All-Star was a disaster in his four starts for the O's, though, going 0-2 with a 7.11 ERA and 1.84 WHIP in 19 innings, and was eventually sent to the minors. With minor-league options remaining, there's no guarantee that Rogers will rejoin the team's big-league starting rotation when he's recovered from his knee injury.

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Boston Red Sox rookie second baseman Kristian Campbell is taking the day off for Wednesday's contest against the division-rival Tampa Bay Rays at George M. Steinbrenner Field. He will be replaced at second base by David Hamilton, who will hit eighth against struggling Rays right-hander Zack Littell. Campbell will get a breather after starting each of the team's last eight games. One of the team's top prospects coming into the year, the 22-year-old earned an Opening Day roster spot as the starting second baseman and has not disappointed in his first 18 games, hitting .302/.392/.508 with a .900 OPS, three homers, four RBI, six RBI, a steal, 11 runs scored, 10 walks and 18 strikeouts. He should be back in there after an off day on Thursday in Friday's series opener against the Chicago White Sox. Hamilton offers very little offensive upside at the bottom of the batting order and has just one hit in 21 at-bats this year.

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Baltimore Orioles right-hander Tyler Wells (elbow) will begin to throw off a mound within the next two weeks, according to general manager Mike Elias. Barring a setback while recovering from a UCL repair, Wells could return in the latter half of the summer. Wells had a UCL revision and an internal-brace procedure last June, which will keep him out until at least the second half of the season. For that reason, he should remain on the waiver wire in most fantasy leagues for most, if not all, of 2025. The 30-year-old former 15th-round pick by the Minnesota Twins in 2016 out of California State University -- San Bernardino only made three starts before being shut down last year, so he'll most likely have a limited workload whenever he returns. He had a career-best 3.64 ERA, 0.99 WHIP and 117:34 K:BB in 118 2/3 innings with the O's in 2023.

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Baltimore Orioles right-handed reliever Andrew Kittredge's (knee) recovery from left-knee surgery is "flying along," according to general manager Mike Elias. Kittredge will throw live batting practice the week after next before going on a minor-league rehab assignment. Barring a setback along the way, the 35-year-old veteran could return from the injured list before the end of May. Kittredge threw his first bullpen session over the weekend after having arthroscopic knee surgery. It sounds like he is recovery very nicely, but he might still be over a month away from making his debut with the Orioles. When healthy, Kittredge figures to be in the mix as a high-leverage, late-inning bullpen arm for the O's. He was an All-Star in 2021 and had a 2.80 ERA, 1.13 WHIP and one save in 70 2/3 innings with the St. Louis Cardinals a year ago. He hasn't had an ERA over 3.15 since 2019 and also sports 16 career saves.

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Baltimore Orioles right-hander Kyle Bradish's (elbow) recovery from Tommy John surgery is "flying along" as well as it could be, according to general manager Mike Elias. Bradish is right on track in his recovery and could return in the later half of the summer. The 28-year-old threw his first bullpen session last Saturday since he had TJ surgery last June. While he had an ERA under 3.00 in each of the last two seasons, he only made eight starts in 2024 before being shut down with elbow issues before needing elbow reconstruction. When Bradish does return, he'll have his innings managed, which will lower his fantasy ceiling. For now, he should remain on the waiver wire in most single-year fantasy leagues. In 30 starts in his second MLB season in 2023, Bradish went 12-7 with a 2.83 ERA and 1.04 WHIP with 168 strikeouts and 44 walks in 168 2/3 frames over 30 starts.

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Baltimore Orioles right-hander Grayson Rodriguez (elbow) will throw his third bullpen session on Thursday, according to MLB.com's Jake Rill. There's still no timetable for his return, though, as there is "a lot ahead" in his recovery. The 25-year-old is progressing in his recovery from right-elbow inflammation that cropped up during spring training, but he has yet to suffer a setback. He will need to start facing live hitters next before eventually being cleared to go on a minor-league rehab assignment. Because Baltimore won't rush Rodriguez to make his 2025 debut, fantasy managers probably shouldn't expect him to return until early May in a best-case scenario. The former first-rounder was shut down early last year due to a lat strain but was solid before that in his second MLB season, going 13-4 with a 3.86 ERA and 1.24 WHIP with 130 K's and 36 walks in 20 starts. Stash Rodriguez in all fantasy formats.

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Baltimore Orioles outfielder Tyler O'Neill (neck) has been scratched from Wednesday's starting lineup against the visiting Cleveland Guardians due to neck discomfort, according to The Baltimore Banner's Andy Kostka. Ramon Laureano will replace O'Neill in left field and hit ninth in the batting order against Guardians right-hander Gavin Williams. O'Neill, who has missed his fair share of time due to injuries in his career, should be considered day-to-day for now, but don't be surprised if he misses additional time. The O's wrap up their series against Cleveland on Thursday before starting a new weekend series on Friday against the visiting Cincinnati Reds. Laureano should be considered a long shot to return much DFS value in the nine-hole. He's gone 1-for-13 so far this year and has gone hitless in three career at-bats against Williams.

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Baltimore Orioles right-hander Zach Eflin (lat) played catch on Wednesday for the first time and is optimistic and hopes to return to the team soon. "I'm not interested in missing a lot of time," Eflin said. The 31-year-old's right-lat strain has been considered "very mild," and his timetable for a return will ideally be measured in "weeks than months." He will eventually go on a minor-league rehab assignment before returning from the injured list, so there's a chance we won't see Eflin again until the beginning of May. The former first-rounder was looking good in his first three starts in his first full season with Baltimore before his injury, going 2-1 with a 3.00 ERA and 0.83 WHIP with eight strikeouts and only one walk in 18 innings pitched. Eflin is a control artist, but his lack of strikeouts last year and to start this year is a bit concerning.

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Cleveland Guardians outfielder Lane Thomas (wrist) is finally returning to the starting lineup on Wednesday against the Baltimore Orioles and right-hander Dean Kremer at Camden Yards for the first time since April 8. Thomas will start in center field and bat fifth in the lineup. The 29-year-old missed the last six games due to a bruised right wrist from a hit-by-pitch in the team's home opener. Fantasy managers may want to keep Thomas on the bench, as he has started the 2025 season going just 5-for-31 (.161) with no home runs, two RBI and one stolen base in nine games played. He's also hit just .111 in a small sample size of nine career at-bats against Kremer. Angel Martinez has shifted to right field and is batting sixth on Wednesday, with both Nolan Jones and Jhonkensy Noel starting on the bench for Cleveland.

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Pittsburgh Pirates catcher Joey Bart (back) remains out of the starting lineup for Wednesday's contest against the visiting Washington Nationals at PNC Park. It's the fifth straight missed game after he came down with lower-back soreness late last week. With Endy Rodriguez (finger) landing on the injured list on Tuesday, Henry Davis will make another start behind the plate to catch left-hander Bailey Falter while batting ninth against Nationals left-hander Mitchell Parker. The Bucs finish their series with the Nats on Thursday, but if Bart isn't ready for Friday's series opener in Pittsburgh against the Cleveland Guardians, he may land on the injured list. Davis, the former first overall pick in 2021 out of Louisville, has struggled to find his footing offensively in the big leagues and has gone 2-for-13 so far in 2025. He'll be a poor DFS play on Wednesday and has never faced Parker in his career.

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The Boston Red Sox placed third baseman Alex Bregman on the paternity list on Wednesday and recalled infielder/outfielder Nick Sogard from Triple-A Worcester in a corresponding move. Bregman put on a show in Tuesday's win over the division-rival Tampa Bay Rays on Tuesday, going 5-for-5 with two home runs, a double, four RBI and two runs scored, but now he'll miss the series finale in Tampa and potentially the entire weekend series against the Chicago White Sox. The 31-year-old two-time All-Star has so far enjoyed his time in Beantown, as he's slashing .321/.365/.564 with a .929 OPS, four home runs, a league-high seven doubles, a league-high 25 hits, 16 RBI, a stolen base and 10 runs scored in a league-high 78 at-bats. With Bregman out of the lineup on Thursday against the Rays, Romy Gonzalez will fill in at the hot corner and bat fifth against right-hander Zack Littell.

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Los Angeles Dodgers left-hander Clayton Kershaw (knee, toe) had a positive first minor-league rehab start on Wednesday with Triple-A Oklahoma City, throwing three scoreless innings while allowing two hits, walking none and striking out two. The 37-year-old former MVP and three-time Cy Young winner threw 22 of his 30 pitches for strikes but only topped out at 88.8 mph with his four-seam fastball. Kershaw has plenty of time to build his velocity back up, though, as he's not eligible to come off the 60-day injured list until May 17. The Dodgers are going to take their time with the future Hall of Famer, which means he might not even be allowed to rejoin their big-league starting rotation by May 17. While Kershaw can still have solid outings, he has become much more of a fantasy dice roll and is likely to have his innings heavily managed when he eventually returns.

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If New York Mets right-hander Griffin Canning (illness) isn't able to make his next start in one of the next few days, New York Newsday's Tim Healey suggests that the Mets could call up pitching prospect Brandon Sproat to make his major-league debut. Sproat is considered the Mets' top prospect, per MLB Pipeline, and he's coming off his best outing at Triple-A Syracuse in which he allowed just one run on two hits in 4 1/3 innings last Saturday. The 24-year-old got off to a rough start on the farm, though, and currently holds a 5.23 ERA, 1.26 WHIP and 11:7 K:BB in 10 1/3 innings over three starts. Last year in 116 1/3 frames, he held a 3.40 ERA and 1.11 WHIP with 131 K's and 42 walks at three different minor-league levels. The Mets start a four-game series against the St. Louis Cardinals on Thursday. If Sproat does make a spot start on Friday, it could just be a one-game audition before he heads back to the minors.

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Los Angeles Angels shortstop Zach Neto (shoulder) went 2-for-5 with his fourth home run at Triple-A Salt Lake on Tuesday night while playing the whole game at shortstop. Neto is scheduled to play another full game at the 6 on Wednesday and could then be activated from the 10-day injured list as early as Thursday. However, the Orange County Register's Jeff Fletcher wouldn't be surprised if the Angels wait to bring Neto back until next Tuesday. The Halos wrap up their series in Texas against the division-rival Rangers on Thursday before heading home on Friday for a weekend series against the San Francisco Giants. At the latest, he'll make his season debut on Tuesday against the Pittsburgh Pirates. The former first-rounder has gone 13-for-45 (.289) in his 12 rehab games with the Bees and will be the Angels' starting shortstop when he's ready after hitting 23 homers and stealing 30 bases in 2024.

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Philadelphia Phillies designated hitter Kyle Schwarber is making the start in left field and will bat third for the Phillies on Wednesday against the visiting San Francisco Giants and left-hander Robbie Ray at Citizens Bank Park. Schwarber made only five starts in the outfield last year, and this will be his first start in the outfield in 2025. The 32-year-old left-handed slugger has had a strong start to his fourth season in Philadelphia, as he enters Wednesday's contest slashing .267/.421/.617 with a 1.038 OPS, a league-leading six home runs, a double, triple, 12 RBI, a stolen base and 15 runs scored in his first 17 games played. Fantasy managers shouldn't be getting their hopes up that Schwarbs will suddenly regain outfield eligibility this year. In DFS contests, fantasy managers will probably want to avoid the power threat against a tough lefty. Schwarber is hitless in four career at-bats against Ray.

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The St. Louis Cardinals are hoping that catcher Ivan Herrera (knee) can begin running and catching this weekend, according to manager Oliver Marmol. If Herrera can progress to that point this weekend, it will give the team a better indication on when he might be able to return from the injured list. Marmol also said that Herrera is progressing to hitting in the batting cages and playing catch. The 24-year-old backstop will not travel with the team to New York this weekend. It was announced last week that Herrera was expected to miss around four weeks after suffering a bone bruise in his left knee. Fantasy managers will want to stash him in an IL spot until he returns after he hit .381 (8-for-21) with four homers (three in one game), 11 RBI and six runs scored in his first seven games as the starting catcher. Until he's back, Pedro Pages will function as the starter with Yohel Pozo backing him up.

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Chicago Cubs catcher Carson Kelly (hand) is back behind the dish to catch left-hander Matthew Boyd in Wednesday's series finale against the San Diego Padres at Petco Park. Kelly will hit eighth in the batting order against Padres right-hander Nick Pivetta after missing the first two games of the series in SD due to a left-hander injury that he suffered when he was hit by a pitch on Sunday against the Los Angeles Dodgers. With Kelly returning, Miguel Amaya will head to the bench. The 30-year-old veteran has had a phenomenal start to his first season with the Cubbies, going 10-for-24 (.417) with four home runs and 13 RBI in nine games played. Kelly isn't going to be this good all year long as he shares playing time with Amaya, but fantasy managers are riding his hot streak early on. He has two hits and an RBI in just four career at-bats against Pivetta.

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