According to NFL Media's Ian Rapoport, San Francisco 49ers running back Christian McCaffrey (Achilles) will make his 2024-25 debut on Sunday against the Bucs. The 28-year-old hasn't played all season while dealing with bilateral Achilles injuries. But fantasy managers will finally get him back in Week 10. Although there's a chance he could see fewer snaps than usual, there's no way anyone should keep him out of their fantasy lineups. McCaffrey's expected return will cause Jordan Mason's fantasy ceiling to come crashing down. Still, Mason is worth holding on to for insurance purposes, considering McCaffrey has had issues staying off the injury report over the years.

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According to NFL Media's Ian Rapoport and Tom Pelissero, Dallas Cowboys quarterback Dak Prescott will "likely" need surgery, meaning the end of his season. The signal-caller plans to see "one final hamstring specialist." But it doesn't appear he'll receive a different prognosis. Fortunately, barring a setback, Prescott will be ready to go to begin the 2025-26 campaign. Without question, the Cowboys haven't met expectations this season. But without Prescott, the team's outlook is less favorable, although Cooper Rush will do his best. Of course, fantasy managers shouldn't dismiss the idea of starting Rush at some point. Still, he needs to play better than he did in the Week 9 loss to the Falcons before earning a spot in any fantasy lineup.

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Atlanta Falcons running back Tyler Allgeier found the end zone last week to the displeasure of Bijan Robinson managers, and if he hadn't it would have been a terribly quiet day, logging just six carries for 18 yards while not recording even a single target for the second consecutive week. Allgeier's involvement has been a bit unpredictable, receiving six or less carries in two of the last four weeks, while the other two weeks he saw 12 or more carries. The 24-year-old at least had a solid yards per carry (YPC) average through Week 7, but over the last two weeks his YPC is just 2.8. On the bright side, the Falcons are 3.5-point favorites this week against a reeling Saints team so there could be more opportunities if Atlanta is playing with a lead, and the BYU product rushed 8 times for 60 yards against them earlier season. Nevertheless, without a clear path to production, Allgeier is a risky RB3/Flex play this week.

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The San Francisco 49ers D/ST is coming off a bye and is in Tampa this week to take on a quality Buccaneers offense. Tampa Bay is fifth in the NFL in yards per game, mostly due to a resurgent Baker Mayfield leading the sixth-ranked passing attack in football. The Bucs are beat up at wide receiver, with Mike Evans (hamstring) ruled out and Chris Godwin (ankle) out for the season, but that didn't stop them from posting 24 points last week against a very good Kansas City Chiefs defense. They are in the middle of the pack in giveaways and times sacked. The 49ers are the fourth-ranked D/ST in fantasy by being solid but unspectacular in all relevant categories -- sacks, takeaways, touchdowns, and points against. In the secondary, they will be without CB Charvarius Ward (personal), and S Malik Mustapha (calf) is questionable. Edge Nick Bosa (hip) has been limited all week and seems to be on the wrong side of questionable. The 49ers D/ST is at No. 9 in the RotoBaller's Week 10 rankings.

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Los Angeles Rams running back Kyren Williams should be viewed as a high-end RB1 when he faces the Miami Dolphins on Monday evening. Despite coming off his worst outing of the campaign last weekend, Williams has still averaged a stellar 19.0 PPR points per game with ten total touchdowns in eight games. The Notre Dame product has averaged 20.1 attempts and 2.5 receptions per game which shows how much of an integral role he plays in the Los Angeles offense. Last weekend, the No.2 running back Blake Corum logged only one offensive snap while Williams saw all the others. This week, the 24-year-old will face a Miami defense that has allowed the sixth-most PPR points to opposing RBs which makes him a safe, high-end RB1 in all formats.

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Los Angeles Rams quarterback Matthew Stafford could have another successful fantasy outing despite the difficult matchup in Week 10. With both of his top wideouts, Cooper Kupp and Puka Nacua back in action, Stafford has averaged an impressive 26.3 PPR points over the past two weeks. In this span, Stafford has thrown at least two passing scores in each game and averaged 288.5 yards per game. On Monday, Stafford will face a tough Miami defense who has allowed the fewest points to opposing QBs this season. However, despite the unappealing matchup, his two star wideouts will provide Stafford with enough upside to consider him a low-end QB1 in all formats.

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New York Jets defensive lineman Solomon Thomas (knee) has been ruled out for Sunday's contest against the Arizona Cardinals, according to Adam Schefter of ESPN. Thomas sustained his knee injury during last Thursday's victory over the Houston Texans and was unable to participate in any team practices this week. Thomas will now set his sights on returning in Week 11 to face the Indianapolis Colts. This season, the 29-year-old has tallied 2.5 sacks and 16 tackles (eight solo) with one pass deflection. Fantasy managers should expect Will McDonald, Quinnen Williams, Javon Kinlaw, and Michael Clemons to see the majority of the snaps on the defensive line with Hasson Reddick and Leonard Taylor III rotating in.

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Houston Texans wide receiver Tank Dell (back) is listed as questionable but is expected to suit up on Sunday evening to face the Detroit Lions, according to Aaron Wilson of KPRC2. Dell popped up on the injury report on Friday and was listed as a limited participant. However, given this report, fantasy managers should not be overly concerned with his availability over the weekend. Last week, Dell operated as the top wideout with Nico Collins (hamstring) still sidelined and Stefon Diggs (knee) out with a torn ACL. In that game, Dell brought in a season-high 126 yards off six receptions. Collins is also listed as questionable, but if Dell is able to play, he should be viewed as a solid WR2 given the matchup against the Lions, who have allowed the third-most PPR points to opposing wideouts.

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Miami Dolphins wide receiver Tyreek Hill (wrist) remains in uncertain status for Monday's game against the Los Angeles Rams. According to Cameron Wolfe of the NFL Network Hill is dealing with a wrist injury that is "heating up." Head coach Mike McDaniel also noted that he will play "if his body lets him." Fantasy managers should continue to monitor his status throughout the weekend as he will likely carry an injury designation for Monday's game. After struggling through most of October without Tua Tagovailoa at quarterback, Hill has gone to eclipse double-digit PPR points in each of the past two games. If Hill is able to suit up, fantasy managers should view him as a high-end WR1. If not, Jaylen Waddle would see the majority of targets and be viewed as a high-end WR2.

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Miami Dolphins wide receiver Dee Eskridge (personal) will not travel with the team and has been ruled out for Monday's contest against the Los Angeles Rams. Eskridge did not participate in practice on Thursday due to a personal matter and will now set his sights on returning in Week 11 to face the Las Vegas Raiders. Eskridge has been operating as a depth option in the Miami wide receiver room and caught just one pass over the past two weeks. In addition, Tyreek Hill's (wrist) status is also up in the air for Monday's game. This could potentially leave Jaylen Waddle and Odell Beckham Jr. as the lone wideouts for Miami on Monday.

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San Francisco 49ers tight end George Kittle will take on the Buccaneers in Tampa for the team's Week 10 contest on Sunday. In Week 8 against Dallas, Kittle had a week-winning game, catching six of seven targets for 128 yards and a touchdown. The book on Kittle in fantasy has been boom/bust for years, but in 2024 it's been all boom. After a six-point game in Week 1, Kittle has outperformed projections in each subsequent game. He is now averaging 15.2 half-PPR points per game, while the second-ranked TE Brock Bowers sits at 11.2 PPG. It remains to be seen what the effect of an active Christian McCaffrey (Achilles) will be on Kittle's target share, but even if he takes a slight hit, he'll remain an elite option at an otherwise frustrating position. The Bucs present an excellent opportunity to keep the good times rolling, having allowed the third-most TE fantasy points this year. Unsurprisingly, Kittle is projected as the overall TE1 coming into Week 10.

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Miami Dolphins safety Jevon Holland (hand, knee) is optimistic that he will be able to play on Monday Night Football in Week 10 against the Los Angeles Rams, according to head coach Mike McDaniel. While Holland is hoping to be able to play, he said on Friday that he'll be a game-time decision on Monday. The 24-year-old defensive back injured his knee in the Week 8 loss to the Arizona Cardinals and was not active for last week's loss to the division-rival Buffalo Bills. After missing practice on Thursday this week, Holland put in a limited session on Friday, giving him a chance to return on Monday. The Dolphins defense could surely use Holland back on the field against a high-octane Rams passing attack that has both receivers Cooper Kupp and Puka Nacua back. In six games this year, Holland has 26 tackles (18 solo), two pass breakups and a forced fumble.

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The Indianapolis Colts elevated wide receiver Laquon Treadwell from the practice squad to the active roster for Sunday's game against the Buffalo Bills after the team ruled out Michael Pittman Jr. (back) for Week 10. It will be the first week that Treadwell has been active for the Colts in 2024, and he'll be unlikely to make any noise in fantasy as receiver depth for Indy. With Pittman inactive, Josh Downs should serve as quarterback Joe Flacco's favorite target, with Alec Pierce and rookie Adonai Mitchell also seeing more opportunities. Treadwell, 29, only played in five games last year with the Baltimore Ravens and caught just one of three targets for a 16-yard gain. The previous year he caught six of 10 targets for 42 scoreless yards in six contests with the Seattle Seahawks.

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Miami Dolphins right tackle Austin Jackson (knee) will not play in the Monday night game against the Los Angeles Rams in Week 10. Head coach Mike McDaniel said Jackson popped up with a knee injury after the Week 9 loss to the division-rival Buffalo Bills. It's unknown if Jackson will need surgery, but thankfully his injury doesn't appear to be season-ending. With Jackson sidelined on Monday, veteran Kendall Lamm and rookie Patrick Paul are both options to replace him on the right side of the offensive line against the Rams. Miami comes into Week 10 action riding a three-game losing streak despite quarterback Tua Tagovailoa back in the starting role under center the last two weeks. The Dolphins currently sit at 2-6 and are 2.5 games behind the Denver Broncos for the seventh seed in the AFC.

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San Francisco 49ers running back Christian McCaffrey (Achilles), who is listed as questionable to play in Week 10 against the Tampa Bay Buccaneers, said he feels great and is ready to make his 2024 debut on Sunday. McCaffrey missed the first eight games with bilateral Achilles tendonitis but completed his first full week of practice and will be activated from Injured Reserve on Saturday. CMC also dealt with a calf strain in early August and missed most of training camp in the summer. Now that the reigning Offensive Player of the Year is back, fantasy managers want to know how effective he'll be against Tampa and how much work he'll get. While McCaffrey should operate as San Fran's lead back on Sunday, he'll more than likely have his workload monitored, which will make him a more risky RB1. Jordan Mason will now lose most of his fantasy value as he reverts to a backup role.

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Although the move isn't yet official, the Dallas Cowboys will put quarterback Dak Prescott (hamstring) on Injured Reserve, which means he'll be required to miss at least the next four games, according to executive vice president Stephen Jones. Multiple sources said Prescott is expected to need six to eight weeks of recovery for the partial avulsion of his hamstring that he suffered in the Week 9 loss to the Falcons. If he need surgery, Prescott would miss the rest of the regular season. If he doesn't have surgery and recovers quickly, Prescott would be eligible to return on Dec. 9 against the Bengals in Week 14. However, the prevailing sentiment is that Prescott will likely need more time than that to recover. It's a huge blow to the already disappointing 3-5 Cowboys. Their offense will now be led by backup QB Cooper Rush, who will be no better than a low-end QB2 in superflex fantasy leagues moving forward.

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Miami Dolphins wide receiver Tyreek Hill (wrist) is "doing everything possible" in order to play on Monday night against the Los Angeles Rams after he was added to the Week 10 injury report after missing practice on Friday, according to head coach Mike McDaniel. The head coach said Hill's wrist injury has been "heating up," and the team wants to give it a chance to "cool down." Miami is taking things day-to-day with Hill, who sounds likely to get a questionable tag on Saturday's final injury report. For what it's worth, McDaniel is optimistic Hill will be able to play. The Cheetah leads all Dolphins players with 446 receiving yards in 2024, but he has just one TD and it's his worst statistical start since coming to Miami in 2022. The good news is he has averaged 76 yards in the last two games with quarterback Tua Tagovailoa back. If Hill can't play, it will put Jaylen Waddle in the No. 1 role against LA.

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The Denver Broncos defense/special teams unit is tied for third in the league with the Chicago Bears in overall fantasy points, but they represent a shaky fantasy option as they head into a tough Week 10 matchup against the undefeated Kansas City Chiefs and Patrick Mahomes. While KC's offense hasn't been as explosive as in years past, they are definitely more dangerous now after trading for receiver DeAndre Hopkins. And while Denver's D has been one of the stingier units in 2024 -- they're allowing the third-fewest points per game (17.9) -- the Ravens proved last week that they can still be dominated. The Chiefs offense hasn't been perfect with 12 giveaways on the season, but they also haven't been an ideal matchup for opposing defenses, allowing only 5.0 fantasy points per game. There just isn't a ton of upside for Denver's D/ST on the road against the defending Super Bowl champs.

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Denver Broncos rookie wide receiver Devaughn Vele probably isn't going to break out in the team's Week 10 matchup on the road against the division-rival Kansas City Chiefs, a defense that has allowed the eighth-fewest half-PPR fantasy points to opposing receivers this year. The seventh-round pick out of Utah has some intriguing long-term upside working with quarterback Bo Nix in Denver, but he's just not anywhere near the fantasy radar in single-year leagues. In just five games played in his first year in the NFL, Vele has 18 catches on 23 targets for 176 yards and no touchdowns. Courtland Sutton, the clear WR1 in Denver, is really the only fantasy relevant receiver that the Broncos have to offer in 2024. Even with Josh Reynolds (finger) on Injured Reserve, Vele just hasn't managed to stand out while competing for targets with Lil'Jordan Humphrey and fellow rookie Troy Franklin.

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Fantasy managers should be able to find more reliable kicking options in Week 10 than Denver Broncos kicker Wil Lutz, who has been disappointing each of the last two weeks. Lutz checks in as the No. 7 kicker in overall fantasy points entering a Week 10 showdown against the undefeated Kansas City Chiefs, but he's managed just one field goal and five extra points in Weeks 8 and 9 against the Carolina Panthers and Baltimore Ravens, respectively. The 30-year-old has been one of the most accurate in the league, missing just one of his 19 field-goal attempts on the year while making all 17 of his extra points, but volume may be hard to come by on Sunday in a hostile environment against a KC defense that has allowed just 18.4 points per game, fourth-fewest in the NFL. Lutz has been money when given opportunities in 2024, but there's minimal fantasy upside for him this weekend.

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