Los Angeles Chargers rookie wide receiver Tre' Harris (undisclosed) did not participate in team drills during practice on Thursday, according to Daniel Popper of The Athletic. Harris left early from the team's practice on Wednesday with members of the training staff, but his exact ailment is unclear. A second-round pick out of Ole Miss, Harris has had a solid preseason and could be in line to open the season as the WR3 in Los Angeles. With Quentin Johnson (concussion) also sidelined, the Chargers could be forced to turn to veteran Jalen Reagor or rookie Keandre Lambert-Smith. If Harris' injury does not prove to be serious, he has some appeal as a high-upside late-round target in fantasy.

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Indianapolis Colts running back Tyler Goodson (elbow) did not practice on Thursday, according to James Boyd of The Athletic. Goodson injured his elbow in preseason action on Saturday against the Green Bay Packers and has not practiced since. He's unlikely to play in the preseason finale against the Cincinnati Bengals, but Goodson reportedly has a chance to be ready for Week 1. The 24-year-old has logged 45 career rush attempts for 240 yards and one touchdown across his first two NFL seasons. Colts rookie running back DJ Giddens appeared to have jumped Goodson as the primary backup to Jonathan Taylor even before Goodson's injury. As a result, Goodson has minimal fantasy appeal even as a handcuff option.

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Seattle Seahawks rookie quarterback Jalen Milroe will start and play the entirety of the team's final preseason game against the Green Bay Packers, according to Seahawks head coach Mike Macdonald. A third-round pick out of Alabama, Milroe is a developmental prospect who is expected to open the season behind both Sam Darnold and Drew Lock on the Seahawks QB depth chart. In two preseason games so far, Milroe has thrown for 107 yards on 15 pass attempts and rushed for 56 yards on eight rush attempts. His dual-threat ability makes him an intriguing dynasty prospect, but he's unlikely to be fantasy-relevant in 2025.

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Indianapolis Colts wide receiver Josh Downs (hamstring) was held out of practice again on Thursday, per James Boyd of The Athletic. Downs exited the team's joint practice with the Green Bay Packers last Thursday with a left hamstring injury and has not practiced since. The 24-year-old is one of the better slot and short-area receivers in the NFL, so his presence on the field is crucial for Colts quarterback Daniel Jones. If Downs were to miss time, it would likely benefit the target volume for wide receiver Michael Pittman Jr. and rookie tight end Tyler Warren. Assuming Downs' availability for the start of the regular season is not under threat, he profiles as a WR4 with a fairly safe floor, particularly in PPR-scoring formats.

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Dynasty | Saints quarterback Spencer Rattler will start the final preseason game for New Orleans. Dynasty Analysis: Rattler seemingly has the lead in the competition against rookie Tyler Shough but neither has done enough to exactly close the deal. Rattler will have to impress the Saints coaching staff to hold off Shough as New Orleans likely would benefit from handing the reigns to the rookie. Still, Shough just hasn't looked the part as of yet. Regardless, this looks like one of the NFL's worst rosters and neither quarterback is much of an option in dynasty leagues. Shough should certainly be on rosters and Rattler would likely merit the same should he win the job.

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Dynasty | Eagles wide receiver Johnny Wilson will miss the season with a knee injury. Dynasty Analysis: Wilson was making a case for playing time behind AJ Brown and DeVonta Smith but this obviously throws cold water on that idea. This could also help explain why the Eagles recently traded for John Metchie. Regardless, any sleeper value Wilson may have had in dynasty leagues has evaporated, at least for this season.

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Los Angeles Chargers head coach Jim Harbaugh said that quarterback Justin Herbert and the rest of the starters will not play in the preseason finale on Saturday against the San Francisco 49ers. Backup QB Trey Lance will get the start under center and will play one to two series. Taylor Heinicke will come in after Lance, followed by DJ Uiagalelei, who will play the rest of the game. Lance and Heinicke are competing for the No. 2 job this summer, although it's unclear if Lance has the leg up based on the fact that he's making the start in the preseason finale. Neither Lance nor Heinicke figure to be on the field much behind Herbert, who has been one of the toughest QBs in the league since entering the NFL in 2020. Herbert missed four games due to injury in 2023 but has started all 79 of the games he's appeared in over the last five seasons.

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Los Angeles Chargers wide receiver Quentin Johnston (concussion), who suffered a scary-looking concussion in the team's second preseason game last Saturday against the Los Angeles Rams, was back at practice on Thursday, according to Kris Rhim of ESPN.com. While the 23-year-old might not be completely cleared from the league's concussion protocol, the fact that he's back on the field is a good sign that he should gain full clearance to be active for the Week 1 regular-season opener on Friday, Sept. 5, against the division-rival Kansas City Chiefs in Brazil. Johnston should go undrafted in standard 12-team fantasy leagues this fall. The former 21st overall pick in 2023 out of TCU did improve with a 55-711-8 line in 15 regular-season games (11 starts) in 2024, but he continues to struggle with drops and is fighting for the WR3 role with rookie Tre' Harris behind Ladd McConkey and Keenan Allen.

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Los Angeles Chargers head coach Jim Harbaugh was non-committall on running back Najee Harris (eye) when asked if he'll be ready for the Week 1 regular-season opener on Friday, Sept. 5, against the division-rival Kansas City Chiefs in Brazil. "When Najee is ready to play, Najee will be ready to play. Right now, to take it past today would be going over the legal limit. That would take your over the legal limit of what-ifs," Harbaugh said. Harris remains on the Non-Football Injury list after a fireworks accident on the Fourth of July injured his eye, and he was seen working out on a side field again on Wednesday. The 27-year-old's representation is saying that he'll be ready for the regular-season opener, but given the fact he's missed all of training camp and the preseason to this point, it seems likely that rookie first-rounder Omarion Hampton will be more involved than Harris in L.A.'s backfield.

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Cleveland Browns head coach Kevin Stefanski said that quarterback Joe Flacco will make the start in the preseason finale on Saturday against the Los Angeles Rams, with the starters expected to go around 25 to 30 plays. Rookie Dillon Gabriel will enter the game after Flacco, followed by rookie fifth-rounder Shedeur Sanders third. Kenny Pickett (hamstring) continues to deal with a hamstring injury that he suffered in late July, but he did return to some practice drills this week. The order for this weekend's game suggests that Gabriel remains ahead of Sanders on the team's QB depth chart, but the Browns could keep all four signal-callers on the active 53-man roster heading into Week 1 against the division-rival Cincinnati Bengals. If Pickett is healthy for the start of the regular season, he's expected to be the backup to Flacco.

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Dynasty | Patriots wide receiver Ja'Lynn Polk will go on injured reserve and will miss the season. Dynasty Analysis: After a 12/87/2 rookie season disaster, Polk will now miss his entire Sophomore season. It's a massive blow to Polk's dynasty value after there was speculation he was already on the roster bubble. The former second round pick is seeing his dynasty value plummet and this news will honestly see him be placed on a lot of waiver wires in dynasty leagues as he unfortunately looks like a bust at the moment.

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Carolina Panthers backup quarterback Andy Dalton (elbow) is being held out of the team's preseason finale on Thursday night against the Pittsburgh Steelers, according to Panthers beat writer Darin Gantt. Starter Bryce Young will also be held out, leaving QB duties on Thursday to Jack Plummer and Bryce Perkins, who was just signed on Monday. The 37-year-old Dalton suffered a muscle strain in his right elbow in the team's second preseason tilt last Saturday against the Houston Texans. While the injury isn't considered overly serious, Dalton is strictly focused on being available for the club's Week 1 regular-season opener on Sunday, Sept. 7, against the Jacksonville Jaguars. The Red Rifle is purely a backup at this point in his career. In six games (five starts) played last year in Carolina when Young was benched, he threw for 989 yards, seven touchdowns and six interceptions.

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Miami Dolphins running back Jaylen Wright (undisclosed) walked off the practice field on Thursday slowly with an apparent injury and was flanked by a trainer before heading into the team's facilities for further evaluation, according to Cameron Wolfe of NFL Network. With De'Von Achane (calf) not practicing at all this week with a calf injury, Wright's injury status becomes even more important heading into Week 1 of the regular season in early September. Rookie Ollie Gordon II took most of the team's RB reps in practice on Thursday. We'll bring you more information on Wright's status when we have it. Assuming Miami's backfield options are all fully healthy, the 22-year-old Wright figures to be the RB2 behind Achane. The former fourth-rounder has plenty of home run ability himself and had 249 rushing yards on 68 attempts in Year 1 in 2024.

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Jacksonville Jaguars head coach Liam Coen said on Thursday that quarterback Trevor Lawrence and the rest of the starters will not play in the preseason finale on Saturday against the Miami Dolphins. Lawrence and the rest of the starting offense will not be seen again until the regular-season opener on Sunday, Sept. 7, against the Carolina Panthers. The 25-year-old signal-caller from Clemson has not lived up to the hype of being the No. 1 overall pick back in 2021, and on top of it, he played a career-low 10 games in 2024 due to injury. Lawrence should bounce back this year as long as he stays healthy, though, especially in Coen's offensive scheme with an added weapon in two-way star Travis Hunter. Fantasy managers aren't going to be drafting Lawrence as anything more than a low-end QB2 with upside in upcoming drafts.

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Los Angeles Rams head coach Sean McVay said that quarterback Matthew Stafford (back) has been a full participant at practice all week. When asked how Stafford has looked the last few days, McVay said, "He's looked like the stud we know." However, Stafford will not travel with the team to Cleveland for their preseason finale against the Browns on Saturday. The 37-year-old veteran has now practiced four straight days without restrictions and appears to be on track to be ready for the Week 1 regular-season opener on Sunday, Sept. 7, against the Houston Texans. He may not be 100% to begin the season, but it's good news for receivers Puka Nacua and Davonte Adams that Stafford should be on the field in Week 1. Expect Stafford to be limited early in the practice week next week. For fantasy purposes, he has become a low-end QB2 with injury risk.

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Denver Broncos head coach Sean Payton confirmed that quarterback Bo Nix and the rest of the team's starters will play eight to 10 offensive snaps in the preseason finale on Saturday against the New Orleans Saints. Nix played briefly in the preseason opener against the San Francisco 49ers and looked rusty before not suiting up for the second preseason game last weekend versus the Arizona Cardinals. The 25-year-old will get one final brief tune-up against another squad this weekend before a Week 1 season-opening matchup against the Tennessee Titans on Sunday, Sept. 7. The former Oregon Duck started off slow in Payton's offense in his rookie campaign before hitting his stride and taking off, throwing for 3,775 yards, 29 touchdowns and 12 interceptions. If Nix continue to grow in Payton's offense in Year 2, he should be in play as at least a low-end QB1 in fantasy.

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Green Bay Packers head coach Matt LaFleur shut down any rumors of wide receiver Romeo Doubs (back) being cut following training camp. When asked about the potential for Doubs to be cut on the Up & Adams show, the head coach said, "That will not happen." The Packers can't really even afford to cut Doubs if they wanted to heading into the start of the 2025 regular season with how banged up their receivers room is. Christian Watson (knee) is going to begin the year on the Physically Unable to Perform list and Doubs, Jayden Reed (foot) and Dontayvion Wicks (calf) have also been banged up. Doubs missed some practice time with a back injury but should be good for the Week 1 regular-season opener on Sunday, Sept. 7, against the division-rival Detroit Lions. The 25-year-old Doubs should be on the roster, but he's probably going to need Reed to miss time to be a realistic flex option in 12-team fantasy leagues.

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New Orleans Saints second-year quarterback Spencer Rattler will make the start for Saturday's preseason finale against the Denver Broncos, head coach Kellen Moore announced after practice on Thursday. The competition for the starting QB job remains neck and neck between Rattler and rookie second-rounder Tyler Shough, and Rattler making the "start" doesn't really mean he's the favorite to be named the Week 1 starter after Saturday's contest. The 24-year-old looked better than Shough did in the second preseason contest against the Jacksonville Jaguars, though, so if he can do that for a second straight week, Moore will likely name Rattler as the starter under center to begin the season. Rattler, a fifth-rounder last year, looked like a rookie in his seven games (six starts), throwing for 1,317 yards, four touchdowns and five picks. Fantasy managers will want to avoid the Saints' QB situation.

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New England Patriots wide receiver Ja'Lynn Polk (shoulder) will miss the entire 2025 season due to a shoulder injury that needs surgery, sources told FOX Sports' Jordan Schultz on Thursday. Polk visited with multiple specialists before opting for season-ending surgery, but going under the knife was determined to be the best course of action. The former second-round pick last year will be hoping to be fully healthy for the start of the 2026 season. Polk disappointed in his first year in New England last year, catching just 12 of his 33 targets for 87 yards and two touchdowns in 15 games (seven starts), but to be fair, he didn't have much of a chance in the Patriots' low-scoring offense. He will now miss his entire sophomore season, which gives rookies Kyle Williams and Efton Chism III greater chances of making the 53-man roster as depth behind Stefon Diggs, Mack Hollins and DeMario Douglas.

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Jacksonville Jaguars rookie two-way star Travis Hunter (upper body) was held out of Thursday's joint practice with the Miami Dolphins due to an upper-body injury, and he will not play in the team's preseason finale on Saturday night against Miami, according to Michael DiRocco of ESPN. The Jaguars considered having Hunter practice, but they took the precautionary route since they don't want him to aggravate the injury that has kept the Heisman Trophy winner out of the team's three previous practices and the second preseason game. The 22-year-old second overall pick out of Colorado suffered the injury in the team's scrimmage on Aug. 14. Although he hasn't been practicing with the rest of the team, he took part in individual drills on Tuesday and Wednesday, suggesting he should be just fine for the Week 1 regular-season opener on Sunday, Sept. 7, versus the Carolina Panthers.

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