Washington Commanders quarterback Marcus Mariota (Achilles) is currently battling Achilles tendinitis, but the veteran expects to be ready to go for Week 1. Mariota is entering his second season as the backup to Jayden Daniels in Washington. The 31-year-old is one of the most experienced backup quarterbacks in the NFL with 74 career starts under his belt, although just 13 of those have come in the past five seasons. If Daniels were to get injured, Mariota's rushing ability (2,156 career rushing yards) would give him some fantasy appeal.

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Los Angeles Chargers wide receiver Jalen Reagor (lower body) returned to team drills in practice on Wednesday, according to Daniel Popper of The Athletic. Reagor has been battling through a lower-body injury since late July. The 26-year-old played in eight games for the Chargers in 2024, recording seven catches for 100 yards. With wide receivers Quentin Johnston (concussion) and Tre' Harris (undisclosed) both dealing with ailments, Reagor has a chance to make the Chargers' 53-man roster and earn playing time early in the season. He's recorded just 22 catches in his last 36 games played, so Reagor should not be on the radar of fantasy managers.

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Dynasty | Eagles wide receiver Johnny Wilson will miss the season with a knee injury. Dynasty Analysis: Wilson was making a case for playing time behind AJ Brown and DeVonta Smith but this obviously throws cold water on that idea. This could also help explain why the Eagles recently traded for John Metchie. Regardless, any sleeper value Wilson may have had in dynasty leagues has evaporated, at least for this season.

Carolina Panthers tight end Tommy Tremble (back) was activated from the physically unable to perform list on Thursday, according to Darin Gantt of Panthers.com. Gantt writes that the team is hopeful that Tremble will be able to play in Week 1 after undergoing back surgery in May. The 25-year-old is entering his fifth season with the Panthers and has recorded exactly 32 targets and 23 receptions in each of the past two years. Tremble is not a fantasy-relevant tight end, but he's a valuable player to Carolina because of his run-blocking ability. He threatens to vulture snaps and targets away from Panthers tight end Ja'Tavion Sanders, who offers far more upside as a receiver.

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Los Angeles Rams rookie tight end Terrance Ferguson (groin) will play in the team's final preseason game against the Cleveland Browns on Saturday, according to ESPN's Sarah Bishop. Ferguson missed more than two weeks with a groin injury, but returned to practice on Monday. The second-round pick out of Oregon has yet to play in the preseason, so Saturday will be his first taste of NFL game action. The Rams have a very deep tight end room, so Ferguson could easily start the season behind veterans Tyler Higbee and Colby Parkinson on the depth chart. The 22-year-old Ferguson is a name to keep an eye on in dynasty leagues, but he's unlikely to factor in fantasy during the 2025 season.

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Los Angeles Chargers rookie wide receiver Tre' Harris (undisclosed) did not participate in team drills during practice on Thursday, according to Daniel Popper of The Athletic. Harris left early from the team's practice on Wednesday with members of the training staff, but his exact ailment is unclear. A second-round pick out of Ole Miss, Harris has had a solid preseason and could be in line to open the season as the WR3 in Los Angeles. With Quentin Johnson (concussion) also sidelined, the Chargers could be forced to turn to veteran Jalen Reagor or rookie Keandre Lambert-Smith. If Harris' injury does not prove to be serious, he has some appeal as a high-upside late-round target in fantasy.

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Indianapolis Colts running back Tyler Goodson (elbow) did not practice on Thursday, according to James Boyd of The Athletic. Goodson injured his elbow in preseason action on Saturday against the Green Bay Packers and has not practiced since. He's unlikely to play in the preseason finale against the Cincinnati Bengals, but Goodson reportedly has a chance to be ready for Week 1. The 24-year-old has logged 45 career rush attempts for 240 yards and one touchdown across his first two NFL seasons. Colts rookie running back DJ Giddens appeared to have jumped Goodson as the primary backup to Jonathan Taylor even before Goodson's injury. As a result, Goodson has minimal fantasy appeal even as a handcuff option.

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Seattle Seahawks rookie quarterback Jalen Milroe will start and play the entirety of the team's final preseason game against the Green Bay Packers, according to Seahawks head coach Mike Macdonald. A third-round pick out of Alabama, Milroe is a developmental prospect who is expected to open the season behind both Sam Darnold and Drew Lock on the Seahawks QB depth chart. In two preseason games so far, Milroe has thrown for 107 yards on 15 pass attempts and rushed for 56 yards on eight rush attempts. His dual-threat ability makes him an intriguing dynasty prospect, but he's unlikely to be fantasy-relevant in 2025.

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Indianapolis Colts wide receiver Josh Downs (hamstring) was held out of practice again on Thursday, per James Boyd of The Athletic. Downs exited the team's joint practice with the Green Bay Packers last Thursday with a left hamstring injury and has not practiced since. The 24-year-old is one of the better slot and short-area receivers in the NFL, so his presence on the field is crucial for Colts quarterback Daniel Jones. If Downs were to miss time, it would likely benefit the target volume for wide receiver Michael Pittman Jr. and rookie tight end Tyler Warren. Assuming Downs' availability for the start of the regular season is not under threat, he profiles as a WR4 with a fairly safe floor, particularly in PPR-scoring formats.

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Dynasty | Saints quarterback Spencer Rattler will start the final preseason game for New Orleans. Dynasty Analysis: Rattler seemingly has the lead in the competition against rookie Tyler Shough but neither has done enough to exactly close the deal. Rattler will have to impress the Saints coaching staff to hold off Shough as New Orleans likely would benefit from handing the reigns to the rookie. Still, Shough just hasn't looked the part as of yet. Regardless, this looks like one of the NFL's worst rosters and neither quarterback is much of an option in dynasty leagues. Shough should certainly be on rosters and Rattler would likely merit the same should he win the job.

From Dynasty League Fantasy

Los Angeles Chargers head coach Jim Harbaugh said that quarterback Justin Herbert and the rest of the starters will not play in the preseason finale on Saturday against the San Francisco 49ers. Backup QB Trey Lance will get the start under center and will play one to two series. Taylor Heinicke will come in after Lance, followed by DJ Uiagalelei, who will play the rest of the game. Lance and Heinicke are competing for the No. 2 job this summer, although it's unclear if Lance has the leg up based on the fact that he's making the start in the preseason finale. Neither Lance nor Heinicke figure to be on the field much behind Herbert, who has been one of the toughest QBs in the league since entering the NFL in 2020. Herbert missed four games due to injury in 2023 but has started all 79 of the games he's appeared in over the last five seasons.

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Los Angeles Chargers wide receiver Quentin Johnston (concussion), who suffered a scary-looking concussion in the team's second preseason game last Saturday against the Los Angeles Rams, was back at practice on Thursday, according to Kris Rhim of ESPN.com. While the 23-year-old might not be completely cleared from the league's concussion protocol, the fact that he's back on the field is a good sign that he should gain full clearance to be active for the Week 1 regular-season opener on Friday, Sept. 5, against the division-rival Kansas City Chiefs in Brazil. Johnston should go undrafted in standard 12-team fantasy leagues this fall. The former 21st overall pick in 2023 out of TCU did improve with a 55-711-8 line in 15 regular-season games (11 starts) in 2024, but he continues to struggle with drops and is fighting for the WR3 role with rookie Tre' Harris behind Ladd McConkey and Keenan Allen.

From RotoBaller

Los Angeles Chargers head coach Jim Harbaugh was non-committall on running back Najee Harris (eye) when asked if he'll be ready for the Week 1 regular-season opener on Friday, Sept. 5, against the division-rival Kansas City Chiefs in Brazil. "When Najee is ready to play, Najee will be ready to play. Right now, to take it past today would be going over the legal limit. That would take your over the legal limit of what-ifs," Harbaugh said. Harris remains on the Non-Football Injury list after a fireworks accident on the Fourth of July injured his eye, and he was seen working out on a side field again on Wednesday. The 27-year-old's representation is saying that he'll be ready for the regular-season opener, but given the fact he's missed all of training camp and the preseason to this point, it seems likely that rookie first-rounder Omarion Hampton will be more involved than Harris in L.A.'s backfield.

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Cleveland Browns head coach Kevin Stefanski said that quarterback Joe Flacco will make the start in the preseason finale on Saturday against the Los Angeles Rams, with the starters expected to go around 25 to 30 plays. Rookie Dillon Gabriel will enter the game after Flacco, followed by rookie fifth-rounder Shedeur Sanders third. Kenny Pickett (hamstring) continues to deal with a hamstring injury that he suffered in late July, but he did return to some practice drills this week. The order for this weekend's game suggests that Gabriel remains ahead of Sanders on the team's QB depth chart, but the Browns could keep all four signal-callers on the active 53-man roster heading into Week 1 against the division-rival Cincinnati Bengals. If Pickett is healthy for the start of the regular season, he's expected to be the backup to Flacco.

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Dynasty | Patriots wide receiver Ja'Lynn Polk will go on injured reserve and will miss the season. Dynasty Analysis: After a 12/87/2 rookie season disaster, Polk will now miss his entire Sophomore season. It's a massive blow to Polk's dynasty value after there was speculation he was already on the roster bubble. The former second round pick is seeing his dynasty value plummet and this news will honestly see him be placed on a lot of waiver wires in dynasty leagues as he unfortunately looks like a bust at the moment.

From Dynasty League Fantasy

Carolina Panthers backup quarterback Andy Dalton (elbow) is being held out of the team's preseason finale on Thursday night against the Pittsburgh Steelers, according to Panthers beat writer Darin Gantt. Starter Bryce Young will also be held out, leaving QB duties on Thursday to Jack Plummer and Bryce Perkins, who was just signed on Monday. The 37-year-old Dalton suffered a muscle strain in his right elbow in the team's second preseason tilt last Saturday against the Houston Texans. While the injury isn't considered overly serious, Dalton is strictly focused on being available for the club's Week 1 regular-season opener on Sunday, Sept. 7, against the Jacksonville Jaguars. The Red Rifle is purely a backup at this point in his career. In six games (five starts) played last year in Carolina when Young was benched, he threw for 989 yards, seven touchdowns and six interceptions.

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Miami Dolphins running back Jaylen Wright (undisclosed) walked off the practice field on Thursday slowly with an apparent injury and was flanked by a trainer before heading into the team's facilities for further evaluation, according to Cameron Wolfe of NFL Network. With De'Von Achane (calf) not practicing at all this week with a calf injury, Wright's injury status becomes even more important heading into Week 1 of the regular season in early September. Rookie Ollie Gordon II took most of the team's RB reps in practice on Thursday. We'll bring you more information on Wright's status when we have it. Assuming Miami's backfield options are all fully healthy, the 22-year-old Wright figures to be the RB2 behind Achane. The former fourth-rounder has plenty of home run ability himself and had 249 rushing yards on 68 attempts in Year 1 in 2024.

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Jacksonville Jaguars head coach Liam Coen said on Thursday that quarterback Trevor Lawrence and the rest of the starters will not play in the preseason finale on Saturday against the Miami Dolphins. Lawrence and the rest of the starting offense will not be seen again until the regular-season opener on Sunday, Sept. 7, against the Carolina Panthers. The 25-year-old signal-caller from Clemson has not lived up to the hype of being the No. 1 overall pick back in 2021, and on top of it, he played a career-low 10 games in 2024 due to injury. Lawrence should bounce back this year as long as he stays healthy, though, especially in Coen's offensive scheme with an added weapon in two-way star Travis Hunter. Fantasy managers aren't going to be drafting Lawrence as anything more than a low-end QB2 with upside in upcoming drafts.

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Free-agent QB Tanner Mordecai (49ers) signed with the San Francisco 49ers Thursday, Aug. 21. Terms of the contract were not disclosed. The team also released QB Nate Sudfeld.

From TheHuddle

Los Angeles Rams head coach Sean McVay said that quarterback Matthew Stafford (back) has been a full participant at practice all week. When asked how Stafford has looked the last few days, McVay said, "He's looked like the stud we know." However, Stafford will not travel with the team to Cleveland for their preseason finale against the Browns on Saturday. The 37-year-old veteran has now practiced four straight days without restrictions and appears to be on track to be ready for the Week 1 regular-season opener on Sunday, Sept. 7, against the Houston Texans. He may not be 100% to begin the season, but it's good news for receivers Puka Nacua and Davonte Adams that Stafford should be on the field in Week 1. Expect Stafford to be limited early in the practice week next week. For fantasy purposes, he has become a low-end QB2 with injury risk.

From RotoBaller