San Francisco 49ers running back Christian McCaffrey (Achilles) was rested on Wednesday in the first practice of the week before being limited in Thursday's session. McCaffrey isn't in any real danger of not playing in Week 12 against the Green Bay Packers on Sunday, but the 49ers will continue to take it easy on him during the practice week after he missed the first nine weeks of the season due to bilateral Achilles tendonitis. The 28-year-old hasn't scored for his fantasy managers in his first two games of the season, but he has gone over 100 scrimmage yards in both contests, which counts for something. In addition, backup Jordan Mason has been a distant No. 2 in terms of usage. The Packers defense has been middle of the pack this year in terms of fantasy points allowed per game to RBs, but they've given up the fourth-most fantasy points to the position in the last three weeks. CMC is a must-start RB1.

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San Francisco 49ers defensive end Nick Bosa (hip) and left tackle Trent Williams (ankle) were both absent from practice on Thursday for the second straight day this week. It's bad news for the team's defensive and offensive-line standouts in terms of their availability for the upcoming game on Sunday versus the Green Bay Packers. The 27-year-old Bosa is pretty banged up right now and will need to return to practice on Friday to have a shot at playing in Week 12. The same can be said for Williams, who came out of the Week 11 loss to the division-rival Seattle Seahawks with soreness related to a nagging ankle injury. Both Bosa and Williams were questionable to play last week, but this week they could be held out entirely. Fantasy managers in IDP leagues should have a backup D-lineman in place in case Bosa is ruled out on Friday.

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San Francisco 49ers quarterback Brock Purdy (shoulder) was listed as a limited practice participant for the second straight day this week on Thursday. Purdy also didn't speak to the media after practice on Thursday, instead opting to get extra treatment for his sore right shoulder. The 24-year-old's status is a bit up in the air for Sunday's game at Lambeau Field against the hosting Green Bay Packers, but the good news is he did more throwing in warmups than he did on Wednesday. In a worst-case scenario for the Niners, Purdy would be held out this weekend in favor of Brandon Allen under center. We'll have a better idea of Purdy's status after Friday's practice. If Purdy gets more done in Friday's practice and is cleared to play by Sunday, he should be considered a low-end QB1 option in fantasy against a Packers defense that has been more stingy against the position in recent weeks.

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San Francisco 49ers tight end George Kittle (hamstring) was limited in practice for the second straight day this week on Thursday. Kittle has been dealing with some hamstring irritation of late and was held out of the Week 11 loss to the division-rival Seattle Seahawks. The 31-year-old intends to return this Sunday to face the Green Bay Packers at Lambeau Field, though, and fantasy managers need to move him back into all starting lineups. He could be a little more risky as a TE1 in his first game back after missing last week, but Kittle has been the most productive TE for fantasy managers this year when active, so he's a no-brainer must-start if he's playing. Despite missing two games this season, Kittle is the TE2 in overall fantasy points, behind only rookie Brock Bowers. Kittle's seven touchdowns lead all tight ends.

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Los Angeles Chargers outside linebacker Khalil Mack (groin) was listed as a limited participant for the team's first practice of the week on Thursday. Outside linebackers Joey Bosa (hip) and Bud Dupree (foot) and safety Derwin James Jr. (groin) were also limited. Meanwhile, linebacker Denzel Perryman (groin) was a DNP. Mack aggravated a groin injury in the Week 10 win over the Tennessee Titans and sat out of the Week 11 victory over the Cincinnati Bengals. The fact that the 33-year-old pass-rusher is practicing in the first practice of the week could be a good sign that he will return to face the Baltimore Ravens on Monday night. Even with Mack back, the Bolts' defense will have a big challenge on their hands against the reigning MVP in Lamar Jackson and a potent Ravens offense. The three-time All-Pro hasn't been quite as good in 2024 as when he registered a career-high 17 sacks last year, as he has 4.5 sacks in nine games.

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The New England Patriots removed tight end Austin Hooper (neck) from the Week 12 injury report on Thursday, which means he was a full practice participant. Hooper was limited in Wednesday's session but is now ready to roll for a divisional clash this Sunday at Hard Rock Stadium against the Miami Dolphins. The 30-year-old veteran has become more intriguing as a TE2 sleeper play in deeper leagues and DFS contests now that rookie quarterback Drake Maye is leading the offense. However, the fantasy ceiling and floor remain pretty low as he works behind Hunter Henry. Most of Hooper's production has come in the last two games, as he's caught seven of his eight targets for 99 yards and no touchdowns. Hooper's lone score of the season came back in the loss to the San Francisco 49ers back on Sept. 29. He should be on the waiver wire in most fantasy leagues.

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Green Bay Packers cornerback Jaire Alexander (knee) said on Thursday that he's dealing with a torn PCL that he suffered in the win over the Jacksonville Jaguars in Week 8. Alexander missed the Week 9 game against the Detroit Lions. The Packers had their bye in Week 10, and Alexander played just 10 defensive snaps in last week's win over the Chicago Bears before leaving the game and not returning. He's hoping to return to the All-Pro form he had in 2020 and 2022 but doesn't know exactly when he might be back with the team. Alexander did say, though, that "I just need more than 21 days of non-contact." The veteran defensive back has missed 27 of a potential 61 regular-season games since the start of 2021, with 26 of them coming due to injury. Alexander can still be an elite corner when healthy, but Green Bay's secondary will be more vulnerable in Week 12 against the San Francisco 49ers.

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Baltimore Ravens wide receiver Nelson Agholor (illness) was listed as a non-participant for the team's first practice of the week on Thursday. It's worth watching, but with the Ravens playing on Monday night in Week 12 against the Los Angeles Chargers, Agholor should be feeling better by then. We'll have a better idea of the 31-year-old's status by the time the Ravens release their final injury report for the week on Saturday. Even if Agholor is active, though, fantasy managers should have plenty of better options to throw into a flex spot in Week 12. Agholor didn't come down with his only target in the Week 11 loss to the division-rival Pittsburgh Steelers and has only 13 receptions on 26 targets for 205 yards and two touchdowns in 11 games in his second year in Baltimore.

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Baltimore Ravens running back Justice Hill (concussion) is in the league's concussion protocol but was able to put in a limited practice on Thursday. Hill apparently came out of the Week 11 loss to the Pittsburgh Steelers with a concussion and is now questionable to suit up for the Monday night showdown against the Los Angeles Chargers in Week 12. The good news is the 27-year-old has an extra day to try and clear the concussion protocol this week, and the fact he was in a non-contact jersey on Thursday helps his chances. Hill has become less attractive as a deep-league flex at RB since the return of second-year back Keaton Mitchell. Fantasy managers will most likely want to avoid Hill this week since he's most likely going to at least be questionable to play on Monday. If Hill doesn't get the green light to face the Bolts, rookie Rasheen Ali would be in line to be active behind Derrick Henry and Mitchell.

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Philadelphia Eagles quarterback Jalen Hurts (ankle) returned to full participation in Thursday's practice, as expected, after he was limited on Wednesday. Hurts tweaked his ankle a little bit a week ago in the win over the division-rival Washington Commanders and was receiving a little extra maintenance for it on Wednesday. The 26-year-old was never in any doubt to play in Week 12 against the Los Angeles Rams on Sunday Night Football and should remain locked into all starting fantasy lineups as a game-changing, elite QB1. Hurts will be looking for a bounce-back performance after running back Saquon Barkley stole the show last week. The Rams defense has been a plus matchup for opposing QBs in terms of fantasy points, although they have yet to allow a rushing TD to a QB all year. In the last six games, Hurts has thrown for eight TDs and one pick and has rushed for nine TDs.

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New York Giants rookie tight end Theo Johnson (back) was listed as a full participant in Thursday's practice after he went down as limited on the injury report on Wednesday. Johnson has been dealing with a back injury of late but didn't miss the Week 10 loss to the Carolina Panthers in Germany and had extra time to heal up during last week's bye. He had three catches for a season-high 51 yards and the first touchdown of his NFL career in the Week 9 loss to the division-rival Washington Commanders. Johnson has some intriguing long-term upside for those in dynasty/keeper leagues, but he hasn't really moved the needle as more of a TE3 in his first year in the league. The 23-year-old's fantasy stock in 2024 will likely be negatively affected by quarterback Daniel Jones' benching, as well as the impending return of receiver Darius Slayton (concussion).

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Tennessee Titans wide receiver Calvin Ridley (illness) returned to a full practice on Thursday after he sat out of the first practice of the week while being under the weather. Ridley is already feeling better and should be just fine to play this weekend against the division-rival Houston Texans on Sunday. The 29-year-old is Tennessee's unquestioned WR1 when healthy and he'll be looking to make a statement in the team's first meeting against the Texans in 2024. The matchup is a nice one, as the Texans defense is allowing the seventh-most half-PPR points per game (30.1) to receivers this season. Ridley should be treated as a low-end WR2/high-end WR3/flex in Week 12. Most of his production in his first year in Tennessee has come more recently, including his 143-yard performance and his two-touchdown day on Nov. 10.

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New York Giants wide receiver Darius Slayton (concussion) is stacking good days coming out of the bye week, practicing in full for the second straight day this week on Thursday. Slayton suffered a concussion in the Week 9 loss to the division-rival Washington Commanders and didn't travel to Germany the following week in the overtime loss to the Carolina Panthers. Last week's bye looks like it did Slayton some good, too, and he should be expected to return to the field this Sunday to take on the Tampa Bay Buccaneers. The 27-year-old should return to starting three-wide sets alongside rookie Malik Nabers and Wan'Dale Robinson, although now he'll be taking passes from quarterback Tommy Devito after Daniel Jones' benching. That's bad news for Slayton's fantasy upside, making him more of a WR5/flex in deeper leagues.

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Miami Dolphins wide receiver Tyreek Hill (wrist) upgraded to a full practice session on Thursday after being listed as a limited participant on Wednesday. Hill has been battling a wrist issue for most of the season but hasn't missed any games because of it. Now that he's back to full practice this week, the 30-year-old should be in the clear to play this Sunday against the division-rival New England Patriots. The five-time All-Pro wideout had a tough stretch in the middle of the season when quarterback Tua Tagovailoa was on Injured Reserve with a concussion, but he's now scored in back-to-back weeks, and his fantasy needle is pointing back upward. The Cheetah is a must-start for fantasy managers when he's active, including in Week 12. In the first meeting against the Pats on Oct. 6, Hill caught six of 10 targets (second time this year with double-digit targets) for 69 yards.

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Washington Commanders kicker Austin Seibert (hip) continued to practice in a limited capacity on Thursday. Fantasy managers should pay close attention to his status on Friday as it will likely clarify his availability heading into a divisional tilt against the Dallas Cowboys this Sunday. Seibert has been sidelined with this injury over the past two games. In his absence, Zane Gonzalez has taken starting duties. Before the injury, Seibert was enjoying a breakout campaign in the DMV. Since joining the Commanders in Week 2, Seibert has carried a stellar 92.6% rate on attempts and has gone perfect on extra points. If Seibert can return to action this weekend, fantasy managers should view him as a high-end kicking option facing a struggling Dallas defense.

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Detroit Lions tight end Sam LaPorta (shoulder) practiced in full for the second straight day this week on Thursday and appears to be on track to playing this Sunday against the Indianapolis Colts in Week 12. LaPorta suffered an AC joint sprain in his shoulder in the Week 10 win over the Houston Texans and was inactive in last Sunday's blowout win over the Jacksonville Jaguars. The 23-year-old appears to have healed nicely in the week he had to rest, and barring a setback on Friday, he should be able to play this Sunday at Lucas Oil Stadium. While LaPorta has mostly disappointed fantasy managers in 2024 after leading all TEs in fantasy points in his rookie season, he'll have an opportunity to produce strong numbers against a Colts defense that has allowed the sixth-most half-PPR points per game to the position this year.

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Dallas Cowboys tight end Jake Ferguson (concussion) did not take part in Thursday's practice. It's the second straight practice he has missed this week after suffering a concussion early in the Monday night loss to the Houston Texans in Week 11. The Cowboys said early this week that it's unlikely Ferguson will have enough time to clear the league's concussion protocol in time to play on Sunday against the division-rival Washington Commanders. The 25-year-old will most likely sit out Friday's session as well and be ruled out for this weekend. For those in dire need at the TE position in Week 12 with six teams on bye, Dallas' Luke Schoonmaker could be in play as a sleeper against Washington, a defense that allowed 12.7 half-PPR points per game to TEs the last three weeks. Schoonmaker had six catches for a season-high 56 yards on 10 targets against Houston on Monday after Ferguson was hurt.

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Minnesota Vikings quarterback Sam Darnold (foot) was upgraded to a full participant during Thursday's practice and is on track to play this Sunday against the Chicago Bears, according to Adam Schefter of ESPN. Fantasy managers should continue to monitor his status during Friday's practice in case he faces a setback. Darnold enjoyed a nice bounce-back showing this past weekend against the Tennessee Titans as he threw for 246 yards and two scores. This was a stark contrast to the poor showing he had in Week 10, where he tallied 241 yards with no scores and three interceptions. Overall, Darnold has enjoyed a great debut campaign in Minnesota as he has thrown 19 TDs and added one with his legs through 10 games. Fantasy managers should view him as a low-end QB1 this weekend, as he will face a tough Chicago defense that has allowed the second-fewest PPR points to opposing QBs this season.

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Kansas City Chiefs running back Isiah Pacheco (ankle) remained a limited participant during Thursday's practice. Fantasy managers should pay close attention to his status during Friday's practice as it may provide some clarity on his ability heading into the weekend. The Rutgers product has been sidelined since sustaining a fractured fibula in their Week 2 victory over the Cincinnati Bengals. While sidelined, veteran Kareem Hunt has seen most of the opportunities out of the backfield, with Samaje Perine and rookie Carson Steele mixing in. Before his injury, Pacheco was on track to enjoy a breakout campaign as he scored at least 15.0 PPR points in each game with at least 15 attempts and three targets in each contest. When he returns to action, fantasy managers should expect him to see most of the opportunities out of the backfield.

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Chicago Bears running back D'Andre Swift (groin) was upgraded to a limited participant during Thursday's practice after sitting out on Wednesday. Fantasy managers should continue to monitor his status during Friday's practice session, but this is a positive sign for his availability heading into the weekend. Last weekend, Swift enjoyed a nice bounce-back, scoring 16.4 PPR points after failing to hit double-digits during Week 10. Despite the offensive struggles the Bears have had this season, Swift has been a reliable option out of the backfield, averaging 18.3 PPR points during Weeks 4 through 11. If Swift can suit up this weekend, fantasy managers should view him as an RB2 despite the tough matchup against the Minnesota Vikings who have allowed the second-fewest PPR points to opposing RBs.

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