The San Francisco 49ers defense/special teams unit has a rough assignment in a Week 13 matchup against the Bills in Buffalo. San Francisco's defense is banged up entering Orchard Park with a significant snowstorm expected to stop just after kickoff. Lining up across from the Niners D will be Josh Allen and the NFL's 3rd-highest-scoring offense. Ruled out for Sunday are edge Nick Bosa (hip/oblique), defensive tackle Jordan Elliott (concussion), and nickel corner Deommodore Lenoir (knee). Linebacker Demetrius Flannigan-Fowles (knee) and rookie cornerback Renardo Green (neck) are questionable. Last week in Green Bay, the 49ers allowed 38 points to the Packers -- good for negative fantasy points in some leagues. They failed to secure any turnovers, got just two sacks, and are facing the distinct possibility of a repeat performance in Buffalo. San Francisco's reeling D/ST can be found all the way down at No. 24 in RotoBaller's Week 13 rankings.

From RotoBaller

New England Patriots kicker Joey Slye is not a reliable fantasy option heading into Sunday's Week 13 game against the Indianapolis Colts. The veteran has gone 19-for-23 on field goals and 16-for-17 on extra points this season, missing a 45-yarder last weekend. He has now missed a field goal in three of his last four games, demonstrating a lack of dependability in the middle portion of the 2024 season. Beyond Slye's unappealing ranking as the overall K22 this year, he faces a middle-of-the-road matchup this week in the form of the Colts, who have surrendered the 14th-most fantasy points to opposing kickers. The 28-year-old can be left on waivers in all fantasy leagues with 14 teams or fewer.

From RotoBaller

Pittsburgh Steelers kicker Chris Boswell will be looking to bounce back against the Cincinnati Bengals after missing one of his three field goal attempts in the snow last week. It was a rare miss for Boswell, who has been excellent for fantasy and arguably the best kicker in the NFL this season. While Cincinnati hasn't given up much production to kickers, the Bengals tend to get into high-scoring battles with most of the teams they face. Until Pittsburgh's offense proves it can punch the ball into the end zone consistently, Boswell will continue to be called upon frequently. The 10th-year veteran is a must-start fantasy asset with plenty of upside on Sunday.

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Pittsburgh Steelers tight end Pat Freiermuth showed signs of life for fantasy purposes last week and will look to stay involved in a Week 13 meeting with the Cincinnati Bengals. Cincinnati has given up plenty of production through the air this season and has allowed the fourth-most fantasy points per game to opposing tight ends. For what it's worth, Freiermuth has played quite well against the Bengals throughout his career and posted a career-high 120 receiving yards against them in Week 12 of the 2023 campaign. He is an intriguing fantasy streaming candidate in this matchup, but with no teams on bye this week, there are likely better options available for starting lineups.

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Pittsburgh Steelers running back Jaylen Warren had his best showing of the season in Week 12 and will carry some positive momentum into Sunday's meeting with the Cincinnati Bengals. The Bengals have been difficult to run on in 2024, allowing the 12th-fewest rushing yards to opposing backs. This contest is projected to be close and have a fair amount of points scored, however, so Warren should be utilized throughout as a weapon both on the ground and through the air. With Najee Harris still getting the bulk of the carries, Warren can't be confidently started as a top-24 option, but the 26-year-old offers some upside as a flex play this week.

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New England Patriots tight end Hunter Henry remains a reliable, top-12 fantasy option heading into Week 13 against the Indianapolis Colts. The veteran has been quite productive ever since Drake Maye took over as the Patriots' starting quarterback in Week 6, ranking as the overall TE10 in PPR leagues during that window. There's no indication that Henry will slow down soon, especially this Sunday against a Colts defense allowing the fourth-most yards, touchdowns, and fantasy points to opposing tight ends in 2024. The 29-year-old should be viewed as a mid-range fantasy TE1 this Sunday, and he also has a strong chance to score his first touchdown since Week 6 (and just his second touchdown of the season).

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Pittsburgh Steelers wide receiver George Pickens is earning nearly 30% of his team's targets and should once again serve as quarterback Russell Wilson's top option in a Week 13 clash with the Cincinnati Bengals. Pickens and the Steelers' offense struggled to get much going in the snow last week but could get back on track on Sunday. The Bengals surrender the 10th-most passing yards as well as the 12th-most fantasy points per contest to opposing wideouts. With Cincinnati scoring at such a high rate this season, Pittsburgh will likely need to air it out to keep up with their divisional rival. Pickens should be heavily involved this week and thus can be started in all fantasy formats as a low-end WR1.

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New England Patriots wide receiver Kayshon Boutte is tough to trust in fantasy football ahead of Week 13, but his large role on offense gives him some fantasy relevance in deeper leagues. The second-year pass-catcher has played at least 87 percent of the Patriots' offensive snaps in four consecutive weeks, totaling 11 catches and 104 yards during that span. He typically operates as a deep-threat option in New England, but he has had trouble hauling in big catches over the last few weeks. In fact, Boutte has been less productive than Kendrick Bourne and DeMario Douglas lately despite playing more snaps and running more routes. His deeper-league allure this week comes from the fact that the Colts have struggled to contain pass-catchers, allowing the eighth-most catches, seventh-most receiving yards, and 14th-most fantasy points to opposing wide receivers. Boutte ranks as a fringe top-50 fantasy wide receiver, earning WR4 consideration in most formats.

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New England Patriots wide receiver Kendrick Bourne will look to command at least five targets for the third consecutive game this Sunday against the Indianapolis Colts. The veteran receiver now has 10 targets, eight catches, 100 yards, and one touchdown over the last two weeks, ranking as the overall WR26 in half-PPR leagues during that span. While it's a small size and Bourne's production did decline from Week 11 to Week 12, it's still worth noting that he has quickly cemented himself as one of Maye's most preferred and reliable targets within the New England offense. He should continue to see heavy usage in Week 13, giving him WR3/FLEX appeal in leagues with at least 14 teams. His ranking could rise further if DeMario Douglas (ankle, questionable) isn't able to play this weekend. Bourne's opponent, Indianapolis, has allowed the eighth-most catches, seventh-most receiving yards, and 14th-most fantasy points to opposing wide receivers.

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San Francisco 49ers kicker Jake Moody is in Buffalo for a Week 13 matchup against the Bills. Since missing three field goals in his first game back from a multi-week ankle injury, Moody has been perfect, hitting two-of-two field goal attempts and all three extra-point tries. When confidence is high in San Francisco's offense, Moody is almost as good a fantasy choice as any, but this isn't one of those times. Buffalo's defense is decent, but the real problem is the state of the Niners' offense. Although quarterback Brock Purdy (shoulder) is expected to play, San Francisco's offensive line will be missing All-Pro left tackle Trent Williams and starting left guard Aaron Banks (concussion). Offensive weapons Christian McCaffrey and Deebo Samuel Sr. have been slumping and a cold, loud, possibly snowy Highmark Stadium isn't exactly the best get-right situation for the Niners -- or for Moody's accuracy for that matter. In most leagues, fantasy managers can do better than Moody in Week 13, doubly true if Purdy were held out again.

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After a hot stretch in the middle of the campaign, Pittsburgh Steelers running back Najee Harris has quieted down in recent weeks with fewer than 70 rushing yards in three straight contests. He could struggle again in Week 13 in a tough divisional matchup against the Cincinnati Bengals. The Bengals give up plenty of points to opposing teams but have been shutting down the running game for most of the season. It is worth noting, however, that Cincinnati has surrendered the fifth-most rushing touchdowns to running backs. With Jaylen Warren mixing in to split touches with Harris, it's difficult to project Harris for a lot of yardage on Sunday, so fantasy managers may be disappointed with his output unless he falls into the end zone. Because of this, Harris should be viewed as just a low-end RB2 in most formats.

From RotoBaller

Pittsburgh Steelers quarterback Russell Wilson has struggled over the past two weeks and will hope to bounce back against the Cincinnati Bengals in Week 13. In addition to surrendering the fifth-most points in the NFL, Cincinnati allows the third-most fantasy points per game to opposing quarterbacks. Although AFC North matchups involving Pittsburgh tend to be low-scoring defensive battles, this contest is projected for a healthy amount of points with a 47.5-point over/under. Wilson hasn't been consistent enough as a starter this season to warrant consideration in single-quarterback fantasy formats, but he is certainly a viable QB2 with upside in superflex leagues.

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New England Patriots running back Rhamondre Stevenson is coming off one of his worst games this season, as he rushed just eight times for 13 yards and failed to catch a pass last Sunday. Stevenson was inefficient, unproductive, and relatively uninvolved in the Patriots' loss to Miami. However, he has a chance to bounce back in a big way this week against the Indianapolis Colts. The Colts have struggled to slow down opposing backfields, allowing the eighth-most receptions, fourth-most rushing yards, and fourth-most fantasy points to running backs in 2024. The 26-year-old's fantasy ranking drops to the RB3 tier this week, but he's still worth deploying in most leagues given his favorable matchup at home.

From RotoBaller

New England Patriots quarterback Drake Maye remains an intriguing fantasy option ahead of Sunday's Week 13 game against the Indianapolis Colts. While Maye is coming off his second consecutive loss, the rookie has maintained solid fantasy production, ranking as the overall fantasy QB11 since he took over as the team's starter back in Week 6. This week, Maye gets one of his best matchups yet, facing a Colts defense that has allowed the third-most completions, fifth-most passing yards, and 12th-most fantasy points to opposing quarterbacks. This year's No. 3 overall pick ranks just inside the top 12 fantasy quarterbacks heading into this week's battle against an underperforming Colts squad.

From RotoBaller

If the San Francisco 49ers plan to knock off the Buffalo Bills in Orchard Park on Sunday night, the team will likely need tight end George Kittle to continue his run of production. In each game he's played since a disappointing Week 1, Kittle has outperformed half-PPR projections, culminating in last week's six-target, six reception, 90-yard, one-touchdown game in Green Bay. After spending all of 2023 as the epitome of a boom/bust fantasy asset, this season Kittle has flipped the script and become the 49ers' steadiest offensive producer. The Bills are the 13th-best in the league at limiting fantasy tight end half-PPR points per game. With starting quarterback Brock Purdy (shoulder) on the good side of questionable, San Francisco's offense still has an uphill battle as they'll be missing All-Pro left tackle Trent Williams (ankle) for the second-straight game and left guard Aaron Banks (concussion). A loud, cold, and maybe snowy environment will also make things tougher offensively. Kittle should considered a mid-high TE1 in Week 13, and a must-start even if Purdy can't go.

From RotoBaller

Tennessee Titans quarterback Will Levis is coming off arguably his best showing of the 2024-25 campaign, throwing for 278 yards, two touchdowns, and one pick in the Week 12 win over the Texans. He also completed 75% of his throws in that one. Although the signal-caller is beginning to show signs of life, he has a long way to go before he earns the trust of fantasy managers. With every team in the National Football League playing in Week 13, there are safer options available for fantasy managers. However, Levis is still worth considering for multi-QB fantasy setups in Week 13 versus the Washington Commanders.

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Tennessee Titans running back Tony Pollard is coming off one of his best performances of the season, amassing 119 yards and a touchdown off 24 carries, adding three catches for 10 yards in the win over the Houston Texans. After a few rough weeks, fantasy managers were certainly thrilled to see him turn things around. However, Pollard has had some uneventful showings during the 2024-25 campaign, so he's far from a sure thing from a fantasy standpoint. Still, the 27-year-old should be considered a starting fantasy option in nearly any fantasy format imaginable for the Week 13 matchup versus the Washington Commanders.

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Tennessee Titans wide receiver Nick Westbrook-Ikhine had a quiet start to the 2024-25 campaign. However, things have gone in a different direction, with the 27-year-old finding the end zone in six of his previous seven appearances. Granted, it would be nice if he had more catches, especially for those participating in PPR formats. Still, Westbrook-Ikhine appears to have a good thing going with Will Levis, so he warrants consideration for fantasy lineups. With that in mind, he's still a risky fantasy option in Week 13 versus the Commanders.

From RotoBaller

Buffalo Bills tight end Dawson Knox will be atop the depth chart on Sunday night when the team hosts the San Francisco 49ers. Starter Dalton Kincaid (knee) will be inactive for the second consecutive game. Knox logged a season-high mark in targets (six) and receptions (four) for 40 yards in place of Kincaid before the team's bye week. The 49ers are the sixth-best defense against fantasy football tight ends this season. With all 32 teams in action, Knox is outside of streaming consideration.

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Buffalo Bills running back Ray Davis has remained in a reserve role since Week 6 but holds value as a bench stash entering Week 13. The rookie only averaged five touches per game over the last four contests. If anything happens to starter James Cook, Davis would be the most valuable waiver-wire addition. Fantasy managers, especially those rostering Cook, can get ahead by adding Davis to benches. He should not be started against the San Francisco 49ers.

From RotoBaller