Indianapolis Colts wide receiver Josh Downs leads his team in targets (71) and yards per game (63.0). Quarterback Anthony Richardson looked his way five times in Week 11 and Downs caught all five balls for 84 yards and a touchdown. Coming into the contest with a 44.4% completion rate, there were concerns about Richardson's ability to get his receivers the ball, but he proved that he could still do it, even against a strong Jets pass defense (20-for-30, 66.7%). The Colts are seven-point underdogs for Sunday's contest against the Lions so there should be plenty of opportunities for Downs as the offense tries to keep pace with Detroit. With five catches in six of nine games played and the clear No. 1 receiver, the former third-round draft pick has a pretty reliable floor. The second-year pro sets up as a back-end WR2 this week with some small upside given his ability to find the zone (four TDs in 2024).

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San Francisco 49ers rookie wide receiver/kick returner Jacob Cowing (concussion) was unable to clear the league's concussion protocol and has been ruled out for Week 12 versus the Green Bay Packers. Cowing suffered his concussion in last Sunday's loss to the division-rival Seattle Seahawks and will now be hoping to clear the concussion protocol next week in order to face the Buffalo Bills in Week 13. Unexpectedly, the 23-year-old has mostly factored in on special teams (returning punts) in his first year in the NFL, despite Brandon Aiyuk (knee) being lost for the season. In nine games in 2024, the Arizona product only has two receptions on three targets for 50 yards. With Cowing out of action this Sunday at Lambeau Field, Ronnie Bell will most likely serve as the team's punt returner.

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Green Bay Packers wide receiver Christian Watson is looking to build off the best game of his 2024 season as the Packers host the San Francisco 49ers in Week 12. Watson amassed four receptions and 150 receiving yards and was hugely efficient for the Packers in their win over the Chicago Bears in Week 11. Besides that outburst, Watson has been kept relatively in check by defenses and hasn't been given a full complement of snaps and routes as he's rotated with Dontayvion Wicks and Jayden Reed at times. Still, Watson hasn't been able to make the most of his opportunities, which makes him a volatile fantasy asset to start. That puts Watson squarely into flex territory in a tough matchup with the 49ers in Week 12.

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Green Bay Packers wide receiver Romeo Doubs has had a tough go of things over the last couple of weeks, but he looks to right the ship as the Packers square off with the visiting San Francisco 49ers in Week 12. Despite running the most routes per dropback each week for the Packers, Doubs hasn't had the production come with that time on the field as he has just seven targets, five receptions, and 45 receiving yards in his last two games. It hasn't been as fruitful of a time for the Packers' passing game as quarterback Jordan Love hasn't thrown for multiple touchdown passes in his last three games. With Doubs' falling production and the stingy 49ers pass defense set to take on the Packers, Doubs should be considered a mid-range flex play at best with a lower ceiling and a somewhat-shaky floor.

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Houston Texans quarterback C.J. Stroud should mostly be kept to Superflex duty as his team takes on the solid Tennessee Titans defense in Week 12. The Ohio State product has had an up-and-down second season, ranking a disappointing 17th among fantasy quarterbacks after his breakout rookie campaign. Part of the struggle has been pass protection, as Houston has allowed the third-most sacks in the league. Tennessee, despite its 2-8 record, has allowed the fewest air yards in the league and has been a competent defense. Stroud has his top playmaker back in receiver Nico Collins, but with this matchup, managers in 1QB formats should be weighing their other possible options.

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The San Francisco 49ers will be without starting quarterback Brock Purdy (shoulder) in Week 12 against the Green Bay Packers at Lambeau Field, and they could also be without starting left tackle Trent Williams (ankle), as he's listed as questionable for Sunday's game. Williams played through the ankle injury in the Week 11 loss to the division-rival Seattle Seahawks and was pretty sore following the game. The 36-year-old has yet to miss a game in 2024, but the Niners may be forced to sit him out to let his ankle heal heading into next week's showdown against the Buffalo Bills. The Niners' offense will already be facing a serious downgrade with Brandon Allen starting under center, and things could get worse if they don't have Williams at left tackle. The Packers' defense/special teams unit will be a sneaky streaming option this weekend.

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Indianapolis Colts running back Jonathan Taylor was held to under 100 total yards rushing and receiving last Sunday for the second time in three weeks. While Week 12's showdown with the Lions looks like another tough matchup on paper, with the Lions allowing the fifth-fewest rushing yards per game thus far and the fourth-fewest fantasy points to running backs, if the Colts wish to keep this game close then they will have to run the ball to kill the clock and limit Detroit's opportunities, which in turn should benefit the 25-year-old. If the game gets out of reach, however, the Colts will find themselves in catch-up mode using the passing game, which Taylor has not been heavily involved in to this point, averaging less than two receptions per game for less than 14 yards per contest. Nevertheless, the talented former second-round draft pick projects as a back-end RB1 this week.

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Houston Texans tight end Dalton Schultz will face the struggling Tennessee Titans in Week 12, though that's not good news for a mid-tier fantasy player at his position. The Titans' solid defense has been particularly good against fantasy tight ends, ranking sixth overall and holding Minnesota's T.J. Hockenson to just two catches for 13 yards in a loss to the Vikings last week. Schultz now hasn't scored a regular-season touchdown in a calendar year and ranks 23rd among tight ends in PPR formats. Bye weeks are wreaking havoc on lineups, but fantasy managers should aim higher than Schultz's typical TE2 output if they have other options.

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The Green Bay Packers defense and special teams unit got a bit of an upgrade and should now be considered a pretty good option in fantasy lineups as the Packers host the San Francisco 49ers in Week 12. The 49ers will be without quarterback Brock Purdy (shoulder) as he was ruled out of Sunday's matchup due to a shoulder injury. Journeyman backup Brandon Allen will get the nod for the suddenly reeling 49ers who are looking to crawl out of a 5-5 hole on the season to reach the playoffs in the NFC. For the Packers, their defense hasn't been great over the last four games, but their three-sack and a blocked kick against the Chicago Bears were good enough to place in the top-ten for fantasy defenses. With Allen in at quarterback on the road at Lambeau Field, the Packers should get a solid upgrade to become plenty startable in Week 12.

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The Tennessee Titans present a difficult matchup for Houston Texans wide receiver Tank Dell in their first meeting of the season in Week 12. The Titans' brutal offense has dragged down the team's record, but their defense ranks an impressive second overall against fantasy wide receivers through 11 weeks. That presents a complicated decision for fantasy managers who roster the second-year Texan, who is once again playing second fiddle to teammate Nico Collins and dependent on a shaky Houston offensive line that has struggled to limit sacks at times. Dell is averaging 8.3 targets over his past three games, but the risk involved with the Week 12 matchup relegates him to a WR3/Flex play.

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Baltimore Ravens running back Justice Hill (concussion) was able to practice in full on Friday after being limited on Thursday. Hill suffered a concussion in the Week 11 loss to the division-rival Pittsburgh Steelers and is working through the league's concussion protocol. It's a good sign that he ditched his non-contact jersey on Friday, but Hill still needs to gain clearance from an independent neurologist in order to get the green light to play on Monday night versus the Los Angeles Chargers. If Hill is cleared in time to play on Monday, he'll be a low-upside RB3/flex, at best, in point-per-reception leagues. His opportunities out of Baltimore's backfield could be more sparse down the stretch as second-year back Keaton Mitchell gets more involved. If Hill isn't cleared by an independent neurologist, Mitchell and rookie Rasheen Ali would be backing up Derrick Henry against the Bolts.

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Back in the lineup after a prolonged absence, Houston Texans wide receiver Nico Collins is once again a top fantasy option as his team takes on the Tennessee Titans in Week 12. The Michigan Man had only four catches last week against Dallas, but he also played only 47% of Houston's offensive snaps in the 34-10 win. The Titans, however, are a much tougher defensive matchup. Tennessee has given up the fewest air yards in the NFL so far this season and ranks second against fantasy wide receivers. Even so, Collins is among the elite tier of wide receivers who ought to be started even against top opponents, and this week is no exception.

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Already one of the top-performing fantasy players of the year, Houston Texans running back Joe Mixon faces another decent matchup when his team plays host to the Tennessee Titans in Week 12. The top Houston back has scored in six straight games and rushed for 100-plus yards in five of six, and now takes on a Tennessee team that ranks 17th against fantasy running backs. The Texans are giving Mixon a feature back workload with nearly four red zone touches and 2.5 targets per game, making him a dynamic RB1 option in any format. He should be starting once again in Week 12.

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Green Bay Packers tight end Tucker Kraft looks to get out of his production slump as the Packers host the San Francisco 49ers in Week 12. If you've started Kraft in fantasy football over the past couple of weeks, you've no doubt been disappointed. Just before the Packers' bye in Week 10, Kraft was held to four catches for 34 yards on six targets. Last week after the team's bye, Kraft was completely stymied with just one target and no catches. The Packers' offense has been in a funk lately with quarterback Jordan Love not throwing for double-digit touchdowns in the last three games. With the Packers set to tangle with a tough pass defense in the 49ers, Kraft is in the streaming category of fantasy tight ends this week, where you're hoping for a touchdown to make starting him worth it.

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Baltimore Ravens wide receiver Rashod Bateman (knee) was added to the Week 12 injury report on Friday and was listed as a non-participant. Mid-week additions to the injury report are usually not good, but Bateman has one more day to get back on the practice field before the Ravens release their final injury report on Saturday for Monday night's game against the Los Angeles Chargers. If the 24-year-old's injury is serious enough to keep him sidelined in Week 12, it could be an opportunity for the recently acquired Diontae Johnson to finally get more involved in the offense next to Zay Flowers and Nelson Agholor (illness). Bateman was held quiet in the Week 11 loss to the division-rival Pittsburgh Steelers, but he's quietly had a career year in his fourth year in Baltimore, catching 33 passes for 531 yards and four touchdowns in 11 games.

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Kicker Ka'imi Fairbarin of the Houston Texans remains a clear starter once again as his team prepares to take on the slumping Tennessee Titans in Week 12. The longtime Texans kicker has logged at least two made field goals in seven consecutive games, and nobody in the NFL has made more kicks from beyond 50 yards this season. Nine of his 11 kicks from 50-plus yards were indoors, and the Texans find themselves playing their first of two matchups with the Titans at home this week. At this point, Fairbairn is an every-game starter while attached to a talented Houston offense.

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San Francisco 49ers tight end George Kittle (hamstring) was removed from the final injury report on Friday and will be active for the Week 12 game on Sunday against the hosting Green Bay Packers. Hamstring irritation caused Kittle to miss the Week 11 loss to the division-rival Seattle Seahawks, but he'll end his absence at just one game and return this weekend at Lambeau Field. Fantasy managers' excitement will be tempered for the 31-year-old, though, with quarterback Brock Purdy (shoulder) being ruled out for Week 12. While Kittle remains a must-start in all fantasy lineups, DFS managers will probably want to avoid him with Brandon Allen throwing him passes this weekend on the road. Despite missing two games due to injury in 2024, Kittle is the TE2 in overall fantasy points, trailing only rookie Brock Bowers of the Raiders.

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Indianapolis Colts quarterback Anthony Richardson is coming off his best fantasy performance since Week 1 after accounting for three touchdowns in Week 11. In Week 12, the Colts draw the Lions and they will be seven-point home underdogs in a game that features a high expected total (50). Although the 22-year-old completed 67% of his passes last week, he still has just a 48.5% completion rate for the season, so Indy would prefer to not have to play catch-up all day through the air. Look for the Colts to attempt to keep the ball out of Jared Goff's hands by sticking to the run for as long as possible, as difficult a task as that may be against a rush defense that has allowed the fifth-fewest rush yards per game this season. Still, Richardson should have a decent floor with his rushing ability and has a decent chance to score if they get down close. View the former first-round draft pick as a high-end QB2, with his rushing ability giving him QB1 upside this week.

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Despite practicing in full all week, the Denver Broncos ruled wide receiver Josh Reynolds (hand) out for Week 12 against the division-rival Las Vegas Raiders on Sunday. Although Reynolds is getting close to making his return, he'll remain on Injured Reserve for another week. The 29-year-old's next chance to play for the Broncos will be in Week 13 against the Cleveland Browns on Monday Night Football. In addition to landing on IR with a hand injury, Reynolds was shot multiple times in an off-the-field incident. Those injuries apparently aren't holding him back at all. When Reynolds does return, he'll be battling for targets behind Courtland Sutton with rookies Devaughn Vele and Troy Franklin and Lil'Jordan Humphrey. Denver's offense is peaking right now, but it's still hard to envision Reynolds having a consistent enough role to warrant fantasy attention in 12-team leagues.

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Washington Commanders tight end Zach Ertz should continue to be viewed as a low-end TE1 in Week 12 when he faces the Dallas Cowboys. Last week, during their loss to the Philadelphia Eagles, Ertz brought in six of his seven targets for 47 yards and his second touchdown of the season. Since Week 6, Ertz has scored double-digit PPR points in four of the six contests and averaged 6.2 targets per game in this span. With a lack of a proven No.2 option in the passing attack, Ertz has continued to see a steady volume of work weekly. Fantasy managers in deeper formats should continue to view Ertz as a solid option this weekend when facing a struggling Cowboys defense that has allowed 34 points in each of their past two games.

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