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Denver Broncos running back Jaleel McLaughlin is a healthy scratch for his team's Week 2 game against the Indianapolis Colts. McLaughlin was also inactive in Week 1, so this decision from the team does not necessarily come as a surprise. Without McLaughlin, Denver will roll with the running back trio of J.K. Dobbins, RJ Harvey, and Tyler Badie.

From RotoBaller

Cincinnati Bengals quarterback Joe Burrow (toe) is questionable to return to his team's Week 2 matchup against the Jacksonville Jaguars due to a toe injury, per Ian Rapoport of NFL.com. Burrow was taken into the locker room with assistance from trainers and was limping heavily. It remains to be seen whether Burrow will be able to return on Sunday, but the fact that he was not immediately ruled out by the team has to be considered a positive sign.

From RotoBaller

Detroit Lions tight end Shane Zylstra (ankle) has been downgraded to out for the remainder of his team's Week 2 contest against the Chicago Bears. Zylstra is the Lions' third-string tight end behind Sam LaPorta and Brock Wright. His absence may mean a slight uptick in snaps for the remainder of Week 2 for LaPorta.

From RotoBaller

Cincinnati Bengals quarterback Joe Burrow (leg) was taken to the locker room on Sunday due to an apparent left leg injury. Burrow was limping heavily and required assistance from the training staff to get off the field. More will be known about the injury once the team releases an official update, but a Burrow injury would obviously be a massive blow for both fantasy managers and the Bengals' offense.

From RotoBaller

The Cleveland Browns announced that wide receiver DeAndre Carter (concussion) will not return to Sunday's game against Baltimore due to the injury. The veteran made the team out of training camp largely because of his special teams contributions. Primarily the team's kick returner, the absence will leave Cleveland without one of its key special teamers for the rest of the game.

From RotoBaller

San Francisco 49ers fullback Kyle Juszczyk (concussion) has been ruled out for the remainder of his team's Week 2 game against the New Orleans Saints. Juszczyk is a key piece of the San Francisco offense as both a blocker and receiver. The 49ers entered the game already without quarterback Brock Purdy (toe), tight end George Kittle (hamstring), and wide receiver Brandon Aiyuk (knee). Juszczyk's absence may create even more reason for San Francisco to get the ball in the hands of star running back Christian McCaffrey.

From RotoBaller

The Buffalo Bills can exhale after quarterback Josh Allen (nose) has returned to the game against the New York Jets after taking a shot to the face. The superstar QB departed the game after being bloodied when he was sandwiched between two Jets defenders, a collision that popped him in the nose. Allen wasn't out for long, though, as the Bills' medical staff put gauze up one nostril and got back him on the field. Fantasy managers rostering the QB1 can forge ahead as usual.

From RotoBaller

The Baltimore Ravens have ruled out running back Rasheen Ali (concussion) from returning to Sunday's game against the Cleveland Browns. A key special teamer for the Ravens will be out of the picture for at least the rest of this week. Additionally, Baltimore did not activate running back Keaton Mitchell ahead of the game, so the club has only its top two running backs, Derrick Henry and Justice Hill, available for the remainder of Sunday.

From RotoBaller

The Detroit Lions said tight end Shane Zylstra (ankle) is questionable to return to the game Sunday against the Chicago Bears. The reserve came off the field with a bit of a limp after sustaining the injury, which could leave the Lions without a key special teamer. From a fantasy perspective, Zylstra is pretty far off the radar with starting tight end Sam LaPorta handling the vast majority of the receiving work.

From RotoBaller

Baltimore Ravens running back Rasheen Ali (concussion) is being further evaluated after taking a blow to the head on Sunday against the Cleveland Browns, the team announced. Ravens running back Keaton Mitchell is inactive again for Baltimore, so the team is temporarily down to just Derrick Henry and Justice Hill at running back. Ali, also a special teamer for the Ravens, is mostly on the back burner from a fantasy perspective due to a lack of carries behind Henry and quarterback in Lamar Jackson.

From RotoBaller

The Cleveland Browns said wide receiver DeAndre Carter (concussion) left Sunday's game against the Baltimore Ravens to be evaluated in the locker room. The veteran does not have a target yet this season, as his primary role for Cleveland is to be a return man, so the Browns likely will have to look elsewhere if he misses any time. In any case, Carter doesn't hold much fantasy value outside of leagues of that have a designated kick returner spot.

From RotoBaller

San Francisco 49ers wide receiver Jordan Watkins (coach's decision) and running back Jordan James (coach's decision) are both healthy scratches for Week 2 against the New Orleans Saints. Watkins and James both missed last week's season opener, and even though they're healthy for Week 2, the rookies will watch Sunday's game from the sideline. Kendrick Bourne, Marquez Valdes-Scantling, and Skyy Moore will round out the wide receiver room behind Jauan Jennings and Ricky Pearsall. Meanwhile, Isaac Guerendo will handle RB3 duties behind Christian McCaffrey and Brian Robinson Jr.

From RotoBaller

According to CBS Sports, Cleveland Browns rookie second-round running back Quinshon Judkins will start in his NFL debut in Week 2 against the Baltimore Ravens. Judkins may get the "start," but NFL Network's Ian Rapoport also reported on Sunday morning that the Browns plan to give Judkins backup touches -- around 10 to 15 in his first NFL game. Fantasy managers will be happy to get a look at the Ohio State product, but it would be a mistake to throw him into your starting lineup right away with the Browns easing him into their offense after he missed all of training camp, the preseason, and the Week 1 loss to the Cincinnati Bengals. Judkins should be Cleveland's RB1 by season's end, but it won't be right away, and he could also be facing a suspension of two to four games after a domestic-violence case over the summer.

From RotoBaller

New York Jets wide receiver Allen Lazard will make his 2025 debut in Week 2 against the division-rival Buffalo Bills on Sunday after he was a healthy scratch in the season-opening loss last Sunday to the Pittsburgh Steelers. Lazard might only be active because Josh Reynolds is out with a hamstring injury. Although it's notable for New York's passing attack, we wouldn't recommend the 29-year-old as a streaming option this weekend, even in deep fantasy leagues. Garrett Wilson will continue to draw the majority of aerial targets from quarterback Justin Fields. Lazard, who has struggled with drops in his two seasons with the Jets, will be competing for targets with Tyler Johnson mostly. Last year in New York, Lazard bounced back from a rough 2023 campaign to catch 37 passes for 530 yards and six touchdowns in 12 games (10 starts).

From RotoBaller

The Philadelphia Eagles are "looking to get A.J. Brown involved more and early" on Sunday against the Kansas City Chiefs, according to NFL Network's Mike Garafolo. He noted that the Eagles had several plays dialed up for Brown to get more targets last week, but they didn't work out, and the star receiver finished Week 1 with just one reception. Based on Garafolo's comments, it appears that last week should be treated as an anomaly, and Brown will be more involved in Week 2. An increased target share could come naturally for Brown as the Eagles will be without Dallas Goedert (knee), who caught seven passes in the season opener.

From RotoBaller

Baltimore Ravens running back Keaton Mitchell finds himself as a healthy inactive for the second straight week to open the season in Week 2 against the division-rival Cleveland Browns on Sunday. To begin the 2025 campaign, Mitchell has found himself as the team's RB4 behind Derrick Henry, Justice Hill, and Rasheen Ali. The 23-year-old has intriguing power and explosiveness, but he's had trouble staying on the field early in his career, playing only 13 games (two starts) since entering the league in 2023. He has averaged a healthy 6.9 yards per carry on his 62 rushing attempts with 426 yards and two touchdowns, but right now, he's off the fantasy radar altogether in redraft leagues. Mitchell's next chance to make his 2025 debut will be in Week 3 against the Detroit Lions on Monday, Sept. 22.

From RotoBaller

New York Jets rookie tight end Mason Taylor (ankle) is officially active and will play on Sunday against the division-rival Buffalo Bills at MetLife Stadium. Taylor was listed as questionable on the final Week 2 injury report, but he will be available for the Jets and fantasy managers. The 21-year-old second-rounder played 88 percent of the offensive snaps in the Week 1 loss to the Pittsburgh Steelers, but he only had one catch (on one target) for 20 yards, despite the team putting up 30 points. He'll be looking to increase his production against a Bills defense that just gave up 40 points to the Baltimore Ravens in Week 1, although Ravens tight end Mark Andrews only had one catch for five yards. Fantasy managers should consider Taylor more of a TE3 on Sunday in just his second NFL game.

From RotoBaller

Miami Dolphins running back Jaylen Wright (knee), who was listed as doubtful on Friday's final injury report, is officially out for Sunday's Week 2 divisional clash against the New England Patriots. Wright had a minor surgery on his right knee in late August and was always expected to miss time early in the 2025 season. With a quick turnaround next Thursday night in another divisional tilt against the Buffalo Bills, Wright is probably going to be facing an uphill battle to make his season debut. When fully healthy, the explosive and fast Wright should operate as De'Von Achane's primary backup. Miami's offense looked terrible in the Week 1 loss to the Indianapolis Colts, giving rookie Ollie Gordon II limited opportunities to make noise behind Achane. Fantasy managers should not be starting Gordon against the Pats with Wright out again.

From RotoBaller

Buffalo Bills veteran wide receiver Curtis Samuel is once again a healthy inactive for Sunday's Week 2 divisional contest on the road against the New York Jets. Samuel was also a healthy scratch for the season-opening win over the Baltimore Ravens last Sunday night. Right now, the 29-year-old is buried on Buffalo's receiver depth chart, thanks to the offseason additions of Joshua Palmer and Elijah Moore. Khalil Shakir, Keon Coleman, and Tyrell Shavers are also ahead of him. Samuel should remain on the waiver wire in all fantasy formats for now. In his first year with Buffalo in 2024, he caught 31 of his 46 targets for 253 yards and only one touchdown in 14 regular-season games (two starts).

From RotoBaller

The Chicago Bears have declared DE Shemar Turner, OT Ozzy Trapilo, QB Case Keenum, OT Kiran Amegadjie, WR Jahdae Walker and CB Kyler Gordon inactive for Week 2.

From TheHuddle