Sources are saying that Jacksonville Jaguars quarterback Trevor Lawrence (shoulder) is considered unlikely to play in Week 10 against the visiting Minnesota Vikings on Sunday as he continues to get treatment and weight options for the future due to a left-shoulder injury. Lawrence was limited in the team's first practice of the week on Wednesday, and head coach Doug Pederson was non-committal about his status for the weekend. This comes as a bit of a surprise with the 25-year-old dealing with a sore non-throwing shoulder. We'll know more on Lawrence's Week 10 status on Friday, but for now, fantasy managers should move him to their benches. Jacksonville added C.J. Beathard for QB depth on Tuesday, but backup Mac Jones will likely make his first start of 2024 if Lawrence is inactive. Jones will only be worth looking at as a desperation low-end QB2 option in superflex fantasy leagues.

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Tampa Bay Buccaneers quarterback Baker Mayfield (toe) will miss a second straight practice this week on Thursday, but sources are saying he will be fine to play in Week 10 against the San Francisco 49ers. Mayfield apparently picked up a toe injury despite playing all of the Monday night overtime loss to the Kansas City Chiefs. The 29-year-old will likely return to practice in some capacity on Friday and will be active this Sunday as the team hosts the 49ers, who are coming off their bye. Without receivers Mike Evans (hamstring) and Chris Godwin (ankle) and with rookie Jalen McMillan (hamstring) and Sterling Shepard (hamstring, hip) also banged up, Mayfield could be operating this weekend with Trey Palmer as his No. 1 wideout. He's been leaning heavily on tight end Cade Otton in recent weeks. With how thin Tampa's receiving corps is right now, Mayfield will be a much shakier QB1 streaming option in fantasy.

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Cincinnati Bengals running back Zack Moss (neck) will meet with neck specialist Dr. Robert Watkins and is likely to avoid surgery. It's good news for Moss, but he's already been placed on Injured Reserve and will miss the rest of the 2024 season after injuring his next in the Week 9 win over the Las Vegas Raiders. He will be shut down for the next two months. In a best-case scenario, the 26-year-old might be able to return if the Bengals make the postseason and make a deep run. In his first year in Cincy, Moss finishes with 74 carries for 242 yards (career-low-tying 3.3 yards per carry) and two touchdowns while snagging 23 of his 27 targets for 187 more yards and a touchdown. The Bengals quickly replaced Moss by trading for Bears RB Khalil Herbert, who should immediately serve as the No. 2 behind Chase Brown, possibly as early as Thursday night against the division-rival Baltimore Ravens.

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Green Bay Packers general manager Brian Gutekunst said that rookie running back MarShawn Lloyd (ankle) is going to be ready to be activated from Injured Reserve in the near future and will likely take the 53-man roster spot of linebacker Preston Smith, who was dealt to the Pittsburgh Steelers on Tuesday at the trade deadline. The Packers are on bye in Week 10, but they could open the 23-year-old's 21-day practice window next week, and he could be ready to return for a Week 11 clash against the division-rival Chicago Bears. The third-rounder has been banged up since training camp and only played in Week 2 against the Colts, carrying the ball six times for 15 yards and catching one pass for three yards. Lloyd has missed a lot of developmental time in his rookie campaign, but he has the skills to be Green Bay's RB2 behind Josh Jacobs by season's end.

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The Carolina Panthers an star running back Chuba Hubbard agreed on a four-year, $33.2 million contract extension on Thursday, according to sources. Hubbard receives a maximum value of $37.2 million with $15 million in new fully guaranteed money. The 25-year-old former fourth-round pick in 2021 out of Oklahoma State took over lead-back duties from Miles Sanders a season ago and hasn't looked good. While he could loses valuable touches in the backfield to rookie Jonathon Brooks (knee), who is trending toward making his NFL debut in Week 10, the rest of the way, Hubbard should remain the Panthers' top option after averaging 5.0 yards per carry through nine games in 2024. Hubbard currently ranks as the RB7 in half-PPR fantasy scoring heading into Week 10 in Germany against the New York Giants, where he should be deployed as an RB2.

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NFL Network's Mike Garafolo reports that there is optimism that Baltimore Ravens running back Keaton Mitchell (knee) will be active for Thursday night against the division-rival Cincinnati Bengals to kick off Week 10 action. Head coach John Harbaugh said earlier this week there was a chance Mitchell would be activated from the Physically Unable to Perform list to make his 2024 debut on Thursday, and it looks like it's going to happen after he put in three full practices from Monday through Wednesday. The explosive second-year back won't be recommended for starting fantasy lineups in his first game back, but don't forget that he averaged 8.4 yards per carry and also 10.3 yards per reception in his first eight games in 2023 before tearing his ACL. Mitchell's impending return is bad news for Justice Hill, but Derrick Henry will remain Baltimore's unquestioned lead back.

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The San Francisco 49ers signed free-agent S Tashaun Gipson (Jaguars) to the practice squad on Wednesday, Nov. 6.

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Updating previous reports, Dallas Cowboys QB Dak Prescott (hamstring) could require surgery on the partial avulsion of his hamstring, per The Dallas Morning News' Calvin Watkins, who says that team officials are trying to determine whether the portion of the tendon that tore off the bone will heal on its own. If Prescott, who is currently seeking additional opinions, does end up needing the surgery, he will miss the remainder of the 2024 season.

Fantasy Spin: Things remain up in the air regarding Prescott's status. A move to IR would cost him at least four games, and now the possibility of the injury being season-ending is out there. Nothing has been decided yet as he gathers more input on the injury, but things don't seem to be trending in a positive direction. If you own Prescott, you should hold him at least until the full extent of the injury (and corresponding timeline for his possible recovery) are determined.

From TheHuddle

Baltimore Ravens running backs Keaton Mitchell (knee) and Rasheen Ali (ankle) are both listed as questionable for the team's Thursday night matchup against the Cincinnati Bengals. Mitchell has been working through a knee injury, and if he's active, it will be for the first time this season. Ali has been dealing with an injury of his own that's kept him out of Baltimore's prior three contests. It would be fantastic if the duo could return to full health, but with teammates Derrick, Henry, and Justice Hill in clear, defined roles in the Ravens' offense, there aren't many excess touches to go around. Neither Mitchell nor Ali will be recommended fantasy options if they're active for the Week 10 outing.

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Per New York Giants head coach Brian Daboll, wide receiver Darius Slayton (concussion) was tagged with a DNP Wednesday and might not travel with the team to Germany. Pat Leonard of NYDN Sports reported the news. Slayton sustained a concussion late in the Giants' 27-22 loss to the Washington commanders in Week 9. It's unfortunate news for the sixth-year wideout, who has been a valuable deep threat for New York this season. Second-year wide receiver Jalin Hyatt figures to take over some snaps if the former Auburn Tiger can't clear the league's concussion protocol, with Ihmir Smith-Marsette working in behind him. Fellow WRs Malik Nabers and Wan'Dale Robinson project to see an uptick in usage absence.

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Tennessee Titans wide receiver Tyler Boyd (shoulder) was officially listed as limited for his team's first practice of the week. Boyd was knocked out of Sunday's 20-17 victory over the New England Patriots after participating in just 22 snaps, so it's excellent to see him at least get in a limited session ahead of Week 10. With an afternoon road matchup against the Los Angeles Chargers on tap, the veteran wideout will be afforded a slightly larger window to regain his health. If the long-time Cincinnati Bengal can't suit up, rookie wide receiver and kick returner Jha'Quan Jackson again projects to pick up the slack in Tennessee's WR corps.

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The San Francisco 49ers signed free-agent WR Russell Gage Jr. (Ravens) to the practice squad and released WR Malik Turner from the practice squad Wednesday, Nov. 6.

From TheHuddle

Cincinnati Bengals wide receiver Ja'Marr Chase had seven catches in the win over the Raiders. However, he totaled only 43 yards. But fantasy managers should be willing to give the wideout a pass on that performance, considering he had seven touchdowns in the six games leading up to Week 9. With an NFC North meeting with the Ravens on tap, everyone remembers Chase's 10-catch, 193-yard, two-touchdown showing when these clubs last met in Week 5. Keep him rolling in all fantasy formats, although that goes without saying.

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Tennessee Titans quarterback Will Levis (shoulder) was again listed as limited for the team's Wednesday practice. Levis has been a limited participant for eight straight practices, and his status for Sunday's game against the Los Angeles Chargers is unclear as he works through a shoulder injury that has kept him out of action since Week 6. He'll have two more opportunities to elevate his practice status ahead of Week 10's outing, but if he can't go, it will again be quarterback Mason Rudolph manning the helm for Tennessee. The Titans have let Rudolph air it out while he's been under center, averaging 37 pass attempts per game while working to a 1-2 record and a 4:4 TD:INT ratio.

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Cincinnati Bengals wide receiver Andrei Iosivas had only one reception in the Week 9 win over the Raiders. However, it at least resulted in a trip to the end zone. With Tee Higgins (quadriceps) unlikely to suit up on Thursday night versus the Ravens, Ja'Marr Chase should continue to get extra attention from Joe Burrow. Although Iosivas could also benefit, he's hard to trust despite the favorable matchup on the horizon.

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Cincinnati Bengals tight end Mike Gesicki has been on a roll of late. After amassing seven grabs in the Week 8 loss to the Eagles, the 29-year-old had five catches for 100 yards and two touchdowns in Sunday's win over the Raiders. With that in mind, Gesicki has had issues staying consistent through the years, so he's hard to trust on Thursday night versus the Ravens, even if Tee Higgins (quadriceps) remains on the shelf. Still, Gesicki has a place in multi-tight end setups in a favorable matchup against a subpar Ravens defense.

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Cincinnati Bengals quarterback Joe Burrow will meet the Ravens for the second time this season. The signal-caller is coming off a strong showing, throwing for 251 yards off 27-for-39 passing in Week 9 versus the Raiders. He also tossed five touchdowns, the same number he had in the narrow overtime loss to Baltimore in Week 5. Granted, it will be difficult to duplicate such a performance, even against a shaky Ravens defense. However, the upside is there for Burrow, giving him a favorable outlook for Week 10.

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Cincinnati Bengals running back Chase Brown had a stellar showing in the Week 9 win over the Las Vegas Raiders. He ran the ball 27 times, amassing 120 yards and adding 31 yards off five catches, one of which resulted in a touchdown. With Zack Moss (neck) done for the remainder of the 2024-25 campaign, Brown should see more action moving forward. Keep him starting in Week 10 versus an unreliable Ravens defense.

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Tennessee Titans running backs Tony Pollard (foot) and Tyjae Spears (hamstring) were both listed as limited participants in Tennessee's first practice ahead of Week 10. Pollard has dealt with a foot issue for some time but was productive again in last Sunday's 20-17 victory over the New England Patriots and has yet to miss any time this season. On the other hand, Spears is hoping to return from a three-game absence after battling a hamstring injury for the last few contests. Word came out earlier this week that the Titans are looking to reduce the veteran's workload. If Spears is again inactive, backfield mate Julius Chestnut could be on tap for an increased share of the backfield touches this coming Sunday when Tennessee squares off against the Los Angeles Chargers on the road at SoFi Stadium.

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Arizona Cardinals running back James Conner (finger) was listed as a limited participant in the team's first practice of the week. Conner left Arizona's 29-9 win against Chicago on Sunday, but the finger issue is new for the 29-year-old. That he was limited is good news, but fantasy managers should keep an eye on his status over the next few days. It might behoove Conner owners to tentatively scoop up rookie running back Trey Benson or second-year back Emari Demercado in anticipation of the veteran missing time. Both athletes split snaps pretty evenly in Conner's stead in Week 9's victory. The Cardinals get a tough matchup against a stout New York Jets front seven on Sunday in Week 10.

From RotoBaller