Cincinnati Bengals wide receiver Andrei Iosivas found the end zone four times as a rookie. As a result, many expect him to get more involved in the offense this season, especially with Tyler Boyd no longer on the roster. However, his level of involvement could increase even more in the Week 1 matchup with the New England Patriots. Ja'Marr Chase (not injury-related) and Tee Higgins (hamstring) aren't a lock to suit up. If that's the case, Joe Burrow (wrist) could look in Iosivas' direction more than initially anticipated, potentially giving him value as a flex option in deeper fantasy setups. But first, Chase and Higgins will officially need to be ruled out.

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Cincinnati Bengals wide receiver Jermaine Burton (toe) scored twice in the preseason. Yet, it's logical to assume it will still take him at least a year or two before he's consistently relevant for fantasy managers. With that said, Ja'Marr Chase (not injury-related) and Tee Higgins (hamstring) may not be available for the Week 1 opener versus the New England Patriots. If that's the case, the rookie could see more snaps than anticipated, assuming he's cleared to suit up. Granted, Burton will need to compete primarily with Trenton Irwin and Andrei Iosivas for the attention of Joe Burrow. Still, fantasy managers in 12-team leagues and up should keep Burton on the back burner in the event Chase and Higgins are both ruled out.

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Pittsburgh Steelers wide receiver Van Jefferson will face off against his former team, the Atlanta Falcons, in Week 1. Jefferson has flashed potential since entering the league in 2020 and begins his fifth professional season with an opportunity to become the WR2 in Pittsburgh. The 28-year-old impressed throughout camp and drew praise from the Steelers' coaching staff all summer. Unfortunately, he'll have his work cut out for him on Sunday against a Falcons defense that limited wideouts to the sixth-fewest fantasy points in the NFL last season. Jefferson's role in new play-caller Arthur Smith's offense is worth monitoring but he is best left on fantasy waiver wires for now.

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Miami Dolphins wide receiver Malik Washington (quad) has been officially ruled out for the team's home opener against the Jacksonville Jaguars. Washington was able to practice Wednesday and Thursday in a limited fashion, but a downgrade for Friday's practice will sideline him for Week 1. Unfortunately, the explosive rookie's debut will be delayed -- and, as of now, the timetable for his return is unclear. It's ill-fated news for the sixth-round pick as there is a window for him to make his case as the Dolphins' WR3 with Odell Beckham Jr. and River Cracraft to miss the season's first four games while on the PUP. Braxton Berrios will work as Miami's third wideout for the majority of the matchup, with Grant DuBose mixing in to give him a break. Receivers Anthony Schwartz and Tahj Washington are also on IR, leaving the Fins with just four healthy wide receivers.

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Cincinnati Bengals running back Chase Brown ran for 179 yards off 44 carries in his rookie season, adding 14 grabs for 156 yards and a touchdown. With Joe Mixon now in Houston, many anticipate the 24-year-old will be more involved than ever. Granted, Cincinnati signed Zack Moss to a two-year deal this offseason, so he'll also be on the field. However, there's a good chance both players will split carries equally out of the backfield throughout the 2024-25 campaign. With that in mind, the Bengals will begin the year with a Week 1 matchup versus the New England Patriots. But Ja'Marr Chase (not injury-related) and Tee Higgins (hamstring) may not suit up. If that's the case, Brown deserves flex consideration in every fantasy format, considering he may see more carries and targets from Joe Burrow.

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Dallas Cowboys tight end John Stephens Jr. (hamstring) has been officially ruled out of Sunday's game against the Cleveland Browns. Stephens Jr. picked up the injury this week at practice, appearing on the Cowboys' first injury report of the season. It's a tough development for the second-year TE, as he missed his entire rookie season with a torn ACL. However, this should not affect Dallas' game plan as he is the fourth of four tight ends held by Dallas. The 24-year-old is the only player on the Cowboys' active roster not available for the team's road opener this Sunday. The former Horned Frog was also the only player not participating in Wednesday's practice. A week of rest should do the young tight end some good as he'll look to return to health in anticipation of Dallas' home opener against the New Orleans Saints in Week 2.

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Cleveland Browns kicker Dustin Hopkins will kick off his 2024 season with a home matchup against the Dallas Cowboys in Week 1. The Cowboys were tough on fantasy kickers last year, allowing just the 29th-most fantasy points per game to the position. Hopkins was a reliable kicker for the Browns in 2023, hitting 33 of his 36 field-goal tries, including all eight of his tries from 50+ yards. It remains to be seen how efficient the Cleveland offense will be this season, which coupled with the tough matchup, leaves Hopkins outside of the top-12 fantasy kicker options this weekend.

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Cleveland Browns wide receiver Jerry Jeudy will take on the Dallas Cowboys at home in Week 1. Jeudy, who is making his Cleveland debut, dealt with a knee injury during training camp but he appears to be fully healthy heading into the season opener. Jeudy reportedly showed nice chemistry with Deshaun Watson during the preseason, although it remains to be seen whether that transfers over to the regular season. For now, Jeudy appears to be the team's No. 2 or No. 3 option in the passing game behind Amari Cooper and possibly David Njoku. For now, he sets up as a low-end flex, and fantasy managers should be in wait-and-see mode until it is more clear how Jeudy fits into the Cleveland offense.

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Cincinnati Bengals running back Zack Moss signed a two-year deal with the team this offseason. He's coming off the best year of his career, running for 794 yards and five touchdowns off 183 attempts, adding 27 catches for 192 yards and 2 touchdowns in 14 games with the Colts. With Joe Mixon now in Houston, the door is open for someone to take over the No. 1 spot in the backfield. Although some predict Moss will see the majority of the touches over Chase Brown, at least early in the year, his fantasy outlook isn't as clear while the likelihood of a timeshare exists. But Ja'Marr Chase (not injury-related) and Tee Higgins (hamstring) aren't a lock to suit up in Week 1. As a result, Moss could see more touches than usual. He may also see more attention on the receiving end from Joe Burrow (wrist), who could start the 2024-25 campaign without his two primary receiving options. With that said, Moss should be a starting fantasy option in nearly all formats on Sunday, especially if Higgins or Chase are out. The same would be true for Brown, who would be in line for more snaps against the Patriots.

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Cleveland Browns tight end David Njoku will look to build upon a breakout season last year when he takes on the Dallas Cowboys at home in Week 1. The Cowboys represent a tough matchup for tight ends as they allowed just the 25th-most fantasy points per game to the position in 2023. That being said, Njoku emerged as a top option in the passing attack last year and should continue to be one of the top targets for Deshaun Watson this season. Fantasy managers can comfortably fire Njoku up as a top-10 tight end for the season opener this weekend.

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Arizona Cardinals tight end Tip Reiman (ankle) is officially listed as questionable for Sunday's game against the Buffalo Bills. Reiman practiced all week in a limited fashion, but it appears his ankle hasn't progressed enough for him to be cleared for the Cardinals' opening road tilt. With the third-string tight end sidelined, it's fair to expect Elijah Higgins to garner some more snaps, with fourth-string option Travis Vokolek to mix in for some as well, possibly. The rookie third-round pick doesn't project to have a significant role in Arizona's offense right out of the gate. Even if the Illinois product is healthy, Trey McBride is the clear leader of this unit. Fantasy managers can avoid Reiman in the early season, and he's nothing more than a deep dynasty league stash for the time being.

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Cleveland Browns running back Jerome Ford will open the season as the team's starter after Nick Chubb (knee) was placed on the PUP list. Ford draws a tough Week 1 matchup as he will take on the Dallas Cowboys on the road to kick off the 2024 season. The Cowboys were stout against the run in 2023, allowing just the 22nd-most fantasy points per game to running backs. Ford was very average as a rusher last season but he did show skill in the passing attack, hauling in five touchdown grabs on 44 catches. He should be busy in the passing game against an explosive Dallas offense this week, making him a solid flex option for fantasy gamers.

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Cleveland Browns wide receiver Amari Cooper will head on the road to take on his old team in a Week 1 showdown against the Dallas Cowboys. Dallas represents a tough matchup for Cooper as they allowed just the 28th-most fantasy points per game to wide receivers in 2023. The Cowboys' secondary should be just as formidable in 2024 as they will get Trevon Diggs back after losing him to a season-ending injury early last season. Cooper has shown the ability to post week-winning performances during his career but the matchup leaves him as more of a low-end WR2 in fantasy for the season opener on Sunday.

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Cincinnati Bengals quarterback Joe Burrow (wrist) logged another full practice on Friday, meaning he should be good to go in Week 1 versus the Patriots. Unfortunately, the signal-caller could be without his top weapons, with Ja'Marr Chase (not injury-related) and Tee Higgins (hamstring) potentially not suiting up for the opener. Without question, Burrow is a capable fantasy quarterback. However, his outlook isn't as promising if Chase and Higgins aren't on the field. But it's a new era in New England, with Bill Belichick no longer at the helm in favor of Jerod Mayo. With the coaching change, there could be bumps in the road for the Patriots defense. Regardless, Burrow is too talented to keep on the bench on Sunday. Fantasy managers should consider him a viable starting option in all formats imaginable.

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Cleveland Browns quarterback Deshaun Watson will kick off his 2024 season with a tough road matchup against the Dallas Cowboys. Watson did not see any game action in the preseason after his 2023 campaign was cut short by a shoulder injury suffered during Week 12 against the Baltimore Ravens, so there may be a bit of rust to knock off for the signal-caller. The Cowboys represent a tough matchup for Watson as they allowed just the 26th-most fantasy points per game to the quarterback position last season. Watson's tenure with the Browns has been marked by inconsistency, although he will play with the best group of pass catchers he has had since joining the team two years ago. Treat Watson as a low-end QB2 with some upside for the season opener.

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Pittsburgh Steelers wide receiver George Pickens finished as the fantasy WR26 last season and will be looking to establish himself as a true No. 1 option in 2024. His first opportunity to do so will come against the Atlanta Falcons in Week 1. Atlanta was stout against opposing wideouts in 2023, allowing the sixth-fewest fantasy points to the position. To make matters worse, it is currently unclear who will throw Pickens the ball on Sunday with quarterback Russell Wilson (calf) officially listed as questionable. The good news for fantasy managers is that Wilson or Justin Fields under center should be a clear upgrade for Pickens compared to the Steelers' quarterbacks of the past two years. Pittsburgh demonstrated its confidence in Pickens as a WR1 when it traded away Diontae Johnson in March, setting up the 23-year-old for a breakout campaign. There is risk in relying on Pickens this week, but he offers a high ceiling as a low-end WR2 or flex play despite a difficult matchup.

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Pittsburgh Steelers running back Najee Harris is set to begin his fourth professional campaign against the Atlanta Falcons on Sunday. Although the Steelers conducted one of the least productive offenses in the NFL last season, Harris still managed to rush for over 1,000 yards and eight touchdowns. The 26-year-old will have an opportunity to best those numbers in 2024 behind what should be an improved offensive line and with new offensive coordinator Arthur Smith calling plays. Atlanta poses a difficult challenge for Harris as the Falcons surrendered the fifth-fewest fantasy points to the running back position in 2023. With Jaylen Warren returning from a hamstring injury, however, Harris should be expected to lead Pittsburgh's backfield and thus projects as a viable RB2 or flex option in most fantasy lineups.

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Miami Dolphins star cornerback Jalen Ramsey (hamstring) is officially listed as questionable for Week 1 of the regular season this Sunday at Hard Rock Stadium versus the visiting Jacksonville Jaguars. The good news, though, is that Ramsey was able to put in a limited practice on Friday after sitting out both Wednesday and Thursday. The 29-year-old All-Pro corner signed a three-year, $72.3 million contract extension on Friday with Miami, making him the highest-paid corner in the NFL. Ramsey considers himself a game-time decision for Sunday's contest. If he's not active, it will be good news for Jaguars top wideout Christian Kirk. It would also force backup cornerback Ethan Bonner into a starting role in Miami's secondary. Ramsey is a better real-life defensive back than an IDP one.

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New England Patriots tight end Hunter Henry (foot) has been removed from Friday's final injury report and will be good to go for the Week 1 regular-season opener this Sunday versus the Cincinnati Bengals. Henry was a full participant in the first official practice of the year on Wednesday, so there was never really any doubt whether he'd suit up and play this weekend after dealing with a foot injury during training camp. Fantasy managers can't really get too excited about any of the offensive skill players in New England's offense this year in what is expected to be one of the most lackluster units, but the 29-year-old Henry could be a valuable safety blanket for both quarterbacks Jacoby Brissett and Drake Maye as they play catchup on the scoreboard more often than not. Heading into Week 1, fantasy managers should treat Henry as a TE2 sleeper against Cincy.

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When asked if there's any doubt in his mind that he will play in the Week 1 regular-season opener on Monday against the visiting New York Jets, San Francisco 49ers running back Christian McCaffrey (Achilles, calf) simply said, "No." When asked if he's expecting a normal workload, McCaffrey said, "I hope so." For the second straight day on Friday, CMC was listed as limited on the team's injury report. ESPN's Nick Wagoner writes that McCaffrey seemed to be moving at full speed with no issues on Friday. The 28-year-old All-Pro RB missed most of training camp and all of the preseason due to an Achilles/calf injury, but he's been working on side fields since mid-August and should be active on Monday night. However, the top overall pick in most fantasy drafts will have more of a bust factor in the season opener against a nasty defense if he's limited at all. Fantasy managers would be wise to handcuff him with Jordan Mason.

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