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San Francisco 49ers rookie wide receiver Jordan Watkins (ankle) has been removed from the injury report and will make his NFL debut in Week 2 against the New Orleans Saints this Sunday. Watkins, a fourth-rounder in April, was held out of the Week 1 win over the Seattle Seahawks after suffering a high-ankle sprain all the way back on Aug. 9, but not only will he be active this weekend, but he could be thrown into the fire right away. Tight end George Kittle (hamstring) is on Injured Reserve, while receiver Jauan Jennings (shoulder) is questionable for Sunday. Backup quarterback Mac Jones is starting in place of the injured Brock Purdy (toe), but if Jennings is out, Watkins will be battling with Kendrick Bourne, Marquez Valdes-Scantling, and Skyy Moore for WR2 duties. Watkins will be too dicey to start in fantasy, but he's certainly one to watch in deeper leagues now that he's past his ankle injury.

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Parker Gabriel of The Denver Post writes that Denver Broncos running back Tyler Badie could have an elevated role in the passing attack out of the backfield in a Week 2 matchup against the Indianapolis Colts because of Colts defensive coordinator Lou Anarumo's tendency to bring a lot of "pressure looks." Although Badie didn't have a carry in the Week 1 win over the Tennessee Titans, he was targeted six times through the air and caught two of them for 16 yards. The 25-year-old is not a realistic starting option in Week 2 fantasy lineups, even in PPR leagues, but his presence on the field is bad news for fantasy managers expecting rookie RJ Harvey to see a bigger share of the backfield work in Week 2. Badie's six targets ranked third on the team last weekend in Denver.

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Jacksonville Jaguars tight end Brenton Strange has a real opportunity to break out in 2025 in his third year in the league under new head coach Liam Coen, even though his Week 1 production wasn't eye-opening. Strange caught all four passes thrown his way for 59 total yards in a game in which the Jags offense took their foot off the gas pedal after halftime and a lengthy weather delay. The 24-year-old led the team in yardage in the season opener and finished second in receptions, behind only rookie first-round receiver Travis Hunter. Against a Cincinnati Bengals defense in Week 2 that was very friendly to opposing offenses a year ago, Strange could have a bigger day this Sunday. In the one-point win over the Cleveland Browns in Week 1, the Bengals' defense allowed 10 catches and 100 yards combined to rookie TE Harold Fannin Jr. and David Njoku.

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While Dallas Cowboys owner Jerry Jones didn't exactly say that rookie running back Jaydon Blue would be active in Week 2 this Sunday against the division-rival New York Giants, he did say that Blue is "going to make a difference when it's all said and done." Blue really impressed the coaching staff in training camp this summer, but an ankle injury caused him to miss time late in camp and resulted in the 21-year-old being a healthy inactive in last Thursday's season-opening loss to the Philadelphia Eagles. The expectation is that Blue will be a healthy scratch again this weekend against the Giants, but he could contribute sooner than later, especially if Miles Sanders looks bad again, like he did in Week 1. For now, expect Javonte Williams and Sanders to handle backfield duties in Dallas for another week. Fantasy managers must remain patient with Blue.

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While nobody is mistaking New York Jets quarterback Justin Fields for two-time MVP Lamar Jackson, the former first-rounder does have a similar dual-threat skill set at the position and could give the Buffalo Bills defense more issues after they couldn't stop Jackson and the Ravens offense at all in Week 1. Fields and the Jets offense looked much better in their loss to the Pittsburgh Steelers, with Fields accounting for three touchdowns (one passing, two rushing). The 26-year-old went 16-for-22 passing for 218 yards while rushing 12 times for 48 yards. Buffalo's defense also gave up three total touchdowns to Jackson while allowing 40 total points, so on that logic alone, Fields and the Jets offense could keep it going in Week 2 at home. Field's rushing upside alone should give him a high floor with QB1 potential every week in fantasy.

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New Orleans Saints tight end Juwan Johnson likely was off the fantasy radar in most leagues to begin the year, but he's become a popular waiver-wire target heading into Week 2 after his eight-catch, 76-yard performance (on 11 targets) in the Week 1 loss to the Arizona Cardinals. Johnson surprisingly led the Saints in catches and yards on the day in the debut of head coach Kellen Moore, with second-year quarterback Spencer Rattler under center. The Saints aren't suddenly an offense to watch, but it was notable that Rattler dropped back to pass 46 times -- New Orleans will probably be playing from behind a lot in 2025. Johnson has never gone over 548 receiving yards in five NFL seasons, but he did score seven times in 2022 and could be a trusted weapon for Rattler all year long. He'll face a tougher Niners defense this week, but if you lost George Kittle (hamstring) or Dallas Goedert (knee) already, Johnson could be a serviceable short-term solution.

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Tennessee Titans rookie running back Kalel Mullings (ankle) is listed as doubtful to face the Los Angeles Rams in Week 2 in the team's home opener. Mullings did not practice on Wednesday or Thursday before getting in a limited practice on Friday. The 22-year-old was the team's RB3 in the season-opening loss to the Denver Broncos last Sunday but was quickly injured on a punt return in the first quarter. Although he isn't on the radar in the majority of single-year fantasy leagues early in the year, Mullings' injury is notable for a Titans RB room that is already missing Tyjae Spears (ankle) for at least the first four games. Tony Pollard and Julius Chestnut will once again operate as the top two backs against the Rams. The Titans' only other option at the position is Jordan Mims, and he's currently on the practice squad.

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Grant Paulsen of 106.7 The Fan says that he heard that Washington Commanders quarterback Jayden Daniels (knee) got an MRI exam done on his knee on Friday after getting banged up in the Thursday night loss to the Green Bay Packers. Daniels never left the 27-18 loss, but he was limping "pretty good" at the end of the game, and Paulsen suggests it's something worth keeping an eye on. The good news is that the Commanders have a long layoff until their Week 3 clash against the Las Vegas Raiders on Sunday, Sept. 21. The 24-year-old second-year QB threw for 200 yards and two touchdowns on 24-for-42 passing on Thursday night, adding seven rushes for 17 yards. Washington's offense looked sluggish on a short week against a strong Packers D. If his knee isn't an issue, Daniels will have a prime chance to bounce back in Week 3 as a high-end QB1 in fantasy.

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Tampa Bay Buccaneers kicker Chase McLaughlin didn't have great results during the season opener against the Atlanta Falcons last week. He went 1-for-2 on field goal attempts and 2-for-3 on extra point attempts in the win. McLaughlin missed a 44-yard field goal in the third quarter and snagged an extra point attempt in the fourth quarter. Not an ideal outing for McLaughlin, but he deserves the benefit of the doubt after missing only two field goals all of last season. He figures to remain busy given the Bucs high-powered offense. Fantasy managers should continue to ride with him as a streaming option for the Week 2 matchup against the Houston Texans on Monday night.

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Tampa Bay Buccaneers wide receiver Emeka Egbuka got his NFL career started off with a bang last week. The rookie wideout hauled in four of his six targets for 67 yards and two touchdowns in the win over the Atlanta Falcons. He delivered a beautiful 30-yard score in the second quarter. Egbuka found the end zone again with a 25-yard grab as the game-winning score. It's tough to have a much better debut than that right there. He figures to continue having a significant role in the offense with Chris Godwin (ankle) and Jalen McMillan (neck) both out. In PPR formats, Egbuka should be viewed as a low-end WR2 for the upcoming Week 2 matchup against the Houston Texans.

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Tampa Bay Buccaneers tight end Cade Otton was unable to get anything going during the season opener last week. Otton failed to bring in any of his three targets in the win. It's worth noting that Otton was dealing with a groin injury heading into this game. Possibly, Otton's lack of contribution was due to his groin problems. He appears to be fine heading into the Week 2 matchup against the Houston Texans. It's worth noting that Otton has topped 35 yards in just one of his last seven outings, dating back to last season. It's probably best if Otton is left on the bench until he proves he can be a reliable contributor.

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Tampa Bay Buccaneers wide receiver Mike Evans didn't have a great season opener, but was still able to contribute in the win. Evans hauled in five of his eight targets for 51 yards in the victory over the Atlanta Falcons. The veteran wideout finished with the team-high in receptions and targets. However, Evans saw his fantasy value take a dip with Emeka Egubka and Bucky Irving catching the three touchdowns. Fantasy managers shouldn't be worried as Evans is one of the most consistent wideouts in the league. He should get the benefit of the doubt and remain on the WR1 radar for the upcoming matchup against the Houston Texans.

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Tampa Bay Buccaneers running back Bucky Irving didn't have an ideal season opener last week. Irving had trouble finding any room to run as he rushed for 37 yards on 14 attempts in the win over the Atlanta Falcons. He was able to salvage his fantasy value by hauling in all four of his targets for eight yards and a touchdown. Despite the struggles, Irving will remain the lead back in Tampa Bay with Rachaad White only seeing two rushing attempts in the opener. The Bucs are committed to Irving and he'll continue seeing a heavy workload. Irving should remain in the RB1 conversation for the upcoming Monday night matchup against the Houston Texans.

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Tampa Bay Buccaneers wide receiver Chris Godwin (ankle) was listed as a non-participant in Friday's practice after he was limited in Thursday's session. Godwin practiced with the team on Thursday for the first time this year after suffering an ugly ankle dislocation in Week 7 in 2024. While the 29-year-old is making progress, Friday's DNP is a reminder that he's a long shot to make his return in Week 2 on Monday Night Football against the Houston Texans. Godwin still has a lot of boxes to check with his ankle, but if he keeps making progress, he may be able to return this month. Fantasy managers should be stashing Godwin everywhere, but don't get your hopes up if he doesn't come back in Week 3 against the New York Jets, either. Rookie first-round wideout Emeka Egbuka really impressed in Week 1 and should continue to be a must-start in fantasy with Godwin sidelined.

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Tampa Bay Buccaneers running back Rachaad White was barely seen on the field during the season opener against the Atlanta Falcons last week. White rushed the ball twice for 14 yards and hauled in his lone target for two yards in the win. Bucky Irving is the clear-cut RB1 in Tampa Bay right now. White figures to remain involved in the passing game, but he didn't see a ton of action in the opener. This early in the season it's tough to gauge how much White will be used in the offense. That being said, White is looking like a bench option for the upcoming Week 2 matchup against the Houston Texans. White is worth stashing in certain formats because he's the primary backup to Irving, but it doesn't look like he's going to see much of the field right now.

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Tampa Bay Buccaneers quarterback Baker Mayfield wasn't excellent in the season opener, but he got the job done. Mayfield completed 17-of-32 passing attempts for 176 yards with three touchdowns and zero interceptions in the win over the Atlanta Falcons. The passing yardage was low for Mayfield, but he is missing two of his wide receivers in Chris Godwin (ankle) and Jalen McMillan (neck) right now. The three scores gave fantasy managers a good game, so they don't have much to complain about. The Bucs should continue being a pass-heavy offense which should make Mayfield a viable weekly option. Mayfield should once again remain in the mid-range QB1 territory for the upcoming Monday night matchup against the Houston Texans in Week 2.

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Minnesota Vikings running back Aaron Jones Sr. is a high-end RB3/Flex candidate as his team takes on the Atlanta Falcons in Week 2. In its first game, Minnesota came up with a solid blueprint that the team is likely to try again, with the veteran earning the lion's share of the backfield receiving work and fellow running back Jordan Mason taking many of the tough running downs. From a fantasy perspective, Jones will get enough rushing work to pair nicely with his receiving ability to consider starting him, especially in PPR formats. The Vikings have shown they trust Jones in big passing situations, and with receiver Jordan Addison (suspension) still out, he's likely to earn at least a few key targets.

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The San Francisco 49ers have officially ruled out quarterback Brock Purdy (toe) for Week 2 action against the New Orleans Saints, according to NBC Sports' Matt Maiocco. Purdy is dealing with turf toe despite playing the entirety of the Week 1 win over the Seattle Seahawks last weekend. Not only will the 25-year-old miss this Sunday's game, but reports this week have suggested that he could be out multiple weeks. It's more bad news for an extremely battered Niners team early in 2025. Tight end George Kittle (hamstring) is also out this weekend and will miss at least four games after being placed on Injured Reserve. Former New England Patriots QB Mac Jones will run San Fran's offense against the Saints. Expect plenty of short and intermediate throws while they lean heavily on running back Christian McCaffrey. At best, Jones is a desperation QB2 in superflex fantasy leagues.

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Minnesota Vikings quarterback J.J. McCarthy is a high-end Superflex option as his team plays host to the Atlanta Falcons in Week 2. Following a brutal first half in the season-opener at Chicago, the Michigan product came alive in the second half, accounting for three fourth-quarter touchdowns and his first NFL win. Now playing behind a home crowd and facing a friendlier matchup from a fantasy perspective, McCarthy has a reasonable opportunity to improve on a lackluster Week 1 from a completions and yards perspective. Attached to a strong supporting cast, McCarthy should give managers some value at the Superflex spot.

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San Francisco 49ers wide receiver Jauan Jennings (shoulder) is officially listed as questionable to play in Week 2 on Sunday against the hosting New Orleans Saints, according to Matt Maiocco of NBC Sports. Jennnings injured his shoulder in the Week 1 win over the Seattle Seahawks and did not return before missing the first two practices of the week on Wednesday and Thursday. However, the 28-year-old was able to get in a limited practice on Friday, which gives him a chance to suit up for the extremely banged-up Niners. If Jennings plays, both he and Ricky Pearsall should be peppered with targets with tight end George Kittle (hamstring) out. However, quarterback Brock Purdy (toe) is also out, which makes Jennings a pretty volatile and unpredictable fantasy option this weekend if he ends up playing. The former seventh-rounder had only two grabs for 16 yards in the opener before getting hurt.

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