Kansas City Chiefs quarterback Patrick Mahomes will face the Buffalo Bills in Week 11. The 29-year-old found himself on the injury report with an ankle/hip injury but practiced fully all week and has been removed from the injury report ahead of the contest. Mahomes was trending up until he faced the tough Denver Broncos defense in Week 10. Mahomes passed for 266 yards and one touchdown in last week's contest at Arrowhead. The Chiefs quarterback will now take on a Buffalo Bills defense ranked fifth in fantasy points allowed to opposing quarterbacks this season. Despite these teams being two high-powered passing offenses in the past, this game has the makings of a defensive showdown. Kansas City and Buffalo have strong defenses and an affinity for running the ball to dominate time of possession. This week, Mahomes is ranked QB13 in our RotoBaller rankings, placing him outside QB1 territory. Fantasy managers may be disappointed with Mahomes if this contest turns into a defensive affair.

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Green Bay Packers running back Josh Jacobs (quad) is off the injury report after putting in a full practice session and is good to go for Sunday's Week 11 divisional clash against the Chicago Bears. With two limited practice sessions on Wednesday and Thursday, Jacobs may still be a bit banged up even after the Packers' bye in Week 10. Jacobs has been solid for fantasy managers, but hasn't delivered much in the way of spike weeks with just two top-ten finishes among fantasy running backs in nine weeks. Against the Chicago Bears, Jacobs remains a workhorse running back who will see the bulk of carries and provide a solid floor double-digit fantasy point floor as a high-end RB2.

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Atlanta Falcons tight end Kyle Pitts is within the top 10 in fantasy scoring at the position through 10 weeks of the season despite some inconsistent play, including a zero-catch performance in Week 4 and a one-catch performance in Week 9. The 24-year-old rebounded last week with four catches for 55 yards and this week gets a Denver defense that is middle of the pack in allowing production to TEs, although Travis Kelce torched them for 64 yards and a touchdown on eight catches last week. Pitts has a solid aDOT of 8.16 which has allowed him to average 14.3 yards per reception, so he doesn't need many catches to maintain relevance in PPR leagues. However, with his volatility still a concern, the former first-round draft pick projects as a back-end TE1 in Week 11.

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New Orleans Saints wide receiver Cedrick Wilson Jr. (shoulder) was limited in practice all week and is considered questionable to suit up on Sunday to face the visiting Cleveland Browns in Week 11. Wilson hasn't really been on the fantasy radar at all this year. The 28-year-old suffered a shoulder injury in the Week 9 loss to the Carolina Panthers and did not suit up in the Week 10 win over the division-rival Atlanta Falcons. Wilson could be a true game-time decision, but it shouldn't matter much to fantasy managers, even with top wideout Chris Olave (concussion) on Injured Reserve. The former sixth-round pick by the Dallas Cowboys in 2018 out of Boise State has only 11 receptions (14 targets) for 122 yards and one score in eight games in 2024. If he's active, Wilson is likely to start in three-wide sets with Marquez Valdes-Scantling and rookie Mason Tipton.

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The Detroit Lions have officially ruled out tight end Sam LaPorta (shoulder) for the Week 11 contest this Sunday against the visiting Jacksonville Jaguars. LaPorta suffered an AC joint sprain in his shoulder in the Week 10 win over the Houston Texans last Sunday night and will now miss at least one game. The 23-year-old second-year TE was listed as day-to-day earlier this week, so there is some hope he'll only miss one game and return to face the Indianapolis Colts in Week 12. With LaPorta out this weekend, expect both Brock Wright and Shane Zylstra to see the field more in two-TE sets, with Wright being the better target as a TE2 streamer in deeper leagues and DFS. LaPorta's absence should also mean more targets for receivers Amon-Ra St. Brown, Tim Patrick and Kalif Raymond.

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New Orleans Saints running back Jamaal Williams (groin) was unable to practice all week and has been ruled out for Week 11 against the Cleveland Browns on Sunday. This will be Williams' third straight game missed due to a groin injury. Lead back Alvin Kamara had already been a workhorse back for the Saints before Williams' injury, but it ensures the 29-year-old will continue to see the lion's share of touches for the Saints, although Taysom Hill could be a bit more involved against Cleveland. Jordan Mims will operate as Kamara's primary backup with Kendre Miller (hamstring) still on Injured Reserve. At best, Williams is a handcuff option for fantasy managers in deep leagues that have Kamara rostered. Williams only has 32 carries for 124 yards and a touchdown in eight games played in 2024 in his second year with the Saints.

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Kansas City Chiefs wide receiver JuJu Smith-Schuster (hamstring) practiced in full on Thursday and Friday and has been cleared to play in Week 11 on Sunday against the Buffalo Bills. Smith-Schuster will return for the first time since getting injured on Oct. 20 but won't be as interesting for fantasy managers now that DeAndre Hopkins is the team's top wideout. In his last game, the 27-year-old went off for 130 receiving yards, prompting many fantasy managers to pick him up off the waiver wire given how depleted KC's receiving corps was at the time. He'll still have a role as a deep threat for quarterback Patrick Mahomes now that he's back, but at best, he'll be the No. 3 target behind Hopkins and stud tight end Travis Kelce. Smith-Schuster should be considered a boom/bust WR4/flex, at best, in his return against the Bills.

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Green Bay Packers running back MarShawn Lloyd (ankle, hamstring) is dealing with appendicitis and will not be active for the team's Week 11 divisional contest against the Chicago Bears on Sunday. "It is a shame, certainly. This all happened this morning. He felt some pain his abdomen this morning. Not sure if he's had surgery," head coach Matt LaFleur said. Lloyd was designated to return from Injured Reserve at the start of the week and had a shot to make his return to the field this weekend, but that won't happen now. The 23-year-old has been very injury-prone since joining the Packers and has played in just one game in his first season in the NFL. He suffered a high-ankle sprain earlier this year and will now miss an eighth straight game. Lloyd has explosive rushing ability as a backup to Josh Jacobs and is worth a stash in deeper leagues, but it's now unclear if he'll be able to return in Week 12 against the 49ers.

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Cincinnati Bengals pass-rusher Trey Hendrickson (neck, personal) will not travel with the rest of the team to Los Angeles for personal reasons but is expected to fly on his own and play on Sunday night against the Chargers in Week 11. Hendrickson is officially listed as questionable on the final injury report, but fantasy managers in IDP leagues should leave the 29-year-old in their starting lineups this weekend. He has been dealing with a neck injury off and on this year, but it hasn't slowed him down, as he heads into Week 11 action as the NFL's sack leader with 11 through 10 weeks. Hendrickson was limited in Wednesday's practice before not practicing on Thursday and Friday. He has not missed a game all year and should be active for Sunday Night Football.

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As expected, Kansas City Chiefs running back Isiah Pacheco (leg) has officially been ruled out for the Week 11 game against the Buffalo Bills on Sunday. Pacheco had his 21-day practice window opened this week in order to return from Injured Reserve, but the 25-year-old isn't expected to return to action until later this month as he continues to recover from a fractured fibula that he suffered way back in Week 2. Fantasy managers must continue to stash him in an IR spot for the time being and hope he returns to his pre-injury form in time for the fantasy playoffs. Meanwhile, Kareem Hunt will continue to be a must-start for fantasy managers as KC's primary back, with Samaje Perine and rookie Carson Steele spelling him. Pacheco was limited in his return to the practice field this week.

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Atlanta Falcons wide receiver Drake London has been a consistent fantasy producer through 10 weeks, catching at least six passes in seven of those games and finding the end zone six times, putting him well within the top 10 in fantasy scoring at the position. However, it is going to be tough to replicate those numbers in Week 11 against a strong Denver pass defense that has allowed the fourth-fewest fantasy points to wideouts thus far. The silver lining is that they have been a bit more beatable in recent weeks, allowing five TDs to receivers over the last four weeks compared to just one in the season's first six weeks. With a 25.5% target share and 32.9% of the team's air yards, his role is secure in this offense and figures to be a back-end WR1 in Week 11.

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Kansas City Chiefs head coach Andy Reid said that kicker Harrison Butker (knee) injured his left knee in practice this week and underwent surgery on Friday morning. Reid did not have an official timeline for Butker's return yet, but the club placed him on Injured Reserve, meaning he'll have to miss at least the next four games. The earliest Butker will be able to return will be on Dec. 15 against the Cleveland Browns in Week 15. The 29-year-old veteran had a repair of his meniscus. If fantasy managers have the room on IR, they could consider stashing Butker, as he could be back for the first week of the fantasy playoffs in most leagues. In the meantime, the Chiefs will roll with rookie undrafted kicker Spencer Shrader, who they signed off the New York Jets' practice squad this week. We'd recommend avoiding Shrader as a fantasy streamer this Sunday against Buffalo.

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Minnesota Vikings running back Aaron Jones (ribs) has been removed from the injury report ahead of the Week 11 matchup against the Tennessee Titans. Jones has been limited in practice this week due to a ribs issue. Despite that, Jones has been cleared to play, so he should be feeling better. Jones has seen a fairly heavy workload with 14 carries or more in each of the last four games. He'll get a tough matchup against the Titans defense, but remains a RB2 for this weekend.

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Atlanta Falcons wide receiver Darnell Mooney (Achilles) has been removed from the injury report ahead of the Week 11 matchup against the Denver Broncos. There was some concern over Mooney's status after he was a limited participant in practice on Thursday. Although, Mooney doesn't appear to be dealing with anything serious as he has already been removed from the injury report. Mooney has been a solid fantasy option this season. He has five receptions for over 80 yards in each of the last two games. He does draw a tough matchup against the Broncos secondary, but fantasy managers should still be able to trust Mooney to produce as a WR3.

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Minnesota Vikings quarterback Sam Darnold (hand) has been removed from the injury report ahead of the Week 11 matchup against the Tennessee Titans. Darnold has been limited in practice this week, but appears ready to play this weekend. He's coming off a rough performance against the Jacksonville Jaguars where he threw three interceptions in the win. The hope is that Darnold will rebound this weekend now that the hand issue is hopefully behind him. Fantasy managers should be able to count on Darnold to play better in Week 11.

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Cincinnati Bengals wide receiver Tee Higgins (quad) has been removed from the injury report ahead of the Week 11 matchup against the Los Angeles Chargers. Higgins appears to be ready to play for the first time since Week 7. He missed three games due to a quad issue, but the fact he was removed from the injury report means that he'll play this weekend. Before going down, Higgins was a significant part of the offense with seven of more targets in four of his five games this season. It's worth noting that the Chargers defense has been tough to pass against this season. That being said, Higgins falls more into the low-end WR2 conversation for Week 11.

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Miami Dolphins defensive back Kendall Fuller (concussion) is likely to miss some time after suffering his second concussion during last week's win over the Los Angeles Rams. Head coach Mike McDaniel confirmed that Fuller is currently considered week-to-week. They haven't placed him on the injured reserve, which is a good sign. Fuller won't suit up this weekend against the Las Vegas Raiders. That means, Cam Smith is likely to serve as the opposite corner to Jalen Ramsey for at least one game. The loss of Fuller hurts the Dolphins secondary, but they should still have streaming appeal against the struggling Raiders offense.

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New York Jets wide receiver Davante Adams (illness, wrist) is expected to play in Week 11 on Sunday versus the Indianapolis Colts, according to interim head coach Jeff Ulbrich. In addition to an illness that caused him to miss practice on Wednesday and Thursday, Adams is dealing with a minor wrist issue. He was able to get back on the practice field on Friday, though, and should be active on Sunday as the Jets look to turn things around. Although fantasy managers may have been expecting more from the All-Pro wideout after being traded to the Jets, Adams should remain a must-start in fantasy lineups as long as he's active. The 31-year-old veteran has 20 catches on 39 targets for 206 yards and a touchdown in his four games with the Jets and gets a nice matchup against a Colts defense that has allowed the 10th-most half-PPR points per game to receivers this year.

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New York Jets linebacker C.J. Mosley (neck) and left tackle Tyron Smith (neck) have both been ruled out for the Week 11 game against the Indianapolis Colts on Sunday. The Jets will re-evaluate Mosley after the Week 12 bye, and the team is still gathering more information on Smith's injury, according to interim head coach Jeff Ulbrich. Meanwhile, safety Chuck Clark (ankle) is being activated from Injured Reserve. Mosley is missing his fourth straight game but hopefully will have a shot to return when the team returns from their bye to take on the Seattle Seahawks in Week 13. With the 32-year-old out again, it will mean more opportunities for both linebackers Quincy Williams and Jamien Sherwood. The 33-year-old Smith suffered a neck injury in the Week 10 loss to the Arizona Cardinals and may not be ready coming out of next week's bye.

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Baltimore Ravens head coach John Harbaugh said he's optimistic that All-Pro safety Kyle Hamilton (ankle) will be able to suit up in Week 11 to face the division-rival Pittsburgh Steelers on Sunday. Hamilton was injured in last Thursday night's one-point win over the division-rival Cincinnati Bengals but was able to practice on Wednesday and Thursday. It's excellent news for IDP fantasy managers and Baltimore's secondary with a tough matchup against an improving Steelers offense under quarterback Russell Wilson. Hamilton sprained his right ankle last Thursday but is trending in the right direction to play this weekend. If he's active, he should be in starting lineups in the defensive back spot in IDP formats. The 23-year-old is currently the No. 4 fantasy DB with 50 total tackles, two sacks, seven pass breakups, a forced fumble and a fumble recovery in 10 games played.

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