San Francisco 49ers quarterback Brock Purdy faces the division-rival Seahawks in Seattle for a Week 6 matchup on Thursday night. In a surprising one-point home loss to the Arizona Cardinals last week, Purdy left something to be desired with a 19-for-35, 244-yard effort, including a touchdown, two interceptions, and 33 yards rushing. Seattle is 11th-best in the NFL at limiting fantasy quarterbacks in Yahoo default scoring. However, the Seahawks are dealing with significant injuries on defense, which boosts Purdy's outlook. Starting defenders CB Riq Woolen, DT Byron Murphy II, and LB Uchenna Nwosu have all been ruled out, plus two linebackers and a safety have been tagged questionable. Running back Christian McCaffrey (Achilles/calf) remains on Injured Reserve, but Purdy is otherwise equipped with a fully healthy offense. He'll look to beat projections for just the second time this year as a mid/low QB1.

From RotoBaller

Tampa Bay Buccaneers running back Rachaad White (foot) was listed as limited in the team's first practice of the week. The third-year back was efficient in the Buccaneers' 36-30 loss to the Falcons last Thursday night, averaging 7.2 yards per carry over his ten rush attempts. However, he appeared to be bent awkwardly while being taken to the ground by an Atlanta defender. White returned to the contest after leaving the field but did not look to be 100%. It's an encouraging sign that he could practice in at least a limited fashion, but fantasy managers will want to monitor his status over the coming days. Rookie running back Bucky Irving will handle most of the running back touches if White can't play. The 25-year-old has improved his efficiency on the ground over the last two weeks and still leads this backfield in snaps. However, the former fourth-round pick has closed the snap-share gap since Week 3. Atlanta gets a formidable opponent in Week 6 when they take on the New Orleans Saints on the road.

From RotoBaller

Tampa Bay Buccaneers wide receiver Trey Palmer (concussion) was listed as a non-participant for the team's first practice of the week. The 23-year-old has been on the shelf since Tampa Bay's Week 4 victory over the Philadelphia Eagles when he picked up a concussion. Palmer will have two more opportunities to upgrade his practice participation ahead of a Week 6 road tilt against the New Orleans Saints. If he can't, he'll be at risk of missing his second-straight contest. Wideouts Jalen McMillan (hamstring) and Kameron Johnson (ankle) were each able to get in limited sessions on Wednesday. If Palmer can't play on Sunday, that duo would be in line to pick up more snaps behind Mike Evans, Chris Godwin, and Sterling Shepherd. Shepherd has the third-most WR snaps for the team over the last two weeks.

From RotoBaller

Free-agent QB C.J. Beathard (Jaguars) and free-agent QB Nate Sudfeld (Lions) worked out for the Tennessee Titans Wednesday, Oct. 9.

From TheHuddle

Las Vegas Raiders WR Davante Adams (hamstring) did not participate in practice Wednesday, Oct. 9.

Fantasy Spin: Adams is not expected to play this week, but fantasy players can keep an eye on the situation to see if anything changes. Brock Bowers may be the only Raiders pass catcher that is a must-start option in fantasy leagues.

From TheHuddle

Cleveland Browns S Grant Delpit (concussion), DE Myles Garrett (Achilles), S Ronnie Hickman (ankle), OT James Hudson (shoulder), C Ethan Pocic (knee) and CB Denzel Ward (hamstring) did not participate in practice Wednesday, Oct. 9. OT Jack Conklin (hamstring), LB Mohamoud Diabate (hip), LB Jordan Hicks (elbow, triceps), RB Nyheim Hines (knee), DT Maurice Hurst (ankle), RB Pierre Strong (hamstring), OT Jedrick Wills (knee) and OG Zak Zinter (knee) were limited during practice. DE Ogbo Okoronkwo (illness) fully participated in practice.

From TheHuddle

Cleveland Browns RB D'onta Foreman (ankle) did not participate in practice Wednesday, Oct. 9.

Fantasy Spin: Foreman has been sharing playing time with Jerome Ford, so fantasy players should keep an eye on the situation to see if Foreman will be available. He could be a possible flex option in leagues if he plays.

From TheHuddle

Cleveland Browns WR Amari Cooper (non-injury) did not participate in practice Wednesday, Oct. 9.

Fantasy Spin: Cooper has been targeted at least eight times in every game so far this season and should continue to see a good amount of targets. The Browns passing game has not had a lot of success, but he can still be at least a flex option in leagues.

From TheHuddle

Cleveland Browns RB Nick Chubb (knee) was limited during practice Wednesday, Oct. 9.

Fantasy Spin: It is not known when Chubb will be added to the 53-man roster, so fantasy players should continue to monitor the situation. He may not receive a normal workload when he returns but likely will take over the starting job at some point. He should be a starting fantasy option in the near future.

From TheHuddle

Los Angeles Chargers LB Joey Bosa (hip), PK Cameron Dicker (illness), CB Kristian Fulton (knee), S Derwin James (non-injury), CB Deane Leonard (hamstring) and CB Ja'Sir Taylor (leg) did not participate in practice Wednesday, Oct. 9. OT Joe Alt (knee), LB Junior Colson (hamstring), LB Daiyan Henley (shoulder), TE Hayden Hurst (Achilles), LB Khalil Mack (non-injury), LB Denzel Perryman (shoulder), CB Asante Samuel Jr. (shoulder) and OT Rashawn Slater (pectoral) were limited during practice.

From TheHuddle

Jacksonville Jaguars running back Travis Etienne Jr. (shoulder) is on the injury report again in Week 6 after putting in a limited practice on Wednesday. Etienne was also limited in practice all of last week before being active in the Week 5 win over the division-rival Indianapolis Colts, seeing nine touches for 60 yards. He aggravated his shoulder injury and barely played in the second half, watching backfield mate Tank Bigsby once again take over and provide 128 scrimmage yards and two touchdowns. The 25-year-old Etienne should be fine to play in Week 6 in London against the Chicago Bears, but it's a bad matchup, and he could continue to cede touches to the more productive and explosive Bigsby. As things currently stand, Etienne's fantasy arrow is pointing down. If he's active in London, he'll be a shaky RB2 for fantasy managers at risk of losing more playing time to Bigsby.

From RotoBaller

Jacksonville Jaguars wide receiver Gabe Davis (knee) was once again limited in the first practice of the week on Wednesday. Davis led all Jaguars receivers in offensive snaps in the Week 5 win over the division-rival Indianapolis Colts, but it led to only three receptions on four targets for 38 yards. In his first year in Jacksonville, Davis has been more of an afterthought for the 1-4 Jags, catching 12 of 25 targets for 159 yards and no touchdowns. The 25-year-old's chances of breaking out this Sunday in London against a stout Chicago Bears defense don't seem great, especially if tight end Evan Engram (hamstring) returns for the first time since the season opener. Davis should be just fine to suit up in Week 6 this weekend, but fantasy managers should have better options to use in their flex spot. Davis isn't even among the top-50 receivers in half-PPR fantasy scoring through five weeks.

From RotoBaller

Denver Broncos WR Josh Reynolds (hand) did not participate in practice Wednesday, Oct. 9.

Fantasy Spin: Reynolds has received only six targets in the last three games and only had nine receiving yards in Week 5. He probably will see a few targets this week but can be avoided in fantasy leagues.

From TheHuddle

After being suspended for the Week 5 win over the Los Angeles Rams, Green Bay Packers wide receiver Romeo Doubs returned to practice on Wednesday and wasn't limited in any fashion. Doubs decided to skip a few practices last week because he was unhappy with his role in the offense, so the Packers suspended him for a game due to conduct detrimental to the team. The 24-year-old reportedly is back on the same page with the team and should be active for Week 6 against the visiting Arizona Cardinals. It's possible Green Bay could look to involve him more this Sunday in a good matchup, although receiver Christian Watson (ankle) could also make his return. The Packers have a lot of mouths to feed in the receiving corps among Doubs, Watson, Jayden Reed and Dontayvion Wicks. Fantasy managers will be rolling the dice if they use Doubs as a WR4/flex in Week 6 against the Cardinals.

From RotoBaller

Jacksonville Jaguars tight end Evan Engram (hamstring) was limited in the first practice of the week on Wednesday. The Jaguars are optimistic that Engram can return to action in Week 6 against the Chicago Bears in London this Sunday after not playing since the season-opening loss to the Miami Dolphins. Engram injured his hamstring during pre-game warmups before Week 2 and hasn't played since. The 30-year-old two-time Pro Bowler had a career-best 963 receiving yards in 2023 in his second year in Jacksonville, but so far in 2024 he's been a fantasy bust due to his hamstring injury. Engram caught just one pass for five yards in Week 1. If he ends up returning to the field this Sunday in London, he'll be a low-end TE1 in fantasy, at best. Brenton Strange has filled in nicely for the Jags in Engram's absence and has found the end zone twice.

From RotoBaller

Indianapolis Colts wide receiver Michael Pittman Jr. (back) is expected to miss multiple weeks. The Colts have also suggested that Pittman may be placed on injured reserve. Pittman was a non-participant in practice on Wednesday and is listed as doubtful heading into this weekend. This is unfortunate news for fantasy managers as Pittman had just started to come alive. He had at least 113 receiving yards or a touchdown in his last two games. That may be attributed to the presence of quarterback Joe Flacco in the lineup rather than a struggling Anthony Richardson. However, it could be some time before fantasy managers find out if Pittman is able to build on that momentum. Pittman has recorded 22 receptions for 238 yards and a touchdown in 2024. For now, fantasy managers will have to stick him in their IR spot and hope for the best.

Dynasty | The Texans have placed wide receiver Nico Collins on injured reserve. Dynasty Analysis: Collins has gone from an afterthought, to a serviceable receiver, to a possible lineup staple, to a WR1, to perhaps the best receiver in fantasy leagues over the past three years. This is a major buzzkill as he has been flat-out dominant. Savvy owners who aren't competing right now could make a "buy low" play for his services to a team desperate to win, but you're not likely to get him. Unfortunately, he's going to be out for at least four weeks and that should open up targets for Tank Dell, Stefon Diggs, Dalton Schultz and others.

Tampa Bay Buccaneers C Graham Barton (hamstring), S Christian Izien (elbow, groin) and WR Trey Palmer (concussion) did not participate in practice Wednesday, Oct. 9. WR Kameron Johnson (ankle) S Jordan Whitehead (groin) and S Antoine Winfield Jr. (foot) were limited during practice. DE Earnest Brown (ribs), DE William Gholston (knee), OT Luke Goedeke (concussion) and DT Calijah Kancey (calf) fully participated in practice.

From TheHuddle

New Orleans Saints OG Cesar Ruiz (knee), DE Payton Turner (knee), QB Derek Carr (oblique), OG Lucas Patrick (chest), S Will Harris (hamstring) and LB Pete Werner (hamstring) did not participate in practice Wednesday, Oct. 9. LB Willie Gay (hand) was limited during practice, while RB Kendre Miller (hamstring) fully participated in practice.

From TheHuddle

New Orleans saints TE Taysom Hill (rib) did not participate in practice Wednesday, Oct. 9.

Fantasy Spin: Hill is still recovering from fractured ribs, so he probably will not be available this week unless he takes part in one of the two practices left during the week. Fantasy players should look for other options and avoid Hill until he takes part in a few practices.

From TheHuddle