Seattle Seahawks running back Kenneth Walker III (oblique) is officially inactive for Sunday's game against the New England Patriots. He had been listed as doubtful entering the weekend, so this latest update does not come as a surprise. The star running back will watch from the sidelines as Zach Charbonnet operates as the Seahawks' No. 1 running back. Charbonnet has some high-end RB3/FLEX appeal against a Patriots defense that did allow a rushing touchdown despite playing a strong game against the Cincinnati Bengals last week.

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Indianapolis Colts wide receiver Josh Downs (ankle), who is dealing with a high-ankle sprain and was considered 50-50 to play in Week 2 against the Green Bay Packers, has been ruled out on Sunday as caution prevails. Downs suffered the high-ankle sprain in training camp in August and also was inactive for the season-opening loss to the division-rival Houston Texans. The good news, though, is that he was able to practice in full on Friday, so perhaps he'll be ready to make his season debut in Week 3 against the Chicago Bears. With Downs out again, it makes both Alec Pierce, who went over 100 yards and a touchdown in Week 1, and rookie Adonai Mitchell a little more attractive as flex plays in deeper fantasy leagues at Lambeau Field. But when Downs does make his way back, he could eventually settle into the WR2 role in Indy behind Michael Pittman Jr.

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Green Bay Packers wide receiver Jayden Reed (calf, shin) is officially active for Week 2 against the Indianapolis Colts. He had been listed as questionable after practicing in a limited capacity on Friday. Still, as the weekend progressed, Reed was trending toward playing. Indeed, he'll suit up on Sunday. Unfortunately for Reed and his fantasy managers, the Packers have ruled out quarterback Jordan Love (knee), which means Malik Willis will get the start at quarterback. It's unclear whether Willis is capable of supporting steady fantasy production from his playmakers, which means Reed drops to the WR3/FLEX tier in most leagues this week. He can still get involved in the rushing attack and break off big plays, but it's hard to envision him replicating his 138 receiving yards from the season opener.

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There is a possibility that Pittsburgh Steelers QB Justin Fields could remain as the team's starting quarterback even after QB Russell Wilson (calf) has fully recovered from his aggravated calf injury, according to multiple sources.

Fantasy Spin: Head coach Mike Tomlin could stick with the hot hand if the Steelers keep winning and if Fields continues to execute the team's game plan while limiting turnovers. For now, Fields should only be used as a starting lineup option in two-quarterback fantasy leagues.

From TheHuddle

The Washington Commanders have declared LB Jamin Davis, WR Jamison Crowder, QB Sam Hartman, S Darrick Forrest Jr., S Dominique Hampton, CB Emmanuel Forbes and OT Chris Paul inactive for Week 2.

From TheHuddle

The Philadelphia Eagles intend to elevate wide receiver Parris Campbell from their practice squad to their active roster for Week 2, according to NFL Network's Mike Garafolo. Campbell will give the Eagles additional reinforcement at wide receiver in case A.J. Brown (hamstring) or Johnny Wilson (hamstring) can't suit up. Campbell is less than two years removed from a solid 2022 campaign with the Colts in which he caught 63 passes for 623 yards and three touchdowns. He did take a step backward with the Giants last season, but at the very least, he's proven that he can be a productive receiver before. He'll contribute on offense if activated this week, but likely not enough to justify adding him in fantasy football leagues.

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Dallas Cowboys tight end Jake Ferguson (knee) is officially inactive for Week 2 against the New Orleans Saints. He had been listed as doubtful. The third-year tight end tested his injury in warmups, but it was quickly evident that he wouldn't be healthy enough to suit up on Sunday. Luke Schoonmaker will start at tight end in Ferguson's absence. He'll likely command some volume, but not enough to justify starting him in most fantasy football leagues this week. CeeDee Lamb is the only Dallas pass-catcher to start with confidence in Week 2, although Brandin Cooks is an intriguing FLEX play in deeper formats.

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New Orleans Saints CB Marshon Lattimore (hamstring) is expected to be inactive for the Week 2 game, according to sources.

From TheHuddle

Green Bay Packers running back Emanuel Wilson was the primary backup behind Josh Jacobs during the season opener. The 25-year-old did well as he rushed for 46 yards on four yards with two receptions as well. It was a decent outing given his fairly small workload, which could be reduced even more in Week 2. Fellow back MarShawn Lloyd (hamstring) is expected to suit up against the Indianapolis Colts this weekend. He figures to be in the mix as well behind Jacobs, which means there probably won't be much fantasy value from Wilson or Lloyd. Both backs are going to play second fiddle to Jacobs who is the workhorse back in Green Bay. The other two backs could be worth stashing in deep leagues, but they aren't worth starting right now.

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Philadelphia Eagles wide receiver A.J. Brown (hamstring) is currently listed as questionable heading into the Week 2 matchup against the Atlanta Falcons. This news came suddenly after Brown's hamstring tightened up on him during Friday's practice. As a result, Brown was placed on the injury report and considered questionable due to the fact it was so late in the week. However, it sounds like Brown's status is a legitimate question heading into this matchup. It wouldn't be shocking to see the Eagles take this down to the wire, which is frustrating for fantasy managers. His absence would mean an increased workload for DeVonta Smith, Dallas Goedert, and Saquon Barkley. Possibly, Jahan Dotson gets into the mix, but remains a risky fantasy option even if Brown sits out.

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Green Bay Packers quarterback Jordan Love (knee) has already been ruled out for the Week 2 matchup against the Indianapolis Colts. This comes as no surprise after Love suffered an MCL sprain during the final moments of the Week 1 loss to the Philadelphia Eagles. The Packers haven't placed Love on the injured reserve as they only expect him to miss a few weeks. The young signal-caller is reportedly targeting a return in Week 5. It looks like the Packers will still need to get through a few games before Love is ready to play again. That being said, Malik Willis will suit up for Week 2 and figures to remain the starter until Love returns. If he struggles, the Packers could turn to Sean Clifford or bring in a quarterback from outside the organization. However, it seems unlikely that the Packers would bring in another legitimate QB with Love only missing a few weeks. For now, Willis will start under center and he can be avoided in most fantasy formats.

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Green Bay Packers running back MarShawn Lloyd (hamstring) is currently listed as questionable ahead of the Week 2 matchup against the Indianapolis Colts. Despite that, Lloyd is expected to suit up and make his NFL debut. This same hamstring issue held him out during the season opener, but it appears Lloyd is feeling better now. He figures to serve as the primary backup to Josh Jacobs. His workload is unknown, but he should at least be involved in the rushing attack. The rookie back isn't worth starting while Jacobs is healthy, but he should be rostered in all dynasty leagues and stashed in deep leagues.

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Miami Dolphins quarterback Tua Tagovailoa (concussion) has been subject to a bunch of rumors following his injury during Thursday's game against the Buffalo Bills. The young signal-caller suffered what appears to be his fourth concussion over the last five years. As a result, Tagovailoa will meet with neurologists this week to discuss his current condition and his future in the league. However, Tagovailoa has already said he has no plans to retire. He's already seeing concussion specialists and will continue to do so going forward. There still remains no timetable for Tagovailoa's return, but there should be more updates in the coming weeks. Until then, Skylar Thompson figures to start under center for Week 3 and possibly longer.

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The Dallas Cowboys elevated TE Princeton Fant and LB Nick Vigil from their practice squad to the active roster Saturday, Sept. 14, for Week 2's game against the New Orleans Saints.

From TheHuddle

Los Angeles Rams wide receiver Jordan Whittington is someone who could possibly see more action with the team shorthanded at wideout. Stud wideout Puka Nacua (knee) was placed on the injured reserve which means he'll miss at least the next four games. His absence could open up additional playing time for Whittington. However, it's worth noting that Whittington only played two snaps during the season opener. The assumption is that Cooper Kupp, Demarcus Robinson, and Tyler Johnson figure to be the starting trio for this offense. That doesn't mean Whittington can't be involved as well, but he probably won't see enough targets to warrant rostering in most formats outside of dynasty leagues.

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San Francisco 49ers running back Christian McCaffrey (calf, Achilles) was placed on the injured reserve on Saturday. This news comes after McCaffrey was sidelined for the season opener due to Achilles tendinitis and a calf strain. He'll miss at least the next four games after being placed on the injured reserve, but he could be out longer than that. Ian Rapoport believes it could take up to six weeks for McCaffrey to heal from his Achilles tendinitis. Possibly, McCaffrey is able to play through the issue after his stint on the injured reserve, but fantasy managers should prepare for him to miss up to six weeks. In his absence, Jordan Mason figures to be the lead back and should be rostered in just about every fantasy format after his showing in Week 1.

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Carolina Panthers running back Miles Sanders was the leading rusher for this offense during the Week 1 loss to the New Orleans Saints. Being the leading rusher sounds nice, but Sanders only finished with 22 yards on five carries. He served as the second string back to Chuba Hubbard, but neither back got anything going last week. To be fair, it was a blowout and the Panthers needed to abandon the passing game in the second half of the contest. Regardless, neither player has a good outlook heading into the Week 2 matchup against the Las Vegas Chargers. It looks like both backs are going to split the workload, which is bad news for values as a whole. Sanders could be a deep or dynasty stash, but he isn't worth rostering in most fantasy formats.

From RotoBaller

New Orleans Saints CB Marshon Lattimore (hamstring, hip) has been pushing to play in Week 2's game versus the Dallas Cowboys and will participate in pregame workouts to determine if he will play. He had been listed as questionable on the injury report after being unable to participate in any of the team's three practice sessions during the week.

From TheHuddle

Miami Dolphins quarterback Tua Tagovailoa (concussion) is reportedly scheduled to meet with neurologists early next week. This news comes after Tagovailoa was diagnosed with a concussion following an early exit from Thursday's game against the Buffalo Bills. The meeting with the neurologists should give Tagovailoa better input on his situation and whether or not it's safe for him to play football again. The young quarterback has already been diagnosed with four concussions over the last five years. Dolphins' head coach Mike McDaniel said he wants Tagovailoa to focus on his health, which basically means there's no timetable for his return. Skylar Thompson figures to be the starting quarterback unless the team makes a trade or signs a free agent. The Dolphins are likely going to wait until they get more information on Tagovailoa's status before they make any significant moves.

From RotoBaller

Cincinnati Bengals wide receiver Tee Higgins (hamstring) is expected to be inactive for Week 2 against the Kansas City Chiefs, according to ESPN's Adam Schefter. Higgins had been listed as doubtful and was trending toward missing his second consecutive game. His absence isn't official yet and won't be confirmed until 90 minutes before kickoff, but fantasy managers should still start making lineup adjustments and finding players to replace Higgins. Internally, Andrei Iosivas and Trenton Irwin are candidates for more volume, but neither of them should be deployed in typical 12-team leagues.

From RotoBaller