New England Patriots safety Kyle Dugger (ankle) is officially active for Week 6 against the Houston Texans. He had been listed as questionable after logging a limited practice on Friday. The 28-year-old remains productive despite the Patriots' 1-4 record, registering 18 tackles, one sack, and one forced fumble. His presence will be key as the Patriots look to slow down C.J. Stroud and the Texans in Drake Maye's first career start.

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Cleveland Browns cornerback Denzel Ward (hamstring) is officially active for Week 6 against the Philadelphia Eagles. He had been listed as questionable after logging a limited practice on Friday. The 27-year-old defender has contributed eight tackles and zero turnovers through five games this season. He'll be tasked with slowing down a Philadelphia passing attack featuring A.J. Brown and DeVonta Smith on Sunday.

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New England Patriots wide receivers Kendrick Bourne (knee) and K.J. Osborn (shoulder) are active for Week 6 against the Houston Texans. Both players were listed as questionable after being limited in practice all week long. Bourne made his season debut last weekend, turning his lone target into a six-yard catch. He played just 27 percent of the offensive snaps, but that could have been a product of him playing in his first game of the year. He's likely headed for extra snaps in Week 6. Meanwhile, Osborn has seen his workload scaled back with the emergence of rookie Ja'Lynn Polk. He caught one pass on five targets when last active in Week 4. Even with Drake Maye taking over as the Patriots' quarterback, neither Bourne nor Osborn can be trusted in fantasy football given their respective roles behind Polk and Demario Douglas.

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New England Patriots wide receiver Javon Baker (coach's decision) and Tyquan Thornton (coach's decision) are inactive for Week 6 against the Houston Texans. Both players are healthy scratches. Baker has repeatedly been inactive, failing to log an offensive snap since Week 2. He's still searching for his first NFL target and will have to wait at least one more week. Thornton, meanwhile, has been the subject of trade rumors lately but lacks significant fantasy appeal; he hasn't registered a reception since catching two passes back in the season opener. Both players can be dropped in all redraft and most dynasty leagues.

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Arizona Cardinals PK Matt Prater (knee) is not active for Week 6's game against the Green Bay Packers. PK Chad Ryland, who was elevated from the practice squad Saturday, Oct. 12, will serve as the team's kicker.

Fantasy Spin: Prater had been listed as questionable on the injury report after being a limited participant in all three of the team's practice sessions during the week but will miss his second consecutive game. Fantasy owners should be able to find more reliable placekicking options for their lineups elsewhere.

From TheHuddle

Houston Texans RB Joe Mixon (ankle) is officially active for the Week 6 game.

Fantasy Spin: Mixon likely will be the starting running back for the Texans, but it is not known if he will be able to handle his normal workload. He should be a No. 2 back or flex option in fantasy leagues.

From TheHuddle

Tampa Bay Buccaneers running back Rachaad White (foot) is officially inactive on Sunday against the division-rival New Orleans Saints in Week 6. White missed the final two practices of the week on Thursday and Friday and was deemed doubtful to play this weekend, so fantasy managers should have already moved him to their benches. In addition to being hurt and inactive this week, White had already been losing most of his fantasy steam while being out-produced by rookie backfield mate Bucky Irving early on in 2024. If White is able to return for next Monday night's clash against the Baltimore Ravens, there's a good chance he'll play in more of a backup role to Irving. With White on the sidelines on Sunday, Irving is basically a must-start RB2 for fantasy managers with upside for more. Through five games, White is averaging a mediocre 3.7 yards per carry and has no rushing TDs on 51 rushing attempts.

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Indianapolis Colts wide receiver Michael Pittman Jr. (back) is officially active for Week 6 against the Tennessee Titans. He went from being an injured reserve candidate to being listed as questionable to being active for Sunday's game. Pittman evidently made remarkable progress this week and figures to be a key contributor for Indianapolis ahead of its divisional clash on Sunday. He also gets a boost from Joe Flacco, the Colts' talented veteran passer who was named the starter after Anthony Richardson (oblique) was scratched at the last minute. Pittman ranks as a fringe top-24 wide receiver for fantasy purposes.

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Tampa Bay Buccaneers rookie wide receiver Jalen McMillan (hamstring), who was listed as questionable, is active for the Week 6 divisional game on Sunday against the New Orleans Saints. With Trey Palmer (concussion) missing another game, McMillan should operate as the team's WR3 behind Mike Evans and Chris Godwin. The 22-year-old youngster is returning after missing each of the team's last two games due to a hamstring ailment. In his first three NFL games, McMillan operated as the No. 3 and caught just three of his six targets for 59 yards and one touchdown. The Saints defense has allowed the 19th-most half-PPR fantasy points to wideouts through the first five weeks of the season, so they aren't exactly the greatest matchup for pass-catchers, especially at home in the Caesars Superdome. McMillan is stash-worthy in deeper fantasy leagues, but we wouldn't recommend him for starting lineups this weekend.

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Indianapolis Colts wide receiver Josh Downs (toe) is active for Sunday's divisional battle against the Tennessee Titans. He missed two consecutive practices earlier in the week but then progressed to a full participant on Friday. His improved status allowed him to enter this weekend listed as questionable, and he continued to trend in the right direction ahead of gameday. Now, Downs has been confirmed as active and is expected to operate as the Colts' No. 2 wide receiver alongside Michael Pittman Jr. The 23-year-old is averaging an impressive 8.5 catches, 75.5 receiving yards, and 0.5 touchdowns through two games with Joe Flacco, and he should continue to make an impact with Flacco named the starter over the injured Anthony Richardson (oblique). Downs is a high-end fantasy WR3 with impressive upside this weekend.

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Jacksonville Jaguars running back Travis Etienne Jr. (hamstring) is questionable to return against the Chicago Bears in Week 6. It's unclear exactly when Etienne picked up the injury, but he hasn't registered an opportunity since dropping a pass early in the second quarter. Between injuries and poor play, Etienne has been an enormous disappointment in fantasy football lately, averaging just 60 scrimmage yards and zero touchdowns between Weeks 4 and 5. Now, if he doesn't return on Sunday, he'll finish Week 6 with three rushes for a loss of one yard on the ground, plus zero catches on one target. Tank Bigsby has suddenly become more dependable than Etienne in fantasy football, and that may hold true even if the latter gets a clean bill of health heading into next Sunday's clash with the Patriots in London.

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Green Bay Packers wide receiver Christian Watson (ankle) is officially active in Week 6 on Sunday against the visiting Arizona Cardinals at Lambeau Field. Watson suffered a left high-ankle sprain in Week 4 and missed the Week 5 win over the Los Angeles Rams, but he'll surprisingly end up missing just one game with an injury that was expected to sideline him multiple contests. It's good news for the Packers, but fantasy managers may want to be wary of relying on him in starting lineups, especially with Romeo Doubs also returning from a one-game suspension. Watson does have a touchdown this year, but he's also caught only five passes on eight targets for 80 yards in the four games he's played. The crowded nature of Green Bay's receiving corps makes all of their pass-catchers boom/bust WR4/flex plays outside of Jayden Reed.

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Baltimore Ravens cornerback Marlon Humphrey (ankle) and offensive tackle Ronnie Stanley (toe) are active for Sunday's game against the Washington Commanders. Both players were listed as questionable but were trending in the right direction this weekend. Humphrey's presence is key as the Ravens look to slow down Washington's offense. The 28-year-old has 22 tackles and two interceptions through five games this year. Meanwhile, Stanley gives a massive boost to Baltimore's offense, especially Lamar Jackson and Derrick Henry. He has played all but two offensive snaps this season, remaining a key playmaker in the trenches.

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The New Orleans Saints have declared OG Lucas Patrick, QB Derek Carr, TE Taysom Hill, RB Kendre Miller, OG Cesar Ruiz, DT Khristian Boyd and LB Pete Werner inactive for Week 6.

From TheHuddle

The Houston Texans have declared SS Jimmie Ward, OG Nick Broeker, CB Kamari Lassiter, DE Rashad Weaver and WR Robert Woods inactive for Week 6.

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The Indianapolis Colts have declared RB Jonathan Taylor, QB Anthony Richardson, WR Anthony Gould, LB Genard Avery and OG Danny Pinter inactive for Week 6.

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The Arizona Cardinals have declared CB Darren Hall, TE Travis Vokolek, PK Matt Prater, DE Victor Dimukeje and DE Xavier Thomas inactive for Week 6.

From TheHuddle

The Cleveland Browns have declared QB Dorian Thompson-Robinson, S Ronnie Hickman, C Ethan Pocic, LB Jordan Hicks, S Grant Delpit, DL Quinton Jefferson and WR Jamari Thrash inactive for Week 6.

From TheHuddle

Indianapolis Colts QB Joe Flacco will be the starting quarterback for the Colts in Week 6, according to sources.

Fantasy Spin: The Colts want to give Anthony Richardson another week to rest, so Flacco will be under center again. He has played well in relief over the last two games but should only be a starting option in two-quarterback leagues.

From TheHuddle

Indianapolis Colts quarterback Anthony Richardson (oblique) is inactive for Sunday's game against the Tennessee Titans. He had been listed as questionable and was actually expected to play this week, but at the last minute, the Colts have made him inactive and will start Joe Flacco instead. It's worth noting that Richardson will be the Colts' emergency third quarterback on Sunday, so he could still enter the game if both Flacco and Sam Ehlinger become too injured to play. Nevertheless, the second-year quarterback should be moved to the bench in all fantasy leagues.

From RotoBaller