Indianapolis Colts rookie running back DJ Giddens saw a sharp decline in his usage during Week 2. After logging 25% of the snaps in the opener, his role was reduced to just 7% as Jonathan Taylor handled nearly all of the backfield work. The shift in snap share makes it clear that as long as Taylor is healthy, Giddens will struggle to carve out meaningful standalone value for fantasy managers. Still, his size and power make him a strong handcuff option, as he would likely step into a heavy workload should Taylor miss time at any point this season. For now, Giddens should be viewed more as a depth stash in deeper formats rather than a reliable contributor. His immediate value is limited, but his long-term upside remains tied directly to Taylor's availability.

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Buffalo Bills wide receiver Joshua Palmer has been a nice addition to the team's offense two weeks into the season. The former Los Angeles Charger ranks second among Bills WRs in catches (seven), targets (12), and yards (108), trailing only Keon Coleman in those categories. Palmer led the way with 47 receiving yards on two grabs in a win over the New York Jets in Week 2, when the Bills elected for a run-first approach instead of airing it out. They figure to have more success throwing the ball on Thursday against the Miami Dolphins, who have surrendered 33 points per game while yielding the league's highest completion percentage (78.8) and its second-highest QB rating (126.1). That should help set Palmer up for a relatively successful evening, though he's certainly not a high-end fantasy option. RotoBaller has Palmer as the 62nd-ranked WR going into Week 3.

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The Buffalo Bills' Matt Prater has been among the NFL's most effective kickers through the first two weeks of the season. The 41-year-old journeyman, who signed with the Bills on Sept. 4 to replace the injured Tyler Bass (groin), has nailed all six of his field-goal attempts while going 5-for-5 on extra points. Prater ranks fifth among kickers in fantasy scoring two weeks into the season, and he should have plenty of opportunities to add to his total on Thursday against the Miami Dolphins. While the Dolphins have given up a whopping 66 points in two games, the Bills' high-powered offense has put 71 on the board. All signs are pointing to another busy night for Prater, which gives him plenty of upside heading into Week 3.

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Atlanta Falcons offensive coordinator Zac Robinson had good things to say about tight end Kyle Pitts Sr. through two weeks of the season. "Kyle is playing great. He's playing really good football. Really pleased with where Kyle is at. He's playing fast. He's getting extra work in with (tight ends coach Kevin) Koger," Robinson said. Pitts didn't have a stat line to write home about in the Week 2 win over the Minnesota Vikings on Sunday night, but he was heavily involved for the second straight week and caught four of his five targets for 37 yards in a game in which Atlanta really didn't need to throw the ball much. The 24-year-old has 11 catches for 96 yards through two games and should remain involved as one of the favorite targets for young quarterback Michael Penix Jr. Pitts will be on the TE1/2 borderline in Week 3, although the Falcons could once again lean on their running game in a friendly matchup against the division-rival Carolina Panthers.

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Buffalo Bills quarterback Josh Allen wasn't at his best in a win over the New York Jets in Week 2, but it could be a different story against the Miami Dolphins on Thursday. Allen has typically thrived against the AFC East rivals since entering the NFL in 2018. In 15 contests against Miami (including playoffs), Allen has gone 13-2 with 45 touchdowns (40 passing, five rushing), 10 interceptions, 273 passing yards per game, and a 107.6 QB rating. Worsening matters for the Dolphins, they have been ineffective against the pass so far this season. They've allowed the league's highest completion percentage (78.8) and its second-highest passer rating (126.1) despite facing non-elite signal-callers in Daniel Jones and Drake Maye. Miami has also given up the second-most fantasy points to QBs in 2025, making it hard to imagine that its defense will prevent Allen from rebounding in Week 3.

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After a stellar performance in a Week 2 win over the New York Jets, Buffalo Bills running back James Cook will take on one of the NFL's lowest-ranked run defenses on Thursday. Cook will match up against the division-rival Miami Dolphins, who have surrendered the eighth-most rushing yards per game (139.0) and the sixth-most fantasy points to running backs through two weeks. New England Patriots RB Rhamondre Stevenson had his way with the Dolphins last Sunday, as he piled up 142 total yards (54 rushing, 88 receiving) on 16 touches. Cook ranks fourth in the league in rushing yards (176) and has already found the end zone three times on the ground through two games. While Cook may have trouble matching last week's production (21 carries, 132 yards, two TDs), especially if he gets a lighter workload on a short week, he profiles as an RB1 going into Thursday.

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Buffalo Bills tight end Dalton Kincaid has gotten off to a respectable start through the first two games of the 2025 season. The former first-round pick has hauled in eight of 10 targets for 85 yards and a touchdown heading into a meeting with the Miami Dolphins on Thursday. For their part, the Dolphins have given up 12 catches, 146 yards, and the 10th-most fantasy points to tight ends in the early going. That sets up for Kincaid to have a fairly productive night, though a lack of scoring prowess may continue to limit his ceiling. Kincaid has totaled just five touchdowns 31 games into his career, while the Dolphins have not allowed a tight end to find the end zone this year.

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The Buffalo Bills relied more on the run than the pass in a Week 2 win over the New York Jets, which didn't do wide receiver Khalil Shakir any favors. Shakir had tallied six or more targets in 14 straight games entering last Sunday, but that streak ended against the Jets. After catching one of two targets for 12 yards, he'll look to bounce back against the Miami Dolphins on Thursday. Historically, Shakir has logged unspectacular numbers versus division-rival Miami, which has limited him to 20 catches, 260 yards, and no touchdowns in six career meetings. The 6-foot, 190-pounder caught 11 of 12 targets for 104 yards in two games against the Dolphins last year. That aligned with Shakir's season-long output during a 76-catch, 821-yard showing in 2024, and it's the type of respectable production fantasy managers should expect in Week 3.

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Buffalo Bills wide receiver Keon Coleman, the team's leading pass catcher so far this season, will enter a favorable matchup against the Miami Dolphins in Week 3. Miami, which may go without injured starting cornerback Storm Duck (ankle), hasn't had an answer for opposing passing games this year. The Dolphins are giving up 33 points per game and have allowed the NFL's highest completion percentage (78.8). That looks auspicious for Coleman, who caught all three targets for a modest 26 yards against No. 1 cornerback Sauce Gardner and the New York Jets' secondary last Sunday. The Bills beat the Jets handily while leaning on the run, whereas they took a pass-happy approach in a Week 1 victory over the Baltimore Ravens. Coleman looked like a budding star in the opener. While the second-year man remains unproven, he should be among the beneficiaries if Buffalo's Josh Allen-led aerial attack rebounds from an underwhelming Week 2 performance on Thursday.

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Cincinnati Bengals head coach Zac Taylor said he has "not shut the door" on a return this year for quarterback Joe Burrow (toe), according to Paul Dehner Jr. of The Athletic. However, Taylor doesn't have any timeline updates and doesn't know yet when Burrow will undergo surgery to fix torn ligaments in his toe. The 28-year-old is also dealing with turf toe after getting hurt in the Week 2 win over the Jacksonville Jaguars. While there is no official timeline for his return, Burrow is expected to miss at least three months, making it possible he could return at the tail end of the regular season. Fantasy managers with an IR spot available could stash Burrow, but just know that he may not end up helping you from here on out if you make a run in the playoffs. In the meantime, backup Jake Browning will run Cincy's offense. The Bengals offense will surely take a hit, but Browning can serve as a high-end QB2 in the right matchups.

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Washington Commanders wide receiver Noah Brown (groin) will not practice on Wednesday, although head coach Dan Quinn was more encouraged about Brown than he was on Monday, according to Zach Selby of Commanders.com. On Monday, Quinn said Brown was a long shot to play in Week 3 against the Las Vegas Raiders. The 29-year-old might still be fighting an uphill battle to play this weekend, but it's clear he's making progress after he injured his groin in Thursday night's loss to the Green Bay Packers. Even if Brown makes a lot of progress the next couple of days and is cleared to play against the Raiders on Sunday, he won't be a realistic starting option for fantasy lineups, with it looking like quarterback Jayden Daniels (knee) won't play in Week 3. Through the first two weeks of 2025, Brown has caught three of seven targets for just 36 yards.

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Kansas City Chiefs wide receivers Xavier Worthy (shoulder) and Jalen Royals (knee) will both practice on Wednesday, according to head coach Andy Reid. Worthy suffered a full tear of his right labrum in the season-opening loss to the Los Angeles Chargers when he collided with teammate Travis Kelce on the opening series of the game. He missed the Week 2 loss to the Philadelphia Eagles in the Super Bowl rematch, but the fact that he's back at practice gives him a chance to play this Sunday against the New York Giants on Sunday night as KC looks for its first 2025 win. It's good news that the 22-year-old is practicing, but his status could still be in doubt for Week 3, and with the game being on Sunday night this week, Worthy is shaping up as an extremely risky fantasy play. Royals missed the first two games of the season and can remain on the waiver wire in most redraft leagues while being buried on the WR depth chart.

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Jacksonville Jaguars wide receivers Brian Thomas Jr. and Travis Hunter had a tough time getting anything going in the Week 2 loss to the Cincinnati Bengals, but Parker Washington and Dyami Brown stepped up for quarterback Trevor Lawrence. Washington led the team with 76 receiving yards, but Brown had a team-best 12 targets and also tied Washington with five receptions. The 25-year-old finished with 57 yards and scored for the first time this season. Thomas and Hunter are going to be Lawrence's primary targets most weeks, but it's notable that Brown has topped 50 receiving yards in each of the first two weeks of the 2025 season. In new head coach Liam Coen's pass-happy offense, Brown could have a consistent role all year, and if anything were to happen to Thomas or Hunter, he could be a weekly flex option in fantasy. Put Brown on your watch list.

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Washington Commanders head coach Dan Quinn confirmed that quarterback Jayden Daniels (knee) will not practice on Wednesday, according to Tashan Reed of The Washington Post. Quinn said the team will have an update on Daniels after Friday's practice. Daniels sprained his knee in the Week 2 loss to the Green Bay Packers last Thursday night, and his availability for Week 3 against the Las Vegas Raiders is now up in the air. While we won't know for sure if the 24-year-old second-year signal-caller will play this weekend until Friday, it's looking like veteran backup Marcus Mariota will get the start. The Commanders had Mariota, and not Daniels, available to reporters on Wednesday. Fantasy managers need a backup plan in case Daniels is unable to practice and play this week. He may be a question mark for Week 4 against the Atlanta Falcons, too.

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The Houston Texans placed wide receiver Justin Watson (Achilles, calf) on Injured Reserve on Wednesday, according to the team's official website. Aaron Wilson of KPRC 2 Sports is reporting that Watson is dealing with an Achilles/calf injury, but it's not a tear, so he could potentially return later this season. The good news for Houston is that both receivers Christian Kirk (hamstring) and Braxton Berrios (hamstring) are expected to play in Week 3 against the division-rival Jacksonville Jaguars. For now, the 29-year-old Watson will have to miss at least the next four games. Watson wasn't on the fantasy radar anywhere to begin with, even with Kirk and Berrios missing the first two weeks of the season. Watson had three catches on four targets for 30 yards in the first two contests of 2025 before getting injured.

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San Francisco 49ers running back Isaac Guerendo entered the 2025 season as a prime handcuff for fantasy managers who were looking to score Christian McCaffrey at a discount early in drafts. However, Guerendo's fantasy value took a massive hit when the Niners acquired Brian Robinson Jr. from the Washington Commanders. B-Rob has been McCaffrey's backup through two weeks, relegating Guerendo to a distant RB3 role. In the Week 2 win over the New Orleans Saints, the 25-year-old didn't play a single snap on offense, with all 17 of his snaps coming on special teams. Guerendo averaged a healthy 5.0 yards per carry on 84 rushing attempts for 420 yards and four touchdowns in 16 games (three starts) as a rookie in 2024 when CMC was bothered by injuries, but currently, he's well off the fantasy radar in single-year leagues going into Week 3 against the division-rival Arizona Cardinals.

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Carolina Panthers rookie running back Trevor Etienne has played only four offensive snaps through the first two games of his first year in the NFL and is the clear RB2 in Carolina's backfield behind Chuba Hubbard and Rico Dowdle heading into a Week 3 divisional clash against the Atlanta Falcons. In the Week 2 loss to the Arizona Cardinals, the 21-year-old didn't have a carry and caught his only target for a two-yard gain while playing two snaps. Currently, the Georgia product is primarily being utilized as the team's kickoff-return specialist. He has returned five kicks for 101 yards through two weeks. Etienne is only worth rostering as RB depth in dynasty/keeper leagues right now, and he probably won't be worth a look on the waiver wire unless Hubbard or Dowdle miss time with an injury.

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New York Jets veteran backup quarterback Tyrod Taylor will make the start in Week 3 on Sunday against the hosting Tampa Bay Buccaneers after the Jets officially ruled out Justin Fields (concussion) on Wednesday, according to head coach Aaron Glenn. Taylor entered the Week 2 loss to the Buffalo Bills in the fourth quarter after Fields slammed his head on the turf and went 7-for-11 passing for 56 yards and a touchdown on two drives to end the 30-10 loss. The 36-year-old also had three carries for 21 yards. Taylor looked better than Fields did, albeit at the end of a blowout. Taylor can use his legs when needed, but he's made only five starts since the start of 2022, and none since 2023 with the New York Giants. Expect the Jets to lean even more on their ground game this weekend against a stout Tampa defensive line. In two-QB superflex leagues, Taylor will be a low-upside, low-end QB2 option for those already in trouble at the position.

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New York Jets quarterback Justin Fields (concussion) has been ruled out for Week 3 against the Tampa Bay Buccaneers, per NFL Network's Tom Pelissero . Fields was forced to leave New York's Week 2 contest early due to a concussion. Given how early in the week Fields has been ruled out, it's possible he could be facing a multi-week absence, but that's pure speculation at this stage. Veteran quarterback Tyrod Taylor will get the start against Tampa Bay in Fields' absence. Taylor completed seven of 11 pass attempts for 56 yards and a touchdown after taking over mid-game in Week 2. His last stretch of extended NFL action came in 2023 for the New York Giants, when he threw for 1,341 yards and five touchdowns and rushed for 197 yards on 38 attempts across 11 games (five starts). The 36-year-old Taylor still offers some dual-threat ability and could be a low-end injury replacement option in two-quarterback fantasy leagues.

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Washington Commanders quarterback Marcus Mariota is scheduled to meet with the media on Wednesday in place of Commanders quarterback Jayden Daniels (knee), per ESPN's John Keim. Keim notes that this does not mean that Daniels, who suffered a knee sprain in Week 2, will not be able to suit up in Week 3. Still, it could be an early indication that Washington is preparing for Mariota to make the start this Sunday against the Las Vegas Raiders. The 31-year-old Mariota played very well in limited action across three games for Washington in 2024. He completed 34 of 44 pass attempts for 364 yards and four touchdowns, adding 92 yards and a score as a rusher as well. If Mariota gets the start against Las Vegas, he could be a quality streamer/injury replacement option at the quarterback position, particularly in two-quarterback fantasy leagues.

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