San Francisco 49ers wide receiver Deebo Samuel Sr. faded into the background during a 24-23 home upset at the hands of the Arizona Cardinals on Sunday. Samuel Sr. saw three targets and caught just one for 11 yards. He also took three carries for nine yards rushing. The receiving total was the lowest a healthy Samuel Sr. has posted since Week 4 of his rookie year. In most games, San Francisco's passing attack is more evenly distributed, but Samuel Sr. saw receiver Brandon Aiyuk and tight end George Kittle each receive 12 targets. Samuel Sr. will likely be more involved when the 49ers face the Seahawks in Seattle on Thursday Night Football.

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San Francisco 49ers wide receiver Brandon Aiyuk finally broke out in a 24-23 home loss to the Arizona Cardinals on Sunday. Aiyuk was involved early and often in this one, posting eight receptions on 12 targets for 147 yards. He's still looking for his first touchdown, but early in 2023, Aiyuk went six games without a score before rattling off four straight games with a touchdown. Regardless, 18.7 half-PPR points will do for fantasy managers who were patient enough to keep him locked into their lineups as a WR2. The Nevada native will look for his first trip to the end zone when the 49ers face the Seahawks in Seattle on a short turnaround Thursday night.

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Cincinnati Bengals running back Chase Brown finished Sunday's overtime loss to the Ravens by compiling 46 yards off 12 carries. He added three catches for eight yards and a touchdown, finding the end zone off a four-yard pass from Joe Burrow in the fourth quarter. Zack Moss suffered an ankle injury in this one, so Brown was the featured backfield option. There's a chance Moss will miss the Week 6 matchup with the New York Giants. If that happens, Brown would be a lock for all fantasy lineups.

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Cincinnati Bengals running back Zack Moss finished the Week 5 loss to the Ravens by amassing 24 yards off nine carries. He added three receptions for 28 yards. Moss scored a touchdown in three of the Bengals' previous four contests. Unfortunately, he suffered an ankle injury during the contest. With that in mind, the 26-year-old is in danger of missing at least the Bengals Week 6 matchup with the New York Giants. If he's not out there, Chase Brown would become an automatic must-start.

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Cincinnati Bengals wide receiver Tee Higgins finished Sunday's loss to the Ravens by catching nine of his 14 targets for 83 yards. Even better, he found the end zone twice. After missing a few games to begin the year followed up by a few subpar showings in the Bengals' last two contests, the wideout looked fantastic in this one. While some fantasy managers lost Patience, they'll need to reconsider their stance for the Bengals Week 6 showdown with the New York Giants.

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San Francisco 49ers TE George Kittle ended up with eight receptions for 64 yards and a touchdown on 12 targets in Week 5 against the Arizona Cardinals.

Fantasy Spin: Kittle has managed at least four catches in four outings, and he has scored a touchdown in each of his past three games. He was forced to miss Week 3 due to injury, but when he is healthy, he is easily one of the best fantasy tight ends in the game.

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Cincinnati Bengals wide receiver Ja'Marr Chase looked good in Sunday's overtime loss to the Baltimore Ravens. The wideout caught 10 of his 12 targets for 193 yards. He also found the end zone twice, bringing his total to five touchdowns in the last three weeks. The former LSU Tiger has turned up the volume of late, so there's no reason to keep him out of fantasy lineups when the Bengals meet the Giants in Week 6.

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Denver Broncos WR Courtland Sutton caught two of his five targets for 32 yards in a 34-18 win over the Las Vegas Raiders in Week 5.

Fantasy Spin: Sutton was second on the team in targets and first among receivers, but the rest of his numbers continue lag behind his targets because of the Bo Nix's early struggles. Sutton is too inconsistent to be more than a flex option, but he could be a sleeper in the second half if Nix can make strides.

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San Francisco 49ers running back Jordan Mason had his least productive fantasy day of 2024 in a 24-23 home loss to the Arizona Cardinals on Sunday. He finished with a season-low 14 carries for 89 yards on the ground with no touchdowns and a game-changing fourth-quarter lost fumble. He caught his only target in the passing game for nine yards. On a day that featured record-setting heat at Levi's Stadium, Mason also ceded five carries to rookie Isaac Guerendo, which matches Guerendo's season high. With no firm timetable for the return of All-Pro Christian McCaffrey (Achilles), Mason will continue to operate as San Francisco's bell cow and a fantasy RB1 in a Week 6 Thursday night matchup at the Seattle Seahawks.

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Cincinnati Bengals quarterback Joe Burrow had a big game in Week 5. Unfortunately, his efforts weren't enough to secure a win over the Ravens. But the signal-caller did all he could, throwing for 392 yards and five touchdowns (one interception) off an efficient 30-for-39 passing. After a semi-slow start to the 2024-25 campaign, Burrow has played exceptionally well of late, tossing for over 300 yards in two of his previous three contests. He's also stayed healthy, which was a significant concern for fantasy managers. At any rate, Burrow is one of the most productive fantasy quarterbacks going, so he needs to be featured in all starting lineups when the Bengals meet the Giants in Week 6.

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San Francisco 49ers kicker Jake Moody (ankle) exited the team's 24-23 loss to the Arizona Cardinals after injuring his ankle on a tackle attempt and did not return. Per Adam Schefter, 49ers head coach Kyle Shanahan reported that Moody picked up a high ankle sprain after the game and is expected to miss multiple weeks. "So we'll get (a kicker) in as fast as possible and get the best guy we can," Shanahan said. "I'm sure it'll have to be for a few weeks or whatever." Despite the head coach's blais attitude, it's at least a moderate blow to the team as the 24-year-old has been one of the better kickers in the league thus far. Through five weeks, the former third-round pick had drilled 11-of-12 field goal tries (91.7%) and all ten of his extra-point attempts. Punter Mitch Wishnowsky made his only attempt -- a 26-yarder -- in Moody's stead, but it appears they'd prefer to look elsewhere for help while he's on the shelf with the ankle issue. The 49ers will suit up against the Seattle Seahawks in a road matchup this coming Thursday, so expect San Francisco to make a decision quickly regarding their kicking situation.

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San Francisco 49ers LB Fred Warner had team highs with 12 total stops, seven solo tackles and a tackle for loss in Week 5 against the Arizona Cardinals.

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The New England Patriots' defense tallied one interception and one fumble recovery while allowing just 15 points during Sunday's Week 5 loss to the Miami Dolphins. Christian Gonzalez registered the pick while New England's special teams unit was responsible for the fumble on a blocked punt. Miami also botched a field goal attempt on a bad snap, but the Dolphins were able to pounce on top of the loose ball, effectively ending the drive without crediting New England for a fumble recovery. Elsewhere on the stat sheet, the Patriots registered three sacks, five tackles for loss, and 372 yards allowed. Their road gets much tougher heading into a Week 6 clash with C.J. Stroud's Houston Texans.

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Arizona Cardinals S Budda Baker ended up with 12 total stops and eight solo tackles in Week 5 against the San Francisco 49ers.

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Jacksonville Jaguars tight end Brenton Strange caught one of the two passing touchdowns quarterback Trevor Lawrence had in a 37-34 win over the Indianapolis Colts. Strange finished with 24 yards on four catches. The young tight end now has two touchdowns and 120 yards on the season. It seemed like Evan Engram (hamstring) had a decent chance of returning in Week 5, but that was not the case, so the second-year pro got the start for the third straight game. This could be the last start Strange gets, so his fantasy managers should be happy with his fantasy output over the past few weeks given his status as a backup tight end. If Engram were to miss even more time, Strange would continue to be a solid streaming option. The Jaguars face off against the Chicago Bears in London in Week 6, where it will be interesting to see how involved Strange is if Engram does return.

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New England Patriots wide receiver Ja'Lynn Polk converted six targets into just one catch for 13 yards during Sunday's Week 5 loss to the Miami Dolphins. While the rookie's fantasy output was disappointing, managers should feel optimistic about some of his underlying statistics. For starters, Polk has 13 targets over the last two weeks combined, which is the highest mark on the team during that span. He also played 100 percent of snaps on Sunday, becoming the first Patriots wide receiver to play every offensive snap in a single game this season. (No New England wide receiver previously eclipsed the 85-percent mark.) Furthermore, he came very close to catching his second career touchdown pass, missing out on the go-ahead score by mere inches as his foot barely landed out of bounds. All in all, Polk has emerged as one of Jacoby Brissett's favorite weapons as of late. While it hasn't led to noteworthy fantasy production, he's still on the radar as an up-and-coming pass-catcher in the New England offense. He's worth monitoring in deeper leagues as the season carries on. His next chance to leave an impression will come in Week 6 when the Patriots host the Houston Texans.

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Carolina Panthers running back Chuba Hubbard reeled off another excellent performance in the team's 36-10 loss to the Chicago Bears. Quarterback Andy Dalton threw for just 136 scoreless yards Sunday -- and was eventually benched for second-year QB Bryce Young in the waning minutes of regulation -- but that didn't stop Hubbard from ripping off another big stat line. The 25-year-old toted the rock 13 times, churning out 97 yards and a touchdown on the ground while hauling in all four of his targets for -2 "additional" yards. It marks the fourth-year back's third-straight outing with a touchdown and four in a row with at least four catches. Additionally, he was just three yards shy of eclipsing the century mark in his third consecutive game. The former fourth-round pick has been a pleasant surprise of fantasy output over the last few weeks. However, the question arises of his role if and when quarterback Bryce Young regains control of this offense. When that happens is anyone's guess, but until then, Hubbard can be considered a high-end RB2 with upside. He'll have a harder time reaching those marks against the Falcons in Week 6, but he is a must-start option.

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New England Patriots tight end Hunter Henry caught two of four targets for 32 yards through the air during Sunday's Week 5 loss to the Miami Dolphins. Henry has caught just two passes in four of his five games this season, with the lone exception being a somewhat anomalous eight-catch, 109-yard outburst back in Week 2. Despite playing a season-high 93.3 percent of snaps on Sunday, the 29-year-old veteran continues to have his fantasy value limited within the Patriots' struggling offense. He remains off the fantasy radar in most leagues ahead of a Week 6 clash versus the Houston Texans.

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Quarterback Brock Purdy and the San Francisco 49ers fell short in a 24-23 loss to the Arizona Cardinals on Sunday in Santa Clara. He finished with 19 completions of 35 attempts for 244 yards, one touchdown, and two interceptions. Purdy also gained 33 rushing yards on four scrambles. While fantasy managers would much rather see more passing touchdowns, it's worth noting that he's been much more adept at contributing on the ground this year. After today, he's averaging 21.6 yards rushing per game, much higher than his nine yards per carry last year. The interceptions certainly stung in this one, but Purdy was a victim of bad luck as one of his interceptions was batted at the line and the other popped high into the air when he was hit as he threw. The third-year pro showed a renewed rapport with receiver Brandon Aiyuk, who he targeted 12 times for 8 receptions and 147 yards. Purdy has a short turnaround as he hits the road to face the Seattle Seahawks for the first time this year on Thursday Night Football.

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New York Giants kicker Greg Joseph continued his perfect streak in Sunday's 29-20 victory over the Seattle Seahawks, going 3-for-3 on field goals for the second straight week. Joseph drilled a long of 38 yards and added two extra points, contributing 11 total points to the Giants' win. His reliability on special teams has been crucial, as he remains flawless through two weeks, consistently converting his opportunities. With his 100% field goal percentage intact from the past two games, Joseph is shaping up as a strong fantasy kicker option, especially for teams seeking steady production.

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