Guest of the League
Lineup Changes
51st - Carlos Samora
| Benched | RB | Zack Moss CIN | Owner | Sat Oct 5 9:15pm ET |
| Started | RB | Alexander Mattison LV | Owner | Sat Oct 5 9:15pm ET |
| Started | D/ST | Denver Broncos DEN | Owner | Thu Oct 3 12:10am ET |
AnonDYN2 - Brian Conti
| Benched | WR | Zay Flowers BAL | Owner | Thu Oct 3 12:11am ET |
| Started | WR | Chris Olave NO | Owner | Thu Oct 3 12:11am ET |
| Benched | RB | David Montgomery DET | Owner | Tue Oct 1 11:29pm ET |
| Benched | TE | Dallas Goedert PHI | Owner | Tue Oct 1 11:29pm ET |
| Started | RB | Josh Jacobs GB | Owner | Tue Oct 1 11:29pm ET |
| Started | TE | Trey McBride ARI | Owner | Tue Oct 1 11:29pm ET |
Bulldozers - Frank Randazzo
| Benched | WR | Romeo Doubs GB | Owner | Sun Oct 6 7:21am ET |
| Started | WR | Dontayvion Wicks GB | Owner | Sun Oct 6 7:21am ET |
| Benched | RB | Jonathan Taylor IND | Owner | Tue Oct 1 10:09am ET |
| Started | RB | Rico Dowdle DAL | Owner | Tue Oct 1 10:09am ET |
Defenders - TF
| Started | WR | Jaylen Waddle MIA | Owner | Sun Oct 6 12:37pm ET |
| Started | RB | Jaylen Wright MIA | Owner | Sun Oct 6 12:37pm ET |
| Benched | WR | Malik Nabers NYG | Owner | Sun Oct 6 12:37pm ET |
| Benched | RB | Jaylen Warren PIT | Owner | Sun Oct 6 12:37pm ET |
| Started | K | Younghoe Koo ATL | Owner | Thu Oct 3 9:42am ET |
| Started | TE | Cade Otton TB | Owner | Thu Oct 3 9:42am ET |
| Started | RB | Jaylen Warren PIT | Owner | Thu Oct 3 9:42am ET |
| Benched | K | Cameron Dicker LAC | Owner | Thu Oct 3 9:42am ET |
| Benched | TE | Mike Gesicki CIN | Owner | Thu Oct 3 9:42am ET |
| Benched | RB | Jaylen Wright MIA | Owner | Thu Oct 3 9:42am ET |
| Started | D/ST | Baltimore Ravens BAL | Owner | Wed Oct 2 9:26pm ET |
| Started | RB | Austin Ekeler WAS | Owner | Wed Oct 2 9:26pm ET |
| Benched | D/ST | Cleveland Browns CLE | Owner | Wed Oct 2 9:26pm ET |
| Benched | RB | J.K. Dobbins LAC | Owner | Wed Oct 2 9:26pm ET |
Fire - Rick Purifoy
| Benched | RB | Devin Singletary NYG | Owner | Sat Oct 5 11:52pm ET |
| Benched | RB | Zamir White LV | Owner | Sat Oct 5 11:52pm ET |
| Started | RB | Braelon Allen NYJ | Owner | Sat Oct 5 11:52pm ET |
| Started | RB | Tyrone Tracy Jr. NYG | Owner | Sat Oct 5 11:52pm ET |
Gay Cowboys - Brett Knapp
| Benched | RB | Rhamondre Stevenson NE | Owner | Sun Oct 6 6:00am ET |
| Started | RB | Antonio Gibson NE | Owner | Sun Oct 6 6:00am ET |
| Benched | QB | Jared Goff DET | system | Sun Oct 6 4:31am ET |
| Started | QB | Caleb Williams CHI | system | Sun Oct 6 4:31am ET |
| Started | WR | Wan'Dale Robinson NYG | system | Sun Oct 6 4:31am ET |
| Benched | WR | Amon-Ra St. Brown DET | system | Sun Oct 6 4:31am ET |
Ghetto Superstars - Ol' Dirty Bastard
| Benched | QB | Justin Herbert LAC | Owner | Wed Oct 2 8:36pm ET |
| Started | QB | Jordan Love GB | Owner | Wed Oct 2 8:36pm ET |
| Benched | RB | Jahmyr Gibbs DET | Owner | Wed Oct 2 8:36pm ET |
| Benched | WR | Calvin Ridley TEN | Owner | Wed Oct 2 8:36pm ET |
| Started | RB | Javonte Williams DEN | Owner | Wed Oct 2 8:36pm ET |
| Started | WR | Keon Coleman BUF | Owner | Wed Oct 2 8:36pm ET |
Kid Dynomite - Jeff Pitts
| Benched | QB | Jalen Hurts PHI | Owner | Tue Oct 1 9:24am ET |
| Benched | RB | Saquon Barkley PHI | Owner | Tue Oct 1 9:24am ET |
| Benched | WR | Rashee Rice KC | Owner | Tue Oct 1 9:24am ET |
| Started | QB | Justin Fields PIT | Owner | Tue Oct 1 9:24am ET |
| Started | RB | Bucky Irving TB | Owner | Tue Oct 1 9:24am ET |
| Started | RB | Kenneth Walker III SEA | Owner | Tue Oct 1 9:24am ET |
Let Dak Cook - Kevin
| Benched | WR | Tyler Johnson LAR | Owner | Tue Oct 1 8:53am ET |
| Benched | TE | Kyle Pitts ATL | Owner | Tue Oct 1 8:53am ET |
| Benched | D/ST | Miami Dolphins MIA | Owner | Tue Oct 1 8:53am ET |
| Started | WR | Deebo Samuel SF | Owner | Tue Oct 1 8:53am ET |
| Started | TE | George Kittle SF | Owner | Tue Oct 1 8:53am ET |
| Started | D/ST | Chicago Bears CHI | Owner | Tue Oct 1 8:53am ET |
Punchfade D - James Malia
| Started | WR | Jakobi Meyers LV | Owner | Sun Oct 6 1:22am ET |
| Benched | WR | Allen Lazard NYJ | Owner | Sun Oct 6 1:22am ET |
| Started | WR | Jordan Whittington LAR | Owner | Wed Oct 2 7:15pm ET |
| Benched | WR | Jakobi Meyers LV | Owner | Wed Oct 2 7:15pm ET |
| Started | WR | Allen Lazard NYJ | Owner | Tue Oct 1 8:47pm ET |
| Benched | WR | Ladd McConkey LAC | Owner | Tue Oct 1 8:47pm ET |
| Started | D/ST | Houston Texans HOU | Owner | Tue Oct 1 8:30am ET |
| Benched | D/ST | Buffalo Bills BUF | Owner | Tue Oct 1 8:30am ET |
| Started | D/ST | Buffalo Bills BUF | Owner | Tue Oct 1 8:25am ET |
| Benched | D/ST | Houston Texans HOU | Owner | Tue Oct 1 8:25am ET |
Tua-Infinity & Bijan - Michael Chaffee
| Benched | TE | Chigoziem Okonkwo TEN | Owner | Wed Oct 2 8:41pm ET |
| Started | TE | David Njoku CLE | Owner | Wed Oct 2 8:41pm ET |
WebBull - Timothy Dillon
| Benched | WR | Khalil Shakir BUF | Owner | Sun Oct 6 9:31am ET |
| Started | WR | Josh Downs IND | Owner | Sun Oct 6 9:31am ET |
| Started | RB | Trey Sermon IND | Owner | Thu Oct 3 11:33am ET |
| Started | D/ST | Seattle Seahawks SEA | Owner | Thu Oct 3 11:33am ET |
| Benched | TE | Sam LaPorta DET | Owner | Wed Oct 2 2:49pm ET |
| Started | TE | Colby Parkinson LAR | Owner | Wed Oct 2 2:49pm ET |
