Guest of the League
Lineup Changes
5.4 Kona Ice Guys SF - Kenneth Jones
| Benched | WR | Jerry Jeudy CLE | Owner | Tue Nov 5 6:13pm ET |
| Started | WR | Quentin Johnston LAC | Owner | Tue Nov 5 6:13pm ET |
Ballbusters 6 - Quinton Fletcher
| Benched | QB | Caleb Williams CHI | Owner | Tue Nov 5 4:18pm ET |
| Benched | WR | Jaxon Smith-Njigba SEA | Owner | Tue Nov 5 4:18pm ET |
| Started | QB | C.J. Stroud HOU | Owner | Tue Nov 5 4:18pm ET |
| Started | WR | Jalen Coker CAR | Owner | Tue Nov 5 4:18pm ET |
Canal Rat* - DJ Davis
| Benched | QB | Geno Smith SEA | Owner | Wed Nov 6 12:13am ET |
| Benched | RB | Kenneth Walker III SEA | Owner | Wed Nov 6 12:13am ET |
| Benched | WR | Jayden Reed GB | Owner | Wed Nov 6 12:13am ET |
| Started | RB | Tank Bigsby JAX | Owner | Wed Nov 6 12:13am ET |
| Started | RB | Tyjae Spears TEN | Owner | Wed Nov 6 12:13am ET |
| Started | WR | Sterling Shepard TB | Owner | Wed Nov 6 12:13am ET |
Centaurian - Cam Teeter
| Benched | TE | Jonnu Smith MIA | Owner | Thu Nov 7 7:19am ET |
| Started | TE | Mike Gesicki CIN | Owner | Thu Nov 7 7:19am ET |
| Benched | TE | Cole Kmet CHI | Owner | Wed Nov 6 5:54pm ET |
| Started | TE | Jonnu Smith MIA | Owner | Wed Nov 6 5:54pm ET |
| Benched | WR | Jakobi Meyers LV | Owner | Wed Nov 6 5:54pm ET |
| Started | WR | Brian Thomas Jr. JAX | Owner | Wed Nov 6 5:54pm ET |
FSU 5 - J Myers
| Benched | RB | Devin Singletary NYG | Owner | Wed Nov 6 5:30pm ET |
| Started | RB | Rico Dowdle DAL | Owner | Wed Nov 6 5:30pm ET |
| Started | WR | Jauan Jennings SF | Owner | Wed Nov 6 5:30pm ET |
He Hate Me SF1 - Michael Marrazzo
| Benched | RB | Josh Jacobs GB | Owner | Tue Nov 5 6:55pm ET |
| Benched | TE | David Njoku CLE | Owner | Tue Nov 5 6:55pm ET |
| Started | RB | James Conner ARI | Owner | Tue Nov 5 6:55pm ET |
| Started | TE | T.J. Hockenson MIN | Owner | Tue Nov 5 6:55pm ET |
Lowly K-Gregorians - Kyle Gregory
| Benched | RB | Antonio Gibson NE | Owner | Tue Nov 5 4:29pm ET |
| Started | RB | Jaylen Warren PIT | Owner | Tue Nov 5 4:29pm ET |
| Benched | WR | Andrei Iosivas CIN | Owner | Tue Nov 5 4:28pm ET |
| Started | WR | Jameson Williams DET | Owner | Tue Nov 5 4:28pm ET |
Mister Rodgers Neighborhood - Brian Foley
| Benched | QB | Dak Prescott DAL | Owner | Thu Nov 7 11:30am ET |
| Benched | WR | Jonathan Mingo DAL | Owner | Thu Nov 7 11:30am ET |
| Started | WR | Deebo Samuel SF | Owner | Thu Nov 7 11:30am ET |
| Started | TE | George Kittle SF | Owner | Thu Nov 7 11:30am ET |
Scooter19 - Scott Christian
| No starting lineup changes performed this week. |
SF06 X - YouHateMe
| Benched | WR | Tee Higgins CIN | Owner | Wed Nov 6 10:28pm ET |
| Started | WR | Amari Cooper BUF | Owner | Wed Nov 6 3:21pm ET |
| Benched | WR | Calvin Austin III PIT | Owner | Wed Nov 6 3:21pm ET |
| Started | TE | Dallas Goedert PHI | Owner | Wed Nov 6 3:20pm ET |
| Started | WR | Tee Higgins CIN | Owner | Tue Nov 5 12:22pm ET |
| Started | WR | Calvin Austin III PIT | Owner | Tue Nov 5 12:22pm ET |
| Started | RB | Tyler Allgeier ATL | Owner | Tue Nov 5 12:22pm ET |
| Benched | TE | Brock Bowers LV | Owner | Tue Nov 5 12:22pm ET |
| Benched | WR | Tyler Lockett SEA | Owner | Tue Nov 5 12:22pm ET |
| Benched | WR | Romeo Doubs GB | Owner | Tue Nov 5 12:22pm ET |
| Benched | RB | Alexander Mattison LV | Owner | Tue Nov 5 12:22pm ET |
The Empire SF1 - Bryan Garciga
| Benched | RB | Nick Chubb CLE | Owner | Tue Nov 5 8:57am ET |
| Benched | WR | Jalen McMillan TB | Owner | Tue Nov 5 8:57am ET |
| Started | RB | Bucky Irving TB | Owner | Tue Nov 5 8:57am ET |
| Started | WR | George Pickens PIT | Owner | Tue Nov 5 8:57am ET |
Whack - Matt Rutherford
| Benched | WR | Elijah Moore CLE | Owner | Tue Nov 5 8:01am ET |
| Benched | WR | Xavier Worthy KC | Owner | Tue Nov 5 8:01am ET |
| Started | QB | Brock Purdy SF | Owner | Tue Nov 5 8:01am ET |
| Started | WR | Zay Flowers BAL | Owner | Tue Nov 5 8:01am ET |
