Indianapolis Colts running back Trey Sermon (collarbone) was held out of Wednesday's practice but was a full participant just a day later on Thursday. Sermon was a popular waiver-wire pickup last week after Jonathan Taylor suffered a high-ankle sprain in the Week 4 win over the Indianapolis Colts. Taylor did not play in the Week 5 loss to the division-rival Jacksonville Jaguars, and Sermon took advantage as the lead back to record 10 carries for 38 yards and a touchdown while adding six catches for an extra 25 yards. Taylor has not practiced this week and appears headed for a second straight absence, which will put Sermon back into flex territory against the Titans. The 25-year-old won't have as much fantasy upside, though, against a Titans defense allowing the 22nd-most half-PPR points to RBs through five weeks. The impending return of quarterback Anthony Richardson (oblique) is also probably bad news for Sermon's rushing chances.

From RotoBaller

Updating a previous report, Indianapolis Colts quarterback Anthony Richardson (oblique) was a full participant in Thursday's practice and was looking spry after being limited on Wednesday. Richardson injured his oblique in the Week 4 win over the Pittsburgh Steelers and didn't suit up for the Week 5 loss to the division-rival Jacksonville Jaguars. With a full practice under his belt this week, the 22-year-old second-year signal-caller is trending toward returning for this Sunday's divisional clash with the Tennessee Titans against a tough secondary. However, fantasy managers shouldn't be looking to throw him immediately back into starting lineups if he's active in Week 6, especially if he's without running back Jonathan Taylor (ankle) and receivers Michael Pittman Jr. (back) and Josh Downs (toe). Richardson has been a disappointment through four games in 2024 as both a runner and a passer.

From RotoBaller

San Francisco 49ers wide receiver Chris Conley (oblique) is officially active for the Thursday night divisional showdown against the Seattle Seahawks at Lumen Field to kick off Week 6 action. Conley came into the game listed as questionable, but he will suit up. Meanwhile, cornerback Charvarius Ward (knee) is inactive and won't play. Conley is making his return after missing the Week 5 loss to the division-rival Arizona Cardinals. The 31-year-old veteran has caught only one pass on three targets for a four-yard gain in four games played in 2024. Fantasy managers can continue to ignore Conley as he serves as receiver depth in San Francisco. Conley's return in Week 6 could mean less opportunities for rookie Jacob Cowing and Ronnie Bell.

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Philadelphia Eagles wide receivers A.J. Brown (hamstring) and DeVonta Smith (concussion) are both on track to return to action in Week 6 against the Cleveland Browns after putting in a second straight day with a full practice on Thursday. Brown hasn't played since catching half of his 10 targets for 119 yards and a touchdown in the Week 1 win over the Green Bay Packers in Brazil, but he's made nice progress coming out of the bye week and should be returned to all starting fantasy lineups for a tilt against Cleveland this Sunday in Philly. Smith suffered a concussion in Week 3 and was held out of the Week 4 loss to the Tampa Bay Buccaneers. He, too, should be returned to all fantasy lineups, although he still needs to gain final clearance from the concussion protocol. The return of both Brown and Smith is bad news for tight end Dallas Goedert but is great news for quarterback Jalen Hurts' fantasy value.

From RotoBaller

The Athletic's Matt Barrows writes that San Francisco 49ers quarterback Brock Purdy and the team clearly aren't looking for running back Jordan Mason as a receiver out of the backfield. Mason is still building his chemistry with Purdy as the team's lead back in 2024 with Christian McCaffrey (Achilles) injured. No RB who has run at least 50 pass routes has been targeted less than Mason this year. A lot of that could have to do with the fact that the Niners don't actually have a third-down option at the position. Although Mason has just seven receptions for 66 yards in five games this year, he's the RB5 in half-PPR scoring into the team's Thursday night divisional showdown against the Seattle Seahawks at Lumen Field. Mason lost the first fumble of his career in the Week 5 loss to the Arizona Cardinals but still had 89 rushing yards on 14 carries. He's a must-start in Week 6 on Thursday night in fantasy.

From RotoBaller

Atlanta Falcons running back Bijan Robinson (hamstring) was added to the Week 6 injury report after putting in a limited practice on Thursday. Robinson was a full-go on Wednesday. His downgrade on Thursday is most likely just the Falcons giving him a little rest as the team prepares to take on the division-rival Carolina Panthers in Week 6. The 22-year-old was also listed with a hamstring injury before last Thursday's win over the Tampa Bay Buccaneers, but he played and handled 15 touches for 77 scrimmage yards. Drafted in the first round in fantasy drafts this year, Robinson has been a bust so far as the RB21 in half-PPR scoring through the first five weeks. However, he won't have a better bounce-back opportunity this weekend than against the 1-4 Panthers, as they have allowed the most points to opposing RBs this year. Bijan is a must-start in all lineups.

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Atlanta Falcons wide receiver Darnell Mooney (knee) put in a limited practice on Thursday for the second straight day this week. If Mooney doesn't upgrade to a full practice on Friday, he could be listed on the Week 6 injury report as questionable to play this Sunday against the division-rival Carolina Panthers. However, there doesn't appear to be too much worry that the 26-year-old is in danger of missing this weekend's game after he went off for nine catches, 105 yards and two touchdowns in the Thursday night win over the division-rival Tampa Bay Buccaneers last week. Mooney has surprisingly been the WR15 in half-PPR scoring through five weeks with 24 catches for 330 yards and three touchdowns. With quarterback Kirk Cousins now looking more comfortable in this offense, Mooney's fantasy stock is on the rise and he should be considered an attractive WR2/3 in Week 6 against Carolina.

From RotoBaller

Denver Broncos wide receiver Josh Reynolds (hand) missed his second straight practice this week on Thursday due to a hand injury. Reynolds' status for the Week 6 contest versus the division-rival Los Angeles Chargers this Sunday is firmly up in the air. He'll likely need to practice in some fashion on Friday to avoid being ruled out entirely. If Reynolds is limited or out entirely this weekend, look for the likes of Lil'Jordan Humphrey, Marvin Mims Jr. and rookie Troy Franklin to battle for more targets behind WR1 Courtland Sutton. The 29-year-old Reynolds was much more involved in the first several games of the 2024 season. During the team's three-game winning streak, Reynolds only has three catches on six targets for 45 yards, although he did find the end zone for the first time this year in the Week 5 win over the Las Vegas Raiders. Reynolds belongs on the waiver wire in most formats.

From RotoBaller

Dynasty | The Saints will start Spencer Rattler at quarterback this week. Dynasty Analysis: Rattler gets the nod over Jake Haener and will have a chance to make an impression while Derek Carr is sidelined with an oblique injury. Once one of the highest profile college quarterbacks, Rattler's journey to a starting nod is filled with ups, downs, disappointments, and general weirdness. In the end, he'll get a chance to show he belongs in the NFL. Expectations should be tempered as rookies tend to struggle, but this is obviously a big development as Rattler gets an opportunity much earlier than expected to show he could be the Saints quarterback of the future. He should be on dynasty rosters everywhere at this point.

Cleveland Browns TE David Njoku (ankle, knee) was limited during practice Thursday, Oct. 10.

Fantasy Spin: Njoku appears to be questionable for the Week 6 game, so fantasy players will need to check on his status after the last practice of the week. He is a weekly starting option when healthy, but fantasy players will need a backup plan ready in case he sits out.

From TheHuddle

Cleveland Browns WR Amari Cooper (non-injury) fully participated in practice Thursday, Oct. 10.

Fantasy Spin: Cooper has been the main option of the Browns this season and should continue to see a good amount of targets in Week 6. He can be at least a flex option in fantasy leagues.

From TheHuddle

Cincinnati Bengals tight end Mike Gesicki (hamstring) did not practice on Wednesday but returned to a limited session on Thursday. Gesicki's status is still up in the air for Week 6 against the New York Giants on Sunday night, but his return to practice on Thursday is a good sign for his availability this weekend. If the 29-year-old carries a questionable status into the weekend, he'll be a much more risky fantasy play on Sunday night. In his first year with the Bengals, Gesicki has caught 17 of his 21 targets for 178 yards and no touchdowns through his first five games. He's currently the TE15 in half-PPR scoring and will most likely need to find the end zone to jump up into TE1 territory. If Gesicki doesn't end up playing in Week 6 or is limited, rookie Erick All Jr. would likely work as the primary pass-catching tight end and would have more TE2 streaming appeal.

From RotoBaller

Barring a setback, signs are pointing toward Denver Broncos rookie running back Audric Estime (ankle) being activated from Injured Reserve for Sunday's Week 6 divisional matchup against the Los Angeles Chargers, according to a source. Estime missed the required four games while on IR and was designated to return on Wednesday. He was listed as a full practice participant for the second straight day this week on Thursday. This isn't exactly what Javonte Williams' fantasy managers want to hear, even though he should continue to be Denver's lead back this weekend. Both Williams and Jaleel McLaughlin had more room to work in the Week 5 win over the division-rival Las Vegas Raiders, but don't be surprised if the 21-year-old Estime carves out a small role once he gets up to speed. Estime is really only worth stashing in dynasty/keeper leagues for now.

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Cleveland Browns RB Nick Chubb (knee) was limited during practice Thursday, Oct. 10.

Fantasy Spin: Fantasy players should monitor the situation to see if Chubb will be activated before the Week 6 game. He likely will see a limited workload once he returns and may not be a starting fantasy option right away.

From TheHuddle

Cleveland Browns RB D'Onta Foreman (ankle) was limited during practice Thursday, Oct. 10.

Fantasy Spin: Foreman appears to have a chance to play this week, so fantasy players should keep an eye on the situation. He has been sharing playing time with Jerome Ford and could be a possible flex option in deeper leagues if he is cleared.

From TheHuddle

Cincinnati Bengals running backs Zack Moss (foot) and Chase Brown (quadriceps) were both limited in Thursday's practice. Moss did not practice on Wednesday, while Brown is a new addition to the Week 6 injury report. Moss' ability to return to practice a day later is good news for his status this week, but the Bengals' backfield is worth watching over the next couple of days. If one or both of Moss and Brown are questionable to play, fantasy managers will have some tough decisions to make with the Bengals facing the New York Giants on Sunday night. Fantasy managers will want to check back for Friday's final injury report for more clarity on the situation. If one or both are up in the air to face the G-Men, Trayveon Williams could be looking at a much bigger workload in Week 6. Moss checks in as the RB20 in half-PPR this year, while Brown isn't far behind as the RB26.

From RotoBaller

Green Bay Packers DT Devonte Wyatt (ankle) and TE Luke Musgrave (ankle) did not participate in practice Thursday, Oct. 10. CB Jaire Alexander (groin), DT Kenny Clark (toe), LB Edgerrin Cooper (hip), DT Jonathan Ford (calf), OG Elgton Jenkins (knee), OT Jordan Morgan (shoulder) and CB Carrington Valentine (ankle) were limited during practice. S Zayne Anderson (elbow), DE Arron Mosby (shoulder) and OT Zach Tom (shoulder) fully participated in practice.

From TheHuddle

The NFL placed New England Patriots safety Jabrill Peppers (shoulder) on the commissioner's exempt list on Wednesday. Peppers may not practice or attend games while he's on the list. Peppers plead guilty on Monday after he was arrested last Saturday in Massachusetts on strangulation and drug-possession charges. The 29-year-old won't be available to the Patriots' defense for the foreseeable future. The former 25th overall pick by the Cleveland Browns in 2017 out of Michigan is in his third year with the Patriots and had 23 tackles (11 solo), an interception and two pass breakups in his four games played before being suspended due to off-the-field transgressions. New England's secondary will certainly be more vulnerable without Peppers, starting this Sunday against the Houston Texans and their explosive aerial assault.

From RotoBaller

Green Bay Packers head coach Matt LaFleur said that tight end Luke Musgrave (ankle) "more than likely" will land on Injured Reserve due to his ankle injury, which will sideline him for at least four games. If the Packers put Musgrave on IR officially before the Week 6 game against the Arizona Cardinals this Sunday, he won't be eligible to return until after the Week 10 bye for a Week 11 divisional contest against the Chicago Bears. The 24-year-old was active in the Week 5 win over the Los Angeles Rams but didn't actually play. With Musgrave out for the foreseeable future, it's more good news for Tucker Kraft (groin), who scored two touchdowns last Sunday against the Rams. Ben Sims and John FitzPatrick will now be the backups to Kraft. Musgrave had just five catches on seven targets for 22 yards and no touchdowns in four games this year before his ankle injury.

From RotoBaller

New England Patriots RB Rhamondre Stevenson (foot) did not practice on Thursday, Oct. 10. Also, S Kyle Dugger (ankle), WR Kendrick Bourne (knee), DT Davon Godchaux (elbow), CB Marcus Jones (groin), C Nick Leverett (ankle), WR K.J. Osborn (shoulder), OG Layden Robinson (ankle, wrist), LB Sione Takitaki (knee), CB Marco Wilson (groin) and CB Isaiah Bolden (hamstring) were limited and OT Vederian Lowe (knee), LB Anfernee Jennings (shoulder) and CB Jonathan Jones (shoulder) practiced in full.

From TheHuddle