Indianapolis Colts head coach Shane Steichen said running back Jonathan Taylor (ankle) will not practice on Wednesday after he missed the Week 5 loss to the division-rival Jacksonville Jaguars with a minor high-ankle sprain. Although Taylor's ankle sprain isn't considered too serious, he's no lock to play in Week 6 against the division-rival Tennessee Titans this Sunday, and a DNP to begin the week isn't a great sign. If the 25-year-old doesn't make much progress in practice this week and is unable to play this weekend, Trey Sermon will once again serve as Indy's lead back, with Tyler Goodson backing him up. In the loss to Jacksonville on Sunday, Sermon played 59% of the offensive snaps and had 10 carries for 38 yards and his second touchdown of the year, adding six catches on six targets for an additional 25 yards. At worst, Sermon will be a plug-and-play RB3/flex option again for fantasy managers if Taylor misses another game.

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New England Patriots S Jabrill Peppers was placed on the commissioner's exempt list on Wednesday, Oct. 9.

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Free-agent QB Trevor Siemian (Jets) was signed to the Tennessee Titans' practice squad on Wednesday, Oct. 9. Also, OT Leroy Watson was promoted from the practice squad to the 53-man roster.

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Jacksonville Jaguars LB Foyesade Oluokun (foot) is expected back in Week 7 or 8, head coach Doug Pederson said on Wednesday, Oct. 9.

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Cleveland Browns QB Deshaun Watson being benched isn't under consideration right now, head coach Kevin Stefanski said on Wednesday, Oct. 9.

Fantasy Spin: Watson has been the definition of a dumpster fire and the Browns insist on continuing to try and justify his contract when everyone can clearly see it's a disaster. That's apparently more important to Cleveland than actually having a chance to win. Watson remains an afterthought for fantasy purposes and his existence destroys any value Browns pass-catchers could've had.

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Arizona Cardinals WR Chris Moore is being released, per source on Wednesday, Oct. 9.

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Houston Texans wide receiver Nico Collins (hamstring) is being placed on the Injured Reserve list on Wednesday, meaning he will have to miss at least the next four games. The star wideout suffered a hamstring injury after catching a 67-yard touchdown pass in the Week 5 win over the Buffalo Bills. Collins was No. 2 in total PPR fantasy points heading into Week 5, so this is obviously a crushing blow for his fantasy managers. He will be ineligible to return until Week 10 against the Detroit Lions. With Collins sidelined, Stefon Diggs could be a top-five fantasy wideout during his absence, and Tank Dell, who has struggled so far, will likely have a WR2/WR3 outlook in most matchups. Deep-league fantasy managers might want to kick tires on veteran Robert Woods, but youngsters Xavier Hutchinson and John Metchie III could become fantasy factors. Tight end Dalton Schultz could also benefit in this situation.

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Las Vegas Raiders wide receiver Davante Adams (hamstring) is unlikely to play against the Pittsburgh Steelers, according to ESPN's Jeremy Fowler. The hamstring issue may be more of an excuse at this point to keep Adams off the field while the Raiders search for a trade partner. A report earlier this week stated that Adams is nearing full health. The Jets, Saints, and Steelers seem to be the teams pursuing Adams the hardest. However, the Saints just lost Derek Carr (oblique) for a few weeks. The Jets fired their head coach. Other teams don't seem as eager to match the Raiders' asking price. This will be the third straight game Adams has missed. He likely won't see the field again until he's on a different roster.

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Las Vegas Raiders WR Davante Adams (hamstring) is expected to be out for Week 6 against the Pittsburgh Steelers.

Fantasy Spin: Jakobi Meyers has turned 19 targets into 11 grabs for 121 yards the last two weeks. He and TE Brock Bowers are really the only Raiders pass-catchers worth using. Meyers is a flex option, and Bowers is a solid TE1.

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Detroit Lions running back Jahmyr Gibbs has failed to catch a pass in the last two games (although he did get 20 yards and a receiving touchdown on a lateral in Week 3). It's the first time in his young career that he's failed to log a reception in back-to-back games. Thankfully for fantasy football, he's averaging 13.5 carries and 71 rushing yards per game and has failed to score a touchdown just once. The Dallas Cowboys have allowed 17 receptions to running backs this season, the fifth-lowest mark in the league. However, the 222 yards they've given up to the position is the sixth-most. Even if Gibbs can't break off a long reception, the Cowboys' defense is banged up and has been susceptible against the run. Gibbs and his counterpart David Montgomery should be viewed as top-12 running backs this week.

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Detroit Lions running back David Montgomery looks to continue his scoring ways against the Dallas Cowboys defense in Week 6. The veteran runner has scored a touchdown in all four of Detroit's games this season, despite splitting duties with Jahmyr Gibbs. He's averaging 15.75 carries per game. The Cowboys have allowed the seventh-most fantasy points to running backs and surrendered six touchdowns on the ground through five games. The defensive front-seven is banged up and the Lions' elite offensive line should have little issue opening holes for Monty and Gibbs. Both backs are ranked as RB1s this week in what should be a high-scoring affair in Texas.

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Free agent pass rusher Shaq Lawson has signed with the Carolina Panthers. The veteran visited the team on Tuesday and left with a new contract. It's Lawson's first time out of the AFC East. He began his career with Buffalo in 2016, played one season each in New York and Miami, and spent the last two seasons in Buffalo again. The Panthers are desperate for defensive playmakers. Due to injuries and bad play, Carolina is one of the worst defenses in football. They have recorded six sacks in five games in 2024. Lawson logged one sack in 16 games last season.

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San Francisco 49ers linebacker Fred Warner (ankle) was designated a limited participant in Tuesday's walk-through practice. The 49ers travel to Seattle for Thursday Night Football and haven't held a full practice this week. Warner practiced just once last week, and he dealt with this same ankle injury and still played. The expectation is that Warner will be active for the divisional tilt. The 49ers' defense is banged up, the most notable of which is Talanoa Hufanga (wrist), who will miss a few weeks. Warner is the linebacker with the best odds to win NFL Defensive Player of the Year.

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Free agent wide receiver Dante Pettis visited the Dallas Cowboys on Tuesday with the hopes of landing a new contract. Former Jet Denzel Mims also tried out for Dallas. The Cowboys are looking to bolster their wide receiver depth with Brandin Cooks (knee) on injured reserve and set to miss at least three more games. Pettis camped with the Chicago Bears this summer but failed to make the final roster. He last appeared in a regular season game in 2022, catching 19 passes for 245 yards with the Bears. Even if Dallas signs one of these receivers, they won't be on the fantasy football radar in any format.

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Cleveland Browns TE David Njoku (knee) played only 26 of 62 snaps before leaving the game early in Week 5 versus the Washington Commanders.

Fantasy Spin: Njoku, who was making his return from the high-ankle sprain he suffered in Week 1, did not return to the game. No announcement regarding how much time he is expected to miss has been made yet, but it is not a great sign that the team worked out several tight ends on Tuesday. Fantasy managers should expect to be without his services for at least Week 6 against the Philadelphia Eagles.

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Cleveland Browns CB Denzel Ward (hamstring), S Grant Delpit (head), C Ethan Pocic (knee), DE Ogbo Okoronkwo (illness) and LS Charley Hughlett (rib) left the game early and did not return in Week 5 against the Washington Commanders. S Rodney McLeod (face) also made an early exit but returned to the contest.

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Las Vegas Raiders wide receiver Davante Adams has been the hottest name in the trade market over the last week or two. The veteran wideout has been sidelined since Week 3 due to a hamstring injury, but it doesn't appear to be serious. That being said, Adams figures to be dealt relatively soon. The New York Jets and New Orleans Saints were the favorites to land the superstar wideout. However, those trade talks may have slowed down, according to Adam Schefter. The Jets have fired head coach Robert Saleh and their season is headed in the wrong direction quickly. While the Saints just lost quarterback Derek Carr (oblique) for likely multiple weeks, which could put their season in jeopardy. Both the Jets and Saints aren't likely to give up assets to acquire Adams if they aren't going to be competitive this season. The assumption is both teams probably still have interest, but it sounds like trade discussions have slowed down a bit.

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Seattle Seahawks defensive tackle Byron Murphy II (hamstring) missed practice for the second straight day on Tuesday. It's worth noting that the organization held a walkthrough during both days. That means that practice report is an estimation, so Murphy's lack of participation shouldn't be taken too seriously. The rookie defensive tackle has been sidelined since Week 3. When healthy, Murphy figures to continue serving as a rotational player at defensive end and defensive tackle. He has six combined tackles, one tackle for loss, and 0.5 sacks across three games this season. The Seahawks used the 16th overall pick on Murphy during this year's draft, so they have high hopes for the young tackle. It remains to be seen if Murphy will be healthy enough to suit up for the Thursday night matchup against the San Francisco 49ers.

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The Denver Broncos have signed wide receiver A.T. Perry to their practice squad on Tuesday. The 24-year-old was recently released by the New Orleans Saints after spending his rookie campaign with them in 2023. The former sixth-round continued to be a healthy scratch on gameday, so the team eventually decided to move on. Perry hauled in 12 receptions for 246 yards and four touchdowns across 10 games with the Saints last season. He'll be extra depth for the Broncos right now, but could find his way to the active roster at some point. For now, fantasy managers can leave Perry on the waiver wire.

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Seattle Seahawks tight end Pharaoh Brown (groin) returned to practice as a full participant during Tuesday's session. The 30-year-old was a limited participant during Monday's walkthrough, but appears to be feeling better now. That is good news for Brown as the Seahawks head into a Thursday night matchup against the San Francisco 49ers. Brown has been quiet this season and had only one reception for seven yards last week. He figures to serve as depth with Noah Fant being the primary tight end and AJ Barner has started getting involved as well. Brown can be left on the waiver wire ahead of this Week 6 matchup.

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