Detroit Lions defensive end Marcus Davenport (groin) is officially inactive for Week 2 against the Tampa Bay Buccaneers. He was trending in the wrong direction after being listed as doubtful. The 28-year-old is coming off his debut with the team in which he registered half a sack. Look for James Houston and Josh Paschal to earn more opportunities in his absence.

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San Francisco 49ers safety Talanoa Hufanga (knee) is inactive for Week 2 versus the Minnesota Vikings. He had been listed as doubtful. Hufanga tore his ACL last season and has not yet appeared in a game in 2024. The 25-year-old had seven interceptions, two forced fumbles, and two sacks through 27 games between 2022 and 2023. George Odum will start in his place this week.

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Washington Commanders wide receiver Jamison Crowder (coach's decision) is a healthy scratch for Week 2 against the New York Giants. The veteran had logged just three snaps in the season opener, catching one pass for five yards. Fellow receiver Noah Brown will be active in Crowder's place. Brown had been a healthy scratch in Week 1 as he was still acclimating to the Commanders' offense. Even if this dynamic remains in place for weeks to come (Brown active, Crowder inactive), Brown isn't a reliable fantasy option.

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New Orleans Saints cornerback Marshon Lattimore (hamstring) is officially inactive for Week 2 versus the Dallas Cowboys. He had been listed as questionable but was trending in the wrong direction after not practicing on Friday. By Sunday morning, reports emerged indicating that the Saints wanted to be cautious with Lattimore and might hold him out. Indeed, he'll sit out. Lattimore had been slated to cover CeeDee Lamb on Sunday, so this development is great news for the Cowboys' WR1 and fantasy managers who have him on their rosters.

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New Orleans Saints wide receiver A.T. Perry (coach's decision) is a healthy scratch for Week 2 against the Dallas Cowboys. The 24-year-old missed Week 1 with a hand injury but was a full participant in practice this week. Now, he's sidelined again, but this time for non-injury reasons. The Saints will enter their second game of the season with Chris Olave and Rashid Shaheed atop their depth chart, followed by undrafted rookie Mason Tipton as their No. 3 receiver.

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Jaguars tight end Evan Engram has been ruled out for the Week 2 game. He suffered a hamstring injury in pregame warmups.

Cleveland Browns offensive tackle Jack Conklin (knee), who was considered questionable for the Week 2 tilt against the Jacksonville Jaguars on the road, has officially been ruled out for Sunday's game. With offensive tackle Jedrick Wills Jr. (knee) having already been ruled out earlier this week, Cleveland's offensive line will be missing some key pieces this weekend. The 30-year-old Conklin was limited in practice all of last week and also sat out the season-opening blowout loss to the Dallas Cowboys in which the Browns' offense looked like a disaster. With both Conklin and Wills out, expect James Hudson and Dawand Jones to see plenty of playing time on Sunday on the book ends of Cleveland's offensive line. This is more bad news for a Browns offense that has come under a lot of scrutiny already under quarterback Deshaun Watson.

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Detroit Lions wide receiver Jameson Williams (ankle) is officially active for Sunday's game against the Tampa Bay Buccaneers. He had been listed as questionable after practicing in a limited capacity on Friday, but as the weekend progressed, it became clear that he was healthy enough to suit up. Williams is looking to build off a huge Week 1 showing in which he led the team with five catches, 121 yards, and one touchdown. We need to see this type of production on a more consistent basis before ranking Williams as a must-start fantasy weapon, but he's certainly worth consideration in most leagues with 10 or more teams. If he can produce alongside Amon-Ra St. Brown and Sam LaPorta, he has league-winning upside. For Week 2, he should be deployed as a mid-to-high WR3 option.

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Philadelphia Eagles wide receiver A.J. Brown (hamstring) has been downgraded to out ahead of Monday Night Football versus the Atlanta Falcons. He had already been trending in the wrong direction after missing practice on Saturday, and now we get confirmation that he won't suit up on primetime television. Fantasy managers will appreciate the timing of this announcement as it gives them roughly one hour to find a replacement for Brown in their lineups before the Sunday 1 p.m. games kick off. The Eagles will move forward with DeVonta Smith as their No. 1 receiver on Monday with additional opportunities for Saquon Barkley and Dallas Goedert. Receivers Olamide Zaccheaus and Jahan Dotson should get more looks, too, but neither of them is even worth rostering in leagues with 14 teams or fewer.

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Jacksonville Jaguars tight end Evan Engram (hamstring) suffered a hamstring injury during pre-game warmups on Sunday and has been ruled out for Week 2 against the visiting Cleveland Browns. Fantasy managers that had Engram in their starting lineups for this weekend are going to have to adjust on the fly. In Jacksonville, Brenton Strange and Luke Farrell will now battle for targets in the passing game with Engram sidelined, but neither player is an acceptable starting replacement for Engram. The most likely scenario is that wide receivers Christian Kirk, rookie Brian Thomas Jr. and Gabe Davis will see more targets through the air against a tough Browns defense. The 30-year-old Engram had a rough season debut last week as well, catching only one of four targets for five yards in the loss to the Miami Dolphins. There's no guarantee he'll be able to play in Week 3 against the Buffalo Bills.

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Carolina Panthers running back Raheem Blackshear (personal) and tight end Tommy Tremble (hamstring, back) are both active for Week 2 against the Los Angeles Chargers. They had been listed as questionable entering the weekend. Blackshear was absent from practice this week for personal matters, but it appears he's good to go for Sunday's home game. Although he remains a depth option in Carolina's backfield, he offers plenty of value on special teams as the Panthers' primary kick returner. With the Panthers susceptible to surrendering plenty of scores, Blackshear could be busy returning kickoffs this season. He's only a worthwhile fantasy option in leagues that award points for return yards. Meanwhile, Tremble is suiting up after being limited on Friday. He was inactive in Week 1 and figures to poach snaps from rookie Ja'Tavion Sanders. Even without a clear top tight end in Carolina, there's no real path to fantasy relevance for Tremble.

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New Orleans Saints quarterback Derek Carr (illness) was ill on Sunday morning but will play against the Dallas Cowboys on Sunday, according to a note on NFL.com's official injury report tracker. Carr was added to the injury report Sunday but did not have any designation, which is a good sign that he won't have any limitations in Week 2. The quarterback faces a tough matchup in the form of the Dallas Cowboys, but he's coming off a big performance against the Panthers and figures to maintain some QB2 appeal this weekend. He's a fine option in deeper two-quarterback leagues.

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New England Patriots running back JaMycal Hasty (knee) is officially active on Sunday for the Week 2 game against the Seattle Seahawks, while wide receiver Kayshon Boutte is a healthy inactive. Hasty popped up on the team's injury report on Thursday after putting in a limited practice, but his knee injury wasn't serious enough to sideline him this weekend. The 28-year-old is well off the fantasy radar in the vast majority of fantasy leagues as the No. 3 RB behind Rhamondre Stevenson and Antonio Gibson in one of the weaker offenses in the NFL. In the surprising Week 1 win over the Cincinnati Bengals, Hasty had didn't touch the ball at all on offense. Boutte didn't play a single offensive snap last weekend and will now take a seat so that rookie Javon Baker can make his NFL debut after he was a healthy scratch in Week 1.

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The Indianapolis Colts have declared C Tanor Bortolini, WR Josh Downs, S Julian Blackmon, LB Genard Avery, OT Blake Freeland, TE Will Mallory and QB Sam Ehlinger inactive for Week 2.

From TheHuddle

Green Bay Packers running back MarShawn Lloyd (hamstring) is officially active for Sunday's game against the Indianapolis Colts. He had been listed as questionable but was trending in the right direction throughout the weekend. As Lloyd makes his NFL debut, he could steal some touches from backup Emanuel Wilson. Both backs are expected to touch the ball Sunday despite operating behind Josh Jacobs. In fact, Green Bay could have a heavy dependence on its rushing attack with Malik Willis starting in place of the injured Jordan Love (knee). If the Packers want to keep the clock ticking and reduce the chances of a Willis turnover, we could see a lot of opportunities for Jacobs with Lloyd and Wilson each getting at least a handful of touches, too. Still, Lloyd is not an appealing redraft option and can be left on the bench in most dynasty leagues, too.

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Green Bay Packers quarterback Jordan Love (knee) is officially inactive for Sunday's game against the Indianapolis Colts. Green Bay technically left the door open for him to play by listing him as doubtful, but it was always clear that he wasn't going to suit up. The talented, young quarterback injured his MCL late in the season opener against Philadelphia and is expected to miss roughly three games, giving him a Week 5 return date. Until then, Malik Willis will quarterback the Packers. He has yet to prove himself as a capable starting quarterback in the NFL, which means fantasy managers should temper expectations for the Packers and their playmakers, including Josh Jacobs, Jayden Reed, and Christian Watson.

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Los Angeles Chargers wide receiver Joshua Palmer (knee) is officially active for the Week 2 contest against the Carolina Panthers on the road on Sunday. Palmer was limited in practice on Wednesday and Thursday before being listed as a DNP on Friday, putting his status in question for the team's first road game of the season. However, the 24-year-old will be good to go and should continue to start alongside rookie Ladd McConkey and Quentin Johnston with DJ Chark (hip) on Injured Reserve. Palmer caught just two passes for 15 yards in the season-opening win over the Las Vegas Raiders and was ejected in the contest, making it a forgettable season debut. However, he did play 81% of the offensive snaps prior to his ejection, and he makes for a WR4/flex with upside against a Panthers defense that was torched by quarterback Derek Carr and the Saints in Week 1.

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The Detroit Lions have declared WR Isaiah Williams, DE Marcus Davenport, CB Ennis Rakestraw Jr., OT Giovanni Manu, LB Trevor Nowaske, OT Colby Sorsdal and CB Ifeatu Melifonwu inactive for Week 2.

From TheHuddle

The New Orleans Saints have declared WR A.T. Perry, CB Marshon Lattimore, LB D'Marco Jackson, TE Dallin Holker, QB Spencer Rattler, DL Khalen Saunders and LB Jaylan Ford inactive for Week 2.

From TheHuddle

Seattle Seahawks running back Kenneth Walker III (oblique) is officially inactive for Sunday's game against the New England Patriots. He had been listed as doubtful entering the weekend, so this latest update does not come as a surprise. The star running back will watch from the sidelines as Zach Charbonnet operates as the Seahawks' No. 1 running back. Charbonnet has some high-end RB3/FLEX appeal against a Patriots defense that did allow a rushing touchdown despite playing a strong game against the Cincinnati Bengals last week.

From RotoBaller