Los Angeles Chargers (7-4) at Atlanta Falcons (6-5), 1 p.m. ET, FOX

Atlanta holds a one-game lead over the Tampa Bay Buccaneers in the NFC South but lost the last two games. The Falcons are seeking their first winning season and playoff appearance since 2017. Prior to the bye last week, Atlanta lost 38-6 on the road to the Denver Broncos. The offense managed just 226 total yards, while producing its lowest point total of the season. The Falcons' defense didn't fare much better, as the unit was gashed by rookie quarterback Bo Nix, who threw four touchdowns. QB Kirk Cousins has thrown for 2,807 yards -- good for fifth in the NFL -- and would become the first Falcons quarterback since Matt Ryan in 2008 to lead the team to the playoffs in his first year. Chargers first-year head coach Jim Harbaugh has his team in the second AFC wild-card spot, sandwiched between the 8-4 Baltimore Ravens and 7-5 Broncos and gained more breathing room with Miami's loss at Green Bay on Thanksgiving night. After starting the year 3-3, the Chargers won four games in a row before dropping their home game Monday to the Ravens, 30-23. In a battle between Jim and his brother John, Los Angeles squandered a 10-0, second-quarter lead. Making matters worse, starting running back J.K. Dobbins suffered an MCL sprain in his left knee in the loss, and is expected to be out this week. He is considered week-to-week beyond that. Chargers backup running backs Gus Edwards and Hassan Haskins will try to account for the absence of Dobbins, who's rushed for 766 yards and eight touchdowns this season.

Pittsburgh Steelers (8-3) at Cincinnati Bengals (4-7), 1 p.m., CBS

Steelers coach Mike Tomlin heaped praise upon Bengals QB Joe Burrow for his MVP-level play in 2024 and warned his troops this road trip isn't one to take lightly. Pittsburgh isn't panicked after a surprising Thursday night loss at Cleveland last week and with 10 days between games, Tomlin expects an effort representative of a division leader on Sunday. All three of the Steelers' losses this season have come against teams that currently have a losing record. Pittsburgh also fell to the Dallas Cowboys and Indianapolis Colts. The Bengals have been in a rut -- with three losses in their past four games -- and were on the wrong end of a 34-27 decision against the Chargers on Nov. 17. Like Pittsburgh, Cincinnati came back from a sizable deficit only to lose the last time out. Joe Burrow threw three second-half touchdown passes against Los Angeles as the Bengals climbed out of a 27-6 hole, but Chargers running back J.K. Dobbins found the end zone from 29 yards out with 18 seconds left in regulation to break a 27-27 tie. Burrow went 28-for-50 passing for 356 yards and the three TDs. Making things harder for the Steelers could be the absence of linebacker Alex Highsmith, who did not practice on Wednesday because of an ankle injury that has forced him to miss two games.

Houston Texans (7-5) at Jacksonville Jaguars (2-9), 1 p.m., FOX

A week after a demoralizing loss to the Tennessee Titans, the AFC South-leading Texans visit Jacksonville with the Jaguars rested following a bye week. The week prior, Jacksonville was overwhelmed in a humiliating 52-6 loss to the Detroit Lions. It marked the fourth straight setback for the Jaguars, who had dropped their previous three games by a combined 13 points. Jaguars coach Doug Pederson noted that changes are coming, although he opted not to show his cards. QB Trevor Lawrence, who has not played since Nov. 3 due to a left shoulder injury, is eager to play and compete against Texans QB C.J. Stroud, who has run into some struggles during his sophomore season. Stroud has thrown nine interceptions in 12 games (all starts) after throwing only five as a rookie. He was picked off twice in the 32-27 setback against Tennessee, also throwing for 247 yards and two touchdowns on 20-for-33 passing. The Texans have lost three of their past four games and four of their past six as defenses continue to solve Stroud. The Texans topped Jacksonville 24-20 back on Sept. 29.

Arizona Cardinals (6-5) at Minnesota Vikings (9-2), 1 p.m., FOX

Add the Minnesota Vikings to the observers who were urging the Bears to use a time out in the final 25 seconds of their Thanksgiving Day loss to the Lions, who maintained a one-game lead in the NFC North by hanging on for a 23-20 win. With their focus back on the field, the Vikings are targeting a second five-game winning streak this season when the Cardinals come to town. Minnesota claimed a 30-27 overtime win on the road against the Bears last Sunday. The Vikings have won each of their past three games on the road, and they return home for the first time since beating the Indianapolis Colts 21-13 four weeks ago. Arizona is trying to return to winning after a 16-6 defeat on the road against the Seattle Seahawks last week. The defeat snapped a four-game winning streak for the Cardinals, who started the season 2-4 but have gone 4-1 since then. But Sunday's game and a rematch against Seattle could prove pivotal for his team's postseason hopes. Two wins would put Arizona at 8-5; two losses put the team below .500. Kyler Murray owns a 98.0 passer rating, throwing for 2,343 yards, 12 touchdowns and four interceptions. He also has 380 yards and four touchdowns on the ground. James Conner is Arizona's top backfield threat with 705 rushing yards and five touchdowns. Tight end Trey McBride has a team-high 61 catches for 685 yards.

Indianapolis Colts (5-7) at New England Patriots (3-9), 1 p.m., CBS

Penalties crippled the Colts' offense and erased multiple big plays by QB Anthony Richardson in Week 12, a loss to the Lions that left the locker room frustrated. But all is not lost for the Colts as they hit the road for another AFC East opponent. Richardson and Co. collected only 11 first downs in a 24-6 loss to the Detroit Lions. Richardson completed 11 of 28 passes for 172 yards. He was also the Colts' leading rusher (10 carries, 61 yards). Star running back Jonathan Taylor was held to 35 yards on 11 carries against Detroit, but Indianapolis coach Shane Steichen is hopeful that he will do more damage against the Patriots. Getting the run going could become even more important if wide receivers Josh Downs, Alec Pierce and Ashton Dulin aren't able to take the field. All three wouldn't have practiced on Wednesday had the Colts not opted to simply do a walkthrough. Downs' absence could end up hurting Indianapolis the most. The second-year man has a team-leading 53 catches for 594 yards and four TDs. Patriots rookie QB Drake Maye said he's not worried about the so-called wall first-year players often encounter with the longer NFL season. Maye makes his ninth appearance (eighth start) of the campaign. He didn't excel in the Patriots' 34-15 loss to the Miami Dolphins last Sunday. He finished with 222 yards, one touchdown and one interception on 22-of-37 passing.

Seattle Seahawks (6-5) at New York Jets (3-8), 1 p.m. ET, FOX

Most of the focus for the Jets, who have lost six of their past seven games, already points to next season. That's part of the reason they might not risk a hobbled Breece Hall, who has 632 yards rushing along with 46 catches for 401 yards and six total touchdowns this season but began the week with a knee injury coming out of the bye week. QB Aaron Rodgers, who turns 41 Monday, wasn't among those listed on the injury report for the first time since September. The streaky Seahawks are back to their winning ways and are tied with the Cardinals atop the NFC West. After opening the season by going 3-0, Seattle lost five of its next six games before winning its past two against division rivals. Coach Mike Macdonald's defense has been much improved since a bye in Week 10, as the Seahawks defeated the host San Francisco 49ers 20-17 and visiting Arizona 16-6 over the past two weeks. Coby Bryant returned an interception 69 yards for a touchdown and Leonard Williams had 2.5 sacks against the Cardinals.

Tennessee Titans (3-8) at Washington Commanders (7-5), 1 p.m. ET, CBS

Trade deadline acquisition Marshon Lattimore, a physical cornerback picked up from the Saints, could debut for the Commanders. They could use a jolt. Having lost three straight after a 7-2 start, the Commanders last won Nov. 3 on Hail Mary touchdown from rookie QB Jayden Daniels. Tennessee is coming off a 33-27 upset of the Houston Texans that featured one of Will Levis' best starts of the season. Washington has lost to the Pittsburgh Steelers, Philadelphia Eagles and Dallas Cowboys the past three weeks and enters Week 13 two games behind the NFC East-leading Eagles. After sputtering for three quarters against Dallas, Washington scored 17 fourth-quarter points in a wild 34-26 loss last week. Daniels completed 25 of 38 passes for 274 yards, two touchdowns and two interceptions, but 86 of those yards came on a late catch-and-run score by Terry McLaurin. In the three recent losses, Daniels has a 61.5 completion percentage, three touchdowns, three interceptions and a 77.7 passer rating while being sacked 10 times. Daniels did have his best rushing day since Week 1 when he gained 74 yards against Dallas. Improvement might not come easy. The Titans' defense that ranks second in the NFL behind the Eagles, giving up just 276.4 yards per game. Levis returned from his right shoulder injury and the Titans have averaged 224.3 passing yards per game, with nine touchdown passes and six interceptions in the past six outings. RB Tony Pollard had his best game of the season against Houston, rushing 24 times for 119 yards and a touchdown.

Tampa Bay Buccaneers (5-6) at Carolina Panthers (3-8), 4:05 p.m. ET, FOX

Few introductions are needed on Sunday, as first-year Panthers coach Dave Canales came to Carolina after serving as Buccaneers offensive coordinator a season ago. Canales' prized pupil last season, Tampa Bay quarterback Baker Mayfield was with the Panthers for part of the 2022 campaign. The Buccaneers (5-6) playing a division opponent for the first time since an Oct. 27 loss to the Atlanta Falcons. The goal will be notching back-to-back wins for the first time since the first two weeks of the season. Four different ball-carriers, including Mayfield, found the end zone on the ground during a 30-7 drubbing of the New York Giants last Sunday. Mayfield also completed 24 of 30 passes for 294 yards. Star wideout Mike Evans was back in action for Tampa Bay following a three-game absence due to a hamstring injury. He finished with five receptions for 68 yards against the Giants and now gets a crack at a Carolina team allowing a league-high 30.9 points per game this season. However, the Panthers have tightened up their play as of late, winning two games in a row before hanging with the two-time defending champion Kansas City Chiefs in a 30-27 setback last Sunday. The outing against Kansas City may have been the most efficient performance of Panthers quarterback Bryce Young's two-year career. Young completed 21 of 35 passes for 263 yards and one score without throwing a pick. Carolina and Tampa Bay might as well get used to each other, as the two teams will collide again in four weeks.

Los Angeles Rams (5-6) at New Orleans Saints (4-7), 4:05 p.m. ET, FOX

The Saints won both games they have played since interim head coach Darren Rizzi was promoted from special teams coordinator to replace Dennis Allen, who was fired Nov. 4 after a seven-game losing streak. New Orleans comes out of its bye sitting in third place in the NFC South, two games behind the Falcons and one game behind the Buccaneers. The Rams' visit will be the third straight home game for Rizzi as interim head coach. The Saints beat the Falcons 20-17 in his debut and followed that with a 35-14 victory over Cleveland in which they outscored the Browns 21-0 in the fourth quarter. A series of significant injuries contributed to the losing streak, but New Orleans has gotten progressively healthier in recent weeks. Quarterback Derek Carr improved in each of the last three contests after returning from a three-game absence caused by an oblique strain. The return of center Erik McCoy from groin surgery after a seven-game absence was a boost against the Browns. The Saints' signing of veteran receiver Marquez Valdes-Scantling on Oct. 22 with top receivers Chris Olave and Rashid Shaheed injured has given Carr a much-needed big-play threat. In the past two games, Valdes-Scantling has three touchdown receptions and has averaged 39.2 yards on five catches. The Rams are coming off a 37-20 home loss against the Eagles on Sunday night, their second defeat in three games after a three-game winning streak. They are tied with the San Francisco 49ers for last place in the NFC West, but they're just one game behind the first-place Seahawks and Cardinals and have one game remaining against each of the three rivals. Coach Sean McVay called the loss to the Eagles "a humbling night" after his team struggled on both sides of the ball. The defense allowed Saquon Barkley to rush for a career-high and franchise-record 255 yards as well as two touchdowns, and Los Angeles quarterback Matthew Stafford was sacked five times.

Philadelphia Eagles (9-2) at Baltimore Ravens (8-4), 4:25 p.m. ET, CBS

The Eagles have won seven in a row and play four of their final six games in Philadelphia, traveling only about 125 miles to visit the Ravens this weekend and the Commanders in Week 16. Sunday's game features the NFL's two leading rushers. Saquon Barkley (1,392 yards) and Derrick Henry (1,325) are far ahead of Green Bay's Josh Jacobs (944) in third place. Henry leads the league with 13 rushing touchdowns. Barkley (10) is tied for fourth and Philadelphia quarterback Jalen Hurts (11) tied for second. The matchup also features two of the top candidates for Most Valuable Player honors entering Week 13 in Barkley and Baltimore quarterback Lamar Jackson, who won his second MVP award last season. Their competition includes quarterbacks Josh Allen of Buffalo and Jared Goff of Detroit, with Allen widely considered the favorite. The showdown at M&T Bank Stadium also pits Baltimore's No. 1 offense (426.7 yards per game) and No. 2 scoring offense (30.3 points per game) against Philadelphia's No. 1 defense (274.6) and No. 6 scoring defense (18.1). The Eagles have held seven consecutive opponents to under 300 total yards, while the Ravens have gained at least 329 yards of offense in all 11 games. Philadelphia is coming off a 37-20 road win over the Los Angeles Rams on Sunday night in which Barkley smashed the franchise record with 255 rushing yards. Baltimore also earned a prime-time win in Los Angeles last week, defeating the Chargers 30-23 in the "Harbaugh Bowl" on Monday night behind Jackson's three touchdowns (two passing, one rushing). Philadelphia is 5-1 away from home this season -- 6-1 if you count their season-opening "home" victory against the Packers in Sao Paulo, Brazil. Baltimore is 4-1 at home.

San Francisco 49ers (5-6) at Buffalo Bills (9-2), 8:20 p.m. ET, NBC

Buffalo can clinch the AFC East before the calendar flips to December while the 49ers are staggered and stumble into New York bracing for snow with a good chance of backups in the forecast. QB Brock Purdy (shoulder) missed the Week 12 loss at Green Bay and San Francisco was also without All-Pro DE Nick Bosa (oblique, hip), with LT Trent Williams (ankle) motoring through the locker room this week on a knee scooter. Buffalo is not the ideal place to try to get healthy. The Bills dealt the Chiefs their only loss this season and Buffalo has scored at least 30 points in five consecutive games. QB Josh Allen has passed for 18 touchdowns against five interceptions this season after throwing a career-worst 18 picks last season. San Francisco got walloped last week without Purdy, falling 38-10 to the host Packers. Brandon Allen started at quarterback and completed 17 of 29 passes for 199 yards with one touchdown pass, one interception and one lost fumble. Allen is 2-8 as an NFL starter. He is again getting heavy work in practice in case Purdy's shoulder doesn't significantly improve. The 49ers could use a big performance from running back Christian McCaffrey, who had just 31 yards on 11 carries and caught three passes for 37 yards against Green Bay.