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49ers coach: All-Pro OT Trent Williams (ankle) likely to miss rest of season

Wed Dec 18 5:13pm ET
Field Level Media

All-Pro left tackle Trent Williams, who has missed the last four San Francisco games because of an ankle injury, is likely done for the season, 49ers coach Kyle Shanahan said Wednesday.

"I mean, if he gets back to healthy, we'd play him," Shanahan said. "But it's not like that right now, so it's getting closer to being that way."

San Francisco (6-8) has regular-season games remaining at Miami on Sunday, at home against Detroit on Dec. 30 and at Arizona on a day to be determined.

Williams, 36, has not played since the 20-17 home loss to the Seattle Seahawks on Nov. 17. He has started all 10 games he has played this season and played 98 percent (649) of the offensive snaps in those games.

Jaylon Moore has stepped in for Williams, who was not expected to practice on Wednesday. Moore, 26, was a fifth-round pick of the 49ers in the 2021 NFL Draft out of Western Michigan.

Williams is an 11-time Pro Bowl selection (2012-18, 2020-23) and three-time first-team All-Pro (2021-23). Washington selected him fourth overall in the 2010 draft out of Oklahoma.

Shanahan also said Wednesday that rookie running back Isaac Guerendo, who sustained a hamstring injury in the loss last Sunday to the Los Angeles Rams, will not practice.

Linebacker Dre Greenlaw, who returned to action last week from an Achilles injury in last season's Super Bowl, will be limited at practice, Shanahan said. Greenlaw left the game against the Rams in the third quarter with soreness in that area and his knee. All-Pro defensive end Nick Bosa (hip/oblique) also will be a limited participant.

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Player Notes
Tua Tagovailoa Dec 18 6:00pm CT
Tua Tagovailoa

Miami Dolphins quarterback Tua Tagovailoa (hip) was limited in Wednesday's practice due to a hip injury. It's a new injury for Tagovailoa, but the fact that he's practicing at all in the first session of the week is a sign the injury likely isn't serious enough to keep him from playing in Week 16 versus the visiting San Francisco 49ers. As long as the 26-year-old signal-caller is able to return to a full practice in the next two days, he should be removed from the final injury report by Friday. Tagovailoa should probably be considered a high-end QB2, at best, with limited upside in Week 16 despite clearing 300 passing yards in three previous games before the Week 15 loss to the Houston Texans, where he went for 196 yards, one touchdown and three interceptions. The 49ers defense has been one of the worst matchups in fantasy for opposing QBs, especially in the last five weeks.

From RotoBaller

Jakobi Meyers Dec 18 6:00pm CT
Jakobi Meyers

Las Vegas Raiders wide receiver Jakobi Meyers (ankle) remains on the Week 16 injury report and was listed as limited in Wednesday's practice. Meyers also had his practice reps limited a bit last week due to his ankle injury, but he was eventually cleared and played in the Week 15 loss to the Atlanta Falcons on Monday night. The 28-year-old pass-catcher caught five of his nine targets in that game for 59 yards in quarterback Desmond Ridder's first start of the year. He should be fine to play this weekend in an excellent matchup against the poor Jacksonville Jaguars secondary, making him intriguing in starting fantasy lineups for semifinal matchups in most leagues. Additionally, it looks like quarterback Aidan O'Connell (knee) will return from a one-game absence, which definitely will give Meyers more upside as the WR1 in Vegas.

From RotoBaller

DeVonta Smith Dec 18 5:50pm CT
DeVonta Smith

Philadelphia Eagles wide receiver DeVonta Smith (back) was rested in the first practice of the week on Wednesday while managing a back injury. Smith missed Weeks 12 and 13 due to a hamstring injury, but now he's managing a minor back injury that shouldn't put him in danger of missing Week 16 against the division-rival Washington Commanders. In two games since Smith returned from his hamstring injury, he's found the end zone twice and has caught 15 of 18 targets for 146 yards. The 26-year-old went off for 11 catches on 12 targets for 109 yards and a score in last week's win over the Pittsburgh Steelers. It was the first time he had gone over seven targets since Week 3, but Philly could emphasize their passing attack down the stretch heading into a positive matchup against Washington. Smith will be on the WR2/3 borderline in Week 16 in fantasy.

From RotoBaller

A.J. Brown Dec 18 5:40pm CT
A.J. Brown

Philadelphia Eagles wide receiver A.J. Brown was rested during Wednesday's practice and wasn't listed with an injury designation on the first report of Week 16. It's a good sign for Brown after he got up slow after a tackle late in the Week 15 win over the Pittsburgh Steelers. The Eagles greased the squeaky wheel with Brown and the passing attack last weekend, with Brown catching a season-high eight passes on 11 targets for 110 yards and a touchdown. Look for the Eagles to try and continue to keep their passing onslaught going this weekend against the division-rival Washington Commanders on Sunday. If the Eagles continue to feed Brown the ball through the air, he'll have a good chance to improve on his five catches for 65 yards that he had in the first meeting against Washington on Nov. 14. Brown will be active in Week 16 and will have clear WR1 upside. Start him.

From RotoBaller

Larry Ogunjobi Dec 18 5:30pm CT
Larry Ogunjobi

Pittsburgh Steelers linebacker T.J. Watt (ankle) was upgraded to a limited practice participant on Wednesday after he didn't practice on Tuesday. Meanwhile, safety DeShon Elliott (hamstring) and cornerback Donte Jackson (back) didn't practice, while defensive tackle Larry Ogunjobi (groin) was limited. Watt suffered a low-ankle sprain late in the Week 15 loss to the Philadelphia Eagles, but the Steelers have been hopeful that he can play in a big divisional clash on Saturday against the Baltimore Ravens. The 30-year-old's ability to return to practice on Wednesday is a sign he's trending in the right direction, although another upgrade to a full-go on Thursday would be ideal. Fantasy managers should be fading Pittsburgh's defense in fantasy against a high-scoring Ravens offense this weekend, but especially if Watt is unable to play. He's a must-start in IDP formats if he's active on Saturday.

From RotoBaller

CeeDee Lamb Dec 18 5:20pm CT
CeeDee Lamb

Dallas Cowboys wide receiver CeeDee Lamb (shoulder) continues to battle through a shoulder injury and was limited in Wednesday's practice session. Lamb suffered an AC joint sprain in his shoulder back in Week 9 and has been managing the issue ever since, although he has not missed any time because of it. The 25-year-old's fantasy stock took a hit when quarterback Dak Prescott (hamstring) was lost for the year, but he's still been playable on a weekly basis in fantasy lineups. Since injuring his shoulder, Lamb also has 41 receptions on 60 targets for 429 receiving yards and two touchdowns. It speaks to Lamb's abilities on the football field that he remains a must-start wideout with WR1 upside in fantasy with Cooper Rush under center. Lamb should play on Sunday night and will have considerable upside against a vulnerable Bucs secondary.

From RotoBaller

Baker Mayfield Dec 18 5:10pm CT
Baker Mayfield

The Tampa Bay Buccaneers listed quarterback Baker Mayfield (knee) as a non-participant in the first practice of the week on Wednesday due to a knee injury. It's unclear as of right now if Mayfield's knee injury is serious enough to keep him out of Week 16 against the Dallas Cowboys on Sunday night or if the Bucs are just giving the veteran QB some extra rest late in the season. The 29-year-old went off in a very tough matchup in the Week 15 win over the Los Angeles Chargers, going 22-for-27 for 288 yards, four touchdowns and one interception. Mayfield has a career-high 32 touchdown passes in 2024, and barring a late-season injury, he will surpass 4,000 passing yards for a second straight season. Keep an eye on Mayfield's practice status the rest of the week, but if he's available, he'll be a solid midrange QB1 for fantasy against a beatable Dallas defense.

From RotoBaller

Marquise Brown Dec 18 5:10pm CT
Marquise Brown

Kansas City Chiefs wide receiver Marquise Brown (shoulder) put in another day of full practice on Wednesday and looks well on his way to making his team debut on Saturday in Week 16 against the Houston Texans. Hollywood injured his left shoulder in the preseason and required surgery, causing him to miss his entire first season in KC until now. Brown has made great progress of late and could be activated from Injured Reserve by Friday in order to play on Saturday, but it's not a lock. And for fantasy purposes, if Brown is active, he won't be a recommended starter in fantasy lineups with trips to the fantasy championship next weekend on the line in most leagues. The Chiefs are fully expected to ease Brown back into the offense to close out the regular season so that he can potentially take on a bigger role in the postseason.

From RotoBaller

Justice Hill Dec 18 5:00pm CT
Justice Hill

Baltimore Ravens running back Justice Hill (personal) missed the team's practice on Wednesday due to personal reasons. The Ravens still have one more day of practice this week on Thursday before heading into a big Week 16 divisional clash against the Pittsburgh Steelers on Saturday. The 27-year-old Hill should be back with the team before then and will look to continue his role as mainly a pass-catching change-of-pace option behind backfield leader Derrick Henry. Hill only has 198 rushing yards and one rushing score on 45 carries over 14 games in 2024, but he's added a career-high 42 catches on 50 targets for 383 yards and three more TDs. He's caught nine passes for 76 yards and a touchdown the last two weeks. Hill is a volatile fantasy asset because of his lack of volume behind King Henry, but fantasy managers could do worse with a flex option in deep PPR leagues.

From RotoBaller

Nelson Agholor Dec 18 4:50pm CT
Nelson Agholor

Baltimore Ravens wide receiver Nelson Agholor (concussion) remains in the league's concussion protocol and missed his second straight day of practice this week on Wednesday. Agholor suffered a concussion in the Week 15 win over the New York Giants and is now looking unlikely to play on a quick turnaround this Saturday against the division-rival Pittsburgh Steelers. Rashod Bateman (foot) also popped up on this week's injury report on Wednesday, so Baltimore's receiving corps is a little banged up heading into a crucial Week 16 divisional battle. If both Agholor and Bateman are out, expected to see more of Tylan Wallace and Devontez Walker in three-wide sets with Zay Flowers. Agholor, 31, has only 14 receptions (29 targets) for 231 yards and two touchdowns in 14 games this year and wouldn't be in consideration for a lineup spot in fantasy if he was healthy.

From RotoBaller

Joe Mixon Dec 18 4:43pm CT
Joe Mixon

Houston Texans RB Joe Mixon (ankle) was limited during practice Wednesday, Dec. 18.

Fantasy Spin: Mixon should be on track to play against the Kansas City Chiefs as long as he does not suffer a setback before the game. He did not have a lot of success last week but should see a good amount of touches this week. He should be a starting option in all fantasy leagues.

From TheHuddle

Rashod Bateman Dec 18 4:40pm CT
Rashod Bateman

Baltimore Ravens wide receiver Rashod Bateman (foot) was added to Thursday's Week 16 injury report after putting in a limited practice. Bateman could now be up in the air to play on a short week this Saturday against the division-rival Pittsburgh Steelers, but we'll have a better idea of his status when the Ravens release their final injury report for the week on Thursday. The 25-year-old is having the best season of his career and is coming off a three-catch, 80-yard, two-touchdown performance in the Week 15 win over the New York Giants. With Nelson Agholor (concussion) looking unlikely to play this weekend, Bateman's status is more important for the Ravens. If he were to be inactive, Tylan Wallace and Devontez Walker would be thrust into starting roles alongside Zay Flowers. Bateman will be a touchdown-dependent WR4/flex, if active, in a tough matchup against Pittsburgh.

From RotoBaller

Hayden Hurst Dec 18 4:33pm CT
Hayden Hurst

Los Angeles Chargers TE Will Dissly (shoulder) and CB Cam Hart (concussion) did not participate in practice Wednesday, Dec. 18, and have been ruled out for Week 16. CB Elijah Molden (knee) did not practice and is listed as doubtful. DT Otito Ogbonnia (pelvis) was limited during practice and is listed as questionable. TE Hayden Hurst (hip), OG Zion Johnson (ankle) and LB Denzel Perryman (groin) fully participated in practice but are listed as questionable. CB Kristian Fulton (knee) fully participated in practice and is not on the injury report. The Chargers did not hold a practice Wednesday, so the practice report is an estimation.

From TheHuddle

Michael Pittman Jr. Dec 18 4:30pm CT
Michael Pittman Jr.

Indianapolis Colts wide receivers Michael Pittman Jr. (back) and Ashton Dulin (ankle) both missed the first practice of Week 16 preparation on Wednesday. In addition, Alec Pierce (concussion) also did not practice, so Indy's receiving corps is a bit beat up heading into Sunday's game against the division-rival Tennessee Titans. Pittman has been battling through a back issue of late but hasn't missed a game because of it, and he played 96 percent of the offensive snaps in the Week 15 loss to the Denver Broncos on Sunday. Our guess is the Colts are just resting the veteran wideout before he returns to practice later this week and plays on Sunday. The 27-year-old former second-rounder has become more of a hard-to-trust WR4/flex in the Colts' low-volume passing attack with young quarterback Anthony Richardson struggling with his accuracy. Pittman does have at least five catches and seven targets in the last four games, though.

From RotoBaller

Matt Gay Dec 18 4:30pm CT
Matt Gay

Indianapolis Colts kicker Matt Gay (neck) didn't take part in the team's first practice of the week on Wednesday. Gay is dealing with a neck injury coming out of the Week 15 loss to the Denver Broncos on Sunday in which he made both of his field-goal attempts and his lone extra-point opportunity. He still has two more days to get back on the practice field before the team takes on the division-rival Tennessee Titans in Week 16. We'll have a better idea on Gay's availability for the weekend based on whether the Colts make any moves to give them kicking insurance in case Gay can't kick on Sunday. The 30-year-old booter has made 88.9 percent of his field goals (24-for-27) this year while going a perfect 23-for-23 on extra points in 13 games in his second season with the team. Especially with his availability in question, fantasy managers should be looking at other kicking options in Week 16.

From RotoBaller

D.J. Jones Dec 18 4:23pm CT
D.J. Jones

Denver Broncos CB Riley Moss (knee) was limited during practice Wednesday, Dec. 18, but has been ruled out for Week 16. DE John Franklin-Myers (foot), DT D.J. Jones (finger) and CB Patrick Surtain II (ankle) fully participated in practice and are not on the injury report. The Broncos did not hold a practice Wednesday, so the practice report is an estimation.

From TheHuddle

Joe Mixon Dec 18 4:20pm CT
Joe Mixon

Houston Texans running back Joe Mixon (ankle) had his reps limited in practice for the second straight day on Wednesday in advance of the team's Week 16 contest on Saturday against the Kansas City Chiefs. Mixon tweaked his ankle in the Week 15 win over the Miami Dolphins, but head coach DeMeco Ryans said the 28-year-old back came out of the game fine and that he would be fine to face the Chiefs on a short week. However, Mixon might need a full practice session on Thursday to avoid a questionable tag. With a tough matchup against the Chiefs stingy defense upcoming and when considering Mixon's downturn in recent weeks, it may be best to consider him more of an RB2 rather than an RB1 in fantasy in Week 16. After finding the end zone at least once on the ground from Weeks 6-11, Mixon has averaged only 3.1 yards per carry with one TD in his last three contests.

From RotoBaller

Amon-Ra St. Brown Dec 18 4:13pm CT
Amon-Ra St. Brown

Detroit Lions WR Amon-Ra St. Brown (non-injury) did not participate in practice Wednesday, Dec. 18.

Fantasy Spin: St. Brown should return to practice later in the week and will see his normal workload in Week 16. He is coming off his next game of the season and will continue to be a significant part of the passing game. He should be a starting option in all leagues.

From TheHuddle

Za'Darius Smith Dec 18 4:13pm CT
Za'Darius Smith

Detroit Lions S Brian Branch (calf), OT Taylor Decker (non-injury), OG Graham Glasgow (knee), RB David Montgomery (knee), C Frank Ragnow (non-injury), DT D.J. Reader (non-injury), DE Za'Darius Smith (non-injury) and OG Kevin Zeitler (non-injury) did not participate in practice Wednesday, Dec. 18. S Ifeatu Melifonwu (hand) and LB Trevor Nowaske (concussion) fully participated in practice.

From TheHuddle

Joe Burrow Dec 18 4:10pm CT
Joe Burrow

Cincinnati Bengals quarterback Joe Burrow (knee, wrist) was listed as limited for the team's first practice of the week on Wednesday. Burrow has been managing a sore knee and has been getting treatment for his surgically repaired right wrist in the last week, but he was able to start in the Week 15 win over the Tennessee Titans and continued to be impressive, throwing for 271 yards and three touchdowns, although he also uncorked two interceptions and lost a fumble. There's no reason for fantasy managers not to expect the 28-year-old to be out there for a divisional matchup this Sunday against the Cleveland Browns. The Bengals are likely to miss the postseason, but hasn't been for lack of Burrow's effort as one of the best QBs in football in 2024. Even though he had only 181 yards and two TDs in the first meeting against Cleveland on Oct. 20, Burrow should be a top-five fantasy QB in Week 16.

From RotoBaller