Guest of the League
| Away | Home | Time | Away Probable | Home Probable | Status | |||
|---|---|---|---|---|---|---|---|---|
 | Pirates | at |  | Reds | 11:40am CT | Ashcraft (4-4) | Lodolo L (9-8) | |
 | Rays | at |  | Orioles | 12:05pm CT | Rasmussen R (10-5) | Povich L (3-8) | |
 | Twins | at |  | Rangers | 1:35pm CT | Ober R (5-9) | Mahle R (6-3) | |
 | Astros | at |  | Athletics | 2:35pm CT | Valdez L (12-11) | Ginn R (4-6) | |
 | Dodgers | at |  | Diamondbacks | 2:40pm CT | Yamamoto R (11-8) | Beeks L (5-2) | |
 | Marlins | at |  | Phillies | 5:05pm CT | Junk R (6-3) | Buehler R (9-7) | 5:05pm |
 | Tigers | at |  | Guardians | 5:40pm CT | Melton R (3-2) | Messick L (3-0) | 5:40pm |
 | White Sox | at |  | Yankees | 6:05pm CT | Martin R (7-10) | Rodon L (17-9) | 6:05pm |
 | Red Sox | at |  | Blue Jays | 6:07pm CT | Bello R (11-8) | Varland R (4-3) | 6:07pm |
 | Mets | at |  | Cubs | 6:40pm CT | McLean R (4-1) | Imanaga L (9-7) | 6:40pm |
 | Royals | at |  | Angels | 8:38pm CT | Lorenzen R (6-11) | Farris (1-2) | 8:38pm |
 | Rockies | at |  | Mariners | 8:40pm CT | Blalock R (2-5) | Woo R (15-7) | 8:40pm |
