Guest of the League
| Away | Home | Time | Away Probable | Home Probable | Status | |||
|---|---|---|---|---|---|---|---|---|
 | Rangers | at |  | Reds | 12:40pm ET | Leiter R (2-0) | Greene R (0-1) | |
 | Pirates | at |  | Rays | 1:10pm ET | Skenes R (1-0) | Pepiot R (0-1) | |
 | Royals | at |  | Brewers | 1:10pm ET | Ragans L (0-0) | Peralta R (0-1) | |
 | Angels | at |  | Cardinals | 1:15pm ET | Kikuchi L (0-1) | Gray R (1-0) | |
 | Twins | at |  | White Sox | 2:10pm ET | Lopez R (0-1) | Burke R (1-0) | |
 | Nationals | at |  | Blue Jays | 3:07pm ET | Gore L (0-0) | Lucas (0-0) | |
 | Cubs | at |  | Athletics | 3:35pm ET | Taillon R (0-1) | Springs L (1-0) | |
 | Giants | at |  | Astros | 4:10pm ET | Roupp R (0-0) | Valdez L (1-0) | |
 | Tigers | at |  | Mariners | 4:10pm ET | Skubal L (0-1) | Castillo R (0-1) | |
 | Guardians | at |  | Padres | 4:10pm ET | Lively R (0-0) | Cease R (0-0) | |
 | Mets | at |  | Marlins | 4:40pm ET | Holmes R (0-1) | Gillispie R (0-1) | |
 | Red Sox | at |  | Orioles | 6:35pm ET | Crochet L (0-0) | Eflin R (1-0) | 6:35pm |
 | Rockies | at |  | Phillies | 6:45pm ET | Freeland L (0-0) | Wheeler R (0-0) | 6:45pm |
 | Diamondbacks | at |  | Yankees | 7:05pm ET | Gallen R (0-1) | Rodon L (1-0) | 7:05pm |
 | Braves | at |  | Dodgers | 8:38pm ET | Elder R (0-0) | Snell L (1-0) | 8:38pm |
