Washington Commanders quarterback Jayden Daniels (knee) will start on Sunday against the hosting Los Angeles Chargers in Week 5, according to Nicki Jhabvala of The Washington Post. Daniels will wear the same brace on his knee that he had on Friday. The second-year signal-caller missed the last two games after spraining his left knee in Week 2. Veteran Marcus Mariota will head back to the bench after going 1-1 as Daniels' replacement. The Commanders' offense will get a boost with the return of Daniels, but he could be limited with his movement outside the pocket, and the matchup isn't ideal on the road against a ball-hawking defense. On top of that, Daniels will be without top receiver Terry McLaurin (quadriceps), who could miss additional time. Still, Daniels' dual-threat abilities at the position put him in the midrange QB1 category in fantasy in his return to the field.

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Washington Commanders head coach Dan Quinn said that wide receiver Deebo Samuel Sr. (heel) will play on Sunday in a Week 5 meeting with the hosting Los Angeles Chargers at SoFi Stadium, according to Tashan Reed of The Athletic. Samuel was looking questionable for this weekend after not practicing on Wednesday or Thursday, but he returned to a full practice on Friday and will be good to go to play on Sunday. Meanwhile, both Terry McLaurin (quadriceps) and Noah Brown (groin, knee) were ruled out for the second straight game, leaving Samuel as the team's top receiver yet again. The 29-year-old caught all six of his targets for 72 yards and his second touchdown of the season in last week's loss to the Atlanta Falcons, adding three carries for nine yards. Although the Chargers' defense is a strong unit, Samuel should have enough volume to be a must-start in all fantasy lineups, especially with quarterback Jayden Daniels (knee) returning.

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The Dallas Cowboys have ruled out wide receiver/return man KaVontae Turpin (foot) for their Week 5 matchup against the hosting New York Jets on Sunday, according to NFL Network's Tom Pelisser. In addition to Turpin, top receiver CeeDee Lamb will miss a second straight game with a high-ankle sprain he suffered in Week 3. Turpin suffered a foot sprain in Sunday night's tie with the Green Bay Packers and was unable to practice all week. With both Lamb and Turpin sidelined this weekend, Jalen Tolbert and Ryan Flournoy should be added to starting three-wide sets alongside George Pickens, who had 100-plus yards and two touchdowns as the WR1 for Dallas against Green Bay. Turpin is most valuable to the Cowboys for his return skills on special teams, but he had also been seeing a bigger role as the WR3 before Lamb's injury. His next chance to return will be in Week 6 against the Carolina Panthers.

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Detroit Lions wide receiver Kalif Raymond made his biggest play of the season on special teams in Week 4, returning a punt 65 yards for a touchdown against the Cleveland Browns. Raymond's work as a receiver has been much more subdued, as he has recorded just six catches for 47 yards on nine targets through four games. The Lions' passing game has a favorable matchup on paper in Week 5 against the Cincinnati Bengals, but Raymond is likely to remain in a limited role on offense. The 31-year-old is buried on the pecking order for targets in Detroit behind wide receivers Amon-Ra St. Brown and Jameson Williams, tight end Sam LaPorta, and running back Jahmyr Gibbs. Raymond should remain off the radar of fantasy managers in Week 5.

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Tampa Bay Buccaneers tight end Cade Otton was able to make a small impact during last week's loss to the Philadelphia Eagles. Otton hauled in three of his four targets for nine yards. Through four games, Otton has been held to six receptions for 34 yards and no touchdowns. He has played above 90 percent of the offensive snaps each of the last three games. Despite that, Otton doesn't appear to be a viable option in the receiving game right now. Both Emeka Egbuka and Chris Godwin figure to continue seeing a high volume of targets. Otton can continue to ride the bench until he starts making a consistent impact.

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Detroit Lions tight end Sam LaPorta has had an underwhelming season so far in terms of fantasy production, recording 16 catches for 177 yards without finding the end zone through his first four games. After earning nine targets in Week 1, LaPorta has been targeted exactly four times by Lions quarterback Jared Goff in each of the last three weeks. LaPorta has a favorable matchup on paper in Week 5 against the Cincinnati Bengals. Cincinnati has allowed the third-most passing yards (1,089) and fifth-most passing touchdowns (eight) in the league through four games. The Bengals are also allowing an average of 10 targets per game to tight ends, which is the highest mark in the league. Despite the frustrating production he has provided to this point, LaPorta remains a must-start fantasy tight end in Week 5.

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Tampa Bay Buccaneers wide receiver Sterling Shepard (foot) is ready to go for this weekend despite missing practice on Wednesday. Shepard returned to a full practice on Thursday and will be ready for the upcoming Week 5 matchup against the Seattle Seahawks. However, Shepard hasn't really done much on the field this season. He posted an 80-yard performance in Week 3, but has been quiet outside of that. The 32-year-old was held to two receptions for 14 yards last week. The assumption is that Shepard would be more involved with Mike Evans (hamstring) and Bucky Irving (foot) both sidelined. However, Emeka Egbuka and Chris Godwin both saw double digit targets last week. Possibly, Shepard sees more action this weekend, but shouldn't be viewed as anything more than a desperation option.

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Detroit Lions kicker Jake Bates knocked in both his field goal attempts and all four extra-point tries in his team's Week 4 win over the Cleveland Browns. Bates continues to lead the league in extra-point attempts and makes while playing with the high-powered Lions' offense, which is averaging 34.3 points per game through the first four weeks of the season. On paper, Detroit should be able to put up points again in Week 5 against the Cincinnati Bengals, who have allowed 29.8 points per game across their first four games. The weather in Cincinnati on Sunday also looks favorable for kicking, so Bates should be well-positioned for success in Week 5. Bates profiles as a must-start fantasy kicker this week against the Bengals.

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Tampa Bay Buccaneers wide receiver Emeka Egbuka posted his first career 100-yard game during last week's loss to the Philadelphia Eagles. The rookie wideout continued to impress as he hauled in four of his 10 targets for 101 yards and a touchdown last Sunday. The 22-year-old has stepped up and delivered especially with Mike Evans (hamstring) being absent lately. Egbuka figures to continue being a focal point in the offense for the upcoming Week 5 matchup against the Seattle Seahawks. The Bucs figure to go with a pass-heavy approach given lead back Bucky Irving (foot) has been ruled out. Egbuka might be able to surpass his season-high 10 targets pretty quick. Fantasy managers should continue plugging Egbuka into their lineups as a WR1.

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Earning at least one more start, Minnesota Vikings backup quarterback Carson Wentz carries some low-end Superflex potential this week against the Cleveland Browns. The veteran has a rough draw, however, as he'll be taking on one of the top defensive lines in football with a patchwork offensive line. Minnesota will play with backup linemen at right tackle, center, and left guard, which isn't ideal for the week in which the Vikings have to deal with Browns superstar defensive end Myles Garrett. In similar circumstances last week, though, Wentz still put up 350 passing yards and a pair of touchdowns. If the Vikings are going to have any chance to win the game, they'll likely need excellent defense and an effective passing game, the latter of which will ask Wentz to post big passing numbers.

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Baltimore Ravens quarterback Lamar Jackson (hamstring) has officially been ruled out for Sunday's matchup against the Texans. Jackson suffered a strained hamstring in Baltimore's 37-20 blowout loss last week against the Chiefs, and it's been described as a more week-to-week injury. He missed every day of practice this week, all but signaling that he will miss his first game of 2025. Jackson's last missed game due to injury came in Week 14 of the 2022 season, when he missed the Ravens' final five regular-season games and their playoff loss to the Bengals. Jackson's status will be updated again throughout next week, and it's likely that we won't see him until after Baltimore's Week 7 bye. Cooper Rush will start in his place and hopefully keep the offense operating at a competent level.

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Detroit Lions wide receiver Isaac TeSlaa has been held without a catch in each of his last two games and has just two receptions for 42 yards and a touchdown on four targets through his first four games of 2025. TeSlaa has also seen his role in the Lions offense stagnate, as he played just 20% of Detroit's offensive snaps in Week 4 and remains firmly behind Amon-Ra St. Brown, Jameson Williams, and Kalif Raymond on the team's wide receiver depth chart. TeSlaa has shown flashes of high-end potential this season, but he's currently impossible to trust as a fantasy starter.

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Tampa Bay Buccaneers wide receiver Chris Godwin put together a quiet season debut during last week's loss to the Philadelphia Eagles. Godwin made his first appearance since suffering an ugly ankle injury that ended his season mid-way through last season. The 29-year-old hauled in three of his 10 targets for 26 yards during last week's loss. It wasn't an ideal performance, but Godwin figures to continue seeing a ton of targets. The Bucs are without both Mike Evans (hamstring) and Bucky Irving (foot) for Sunday's Week 5 matchup against the Seattle Seahawks. That being said, Godwin figures to once again see a high volume this weekend. Fantasy managers in PPR formats should be able to trust him as a low-end WR2.

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Detroit Lions wide receiver Amon-Ra St. Brown has been one of the NFL's most productive pass-catchers through four weeks, recording 27 catches for 307 yards and six touchdowns on 32 targets so far this season. St. Brown should be well-positioned for success again in Week 5 in a favorable matchup on paper against the Cincinnati Bengals. Cincinnati has allowed the third-most passing yards (1,089) and fifth-most passing touchdowns (eight) in the league through four games. St. Brown profiles as a must-start fantasy wide receiver in Week 5.

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Minnesota Vikings running back Jordan Mason is facing a brutal matchup in Week 5 against the Cleveland Browns, but has enough command over his team's backfield to still be considered a low-end RB2. The Browns have allowed the fewest yards per carry of any team in the NFL, and the Vikings will meet them without three of five starters on their offensive line and a backup quarterback. But with fellow running back Aaron Jones (hamstring) still on injured reserve, Mason still should see a significant amount touches and a similar game plan to last week, in which he carried the ball 16 times and was targeted three times, catching all of them. Despite the highly unfavorable matchup, there's enough opportunity here for Mason to be considered for starting lineups.

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Tampa Bay Buccaneers running back Sean Tucker figures to see involvement in the backfield this weekend. The Bucs are going to be without Bucky Irving (foot) for this Sunday's Week 5 matchup against the Seattle Seahawks. That being said, Rachaad White will move into the lead back role with Tucker likely taking over as the backup. Through four games, Tucker has only rushed the ball once and has mainly been on special teams all season long. Tucker could be worth stashing in case Irving misses multiple weeks. However, Tucker isn't a recommended streaming option for Week 5. White will likely see a majority of the carries while the Bucs probably go with a pass-heavy approach on offense.

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Detroit Lions wide receiver Jameson Williams is off to a frustrating start to the 2025 season, recording 10 catches for 214 yards and a touchdown on 20 targets through his first four games. Williams earned a season-best eight targets in Week 4, but he dropped two passes and finished with just two catches for 40 yards. Williams remains a big-play threat, as evidenced by his league-leading average of 21.4 yards per reception. That could set him up well for success in Week 5 against the Cincinnati Bengals, who have allowed the fourth-most receptions of 20-plus yards (14) through the first four weeks of 2025. Williams is tough to trust fully, given his inconsistent production so far this season, but this may be the week for fantasy managers to take a shot at the upside and put him in their lineup. Williams profiles as a high-end WR3/flex option in Week 5 against Cincinnati.

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Detroit Lions running back Jahmyr Gibbs is off to a hot start to the 2025 season with 350 yards from scrimmage and four touchdowns on 78 total touches through his first four games of the season. Gibbs is set up well to continue that success in Week 5, when he gets a favorable matchup on paper against the Cincinnati Bengals. Cincinnati has allowed the seventh-most rushing yards and fifth-most rushing touchdowns in the NFL through four weeks. Gibbs is a lock to be a significant part of the Lions' offensive game plan, so volume of touches should not be an issue. In Week 5, Gibbs is a must-start fantasy running back across all formats.

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Following his best game in the NFL, Minnesota Vikings running back Zavier Scott is a risky RB4/Flex option heading into a matchup against the Cleveland Browns. The former Maine standout is a converted wide receiver who caught six passes and a touchdown last week, showing his fantasy appeal and making him a hot waiver commodity. Minnesota, however, has its hands full in Week 5. Three of the Vikings' five starting offensive lineman are out due to injury, and they'll play a Browns defense that leads the NFL in rushing defense with 2.7 yards per carry. Already the clear second option to starter Jordan Mason, Scott's opportunity could be diminished if the patchwork Minnesota offensive line can't hold up against Cleveland.

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Tampa Bay Buccaneers running back Rachaad White will move into the lead back role for Sunday's Week 5 matchup against the Seattle Seahawks. The Bucs will be without Bucky Irving (foot) for at least Sunday's game, but possibly longer. That being said, White will get a chance to make an impact after a slow start to the season. Through four games, White has rushed the ball 23 times for 108 yards with one touchdown while hauling in eight receptions for an additional 34 yards through the air. At times, White has shown the ability to be a capable dual-threat back. He'll get a favorable matchup against the Seattle defense this weekend. White should see enough touches to be able to provide flex value for Week 5.

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