Los Angeles Rams wide receiver Puka Nacua (foot) has returned to the lineup after previously exiting from his team's Week 6 matchup against the Baltimore Ravens, per Tom Pelissero of NFL Network. Nacua recorded two catches for 28 yards on three targets before leaving the game and will now have a chance to add to that total in the second half. Nacua has been one of the best wide receivers in the NFL so far this season, so his return to the field is a welcome sign for both the Rams and fantasy managers. Still, this foot issue for Nacua could be something to monitor coming out of Week 6.

From RotoBaller

San Francisco 49ers quarterback Mac Jones (knee, oblique) is officially active for Sunday's Week 6 contest against the Tampa Bay Buccaneers. He was listed as questionable after being a limited participant in practice. There was never much doubt about Jones' status, as it was widely expected that he would earn the start on Sunday with Brock Purdy (sidelined). Indeed, Jones is active as the Niners' primary quarterback, and he even has some fantasy appeal. The former first-round pick threw for 342 yards and two touchdowns last week, and he did so without four of the 49ers' top pass catchers. Jauan Jennings has returned to the mix this week, giving Jones another weapon. He ranks as a high-end QB2 with significant streaming appeal.

From RotoBaller

San Francisco 49ers wide receiver Jauan Jennings (ankle, rib) is officially active for Sunday's Week 6 contest against the Tampa Bay Buccaneers. He had been listed as questionable after logging back-to-back limited practices. While there was some concern about Jennings' status, he tested his injury pregame, and it was determined that he's healthy enough to play against the Bucs. His return provides a major boost to a Niners passing attack that is currently without Brandon Aiyuk (knee), George Kittle (hamstring), and Ricky Pearsall (knee). While Jennings will be catching passes from Mac Jones rather than Brock Purdy (foot), we don't expect there to be a significant fantasy drop-off. After all, Jones is averaging 302 passing yards and two passing touchdowns per start this season. Jennings is a fringe top-24 fantasy receiver this week.

From RotoBaller

Arizona Cardinals wide receiver Marvin Harrison Jr. (concussion) has officially been ruled out for the remainder of his team's Week 6 matchup against the Indianapolis Colts due to a concussion, per ESPN's Adam Schefter. Harrison Jr. recorded two catches for 32 yards on two targets before leaving the game. With Harrison Jr. sidelined, Cardinals wideouts Michael Wilson, Zay Jones, and Greg Dortch will all likely see an uptick in both playing time and target share. Arizona tight end Trey McBride could see a few extra targets go his way as well.

From RotoBaller

Arizona Cardinals running back Emari Demercado (ankle) is questionable to return to his team's Week 6 matchup against the Indianapolis Colts. Demercado had just one carry for one yard before getting injured. Even before he got hurt, it appeared that Demercado may have been behind both Michael Carter and Bam Knight in the pecking order for backfield touches in Arizona. If Demercado is unable to return, Carter and Knight would likely see all of the remaining backfield work in Week 6.

From RotoBaller

New York Jets wide receiver Garrett Wilson (knee) suffered a knee injury during his team's Week 6 matchup against the Denver Broncos in London and will undergo an MRI, according to Connor Hughes of SNY. Wilson's injury was initially reported as a hip issue, but Hughes clarifies that it is actually Wilson's knee that is the problem. Wilson recorded three catches for 13 yards on eight targets in the Jets' 13-11 loss to the Broncos. If he were to miss time, Jets wideouts Josh Reynolds, Arian Smith, and Tyler Johnson would likely see more targets, as would tight end Mason Taylor.

From RotoBaller

Arizona Cardinals wide receiver Marvin Harrison Jr. (undisclosed) has been taken to the locker room after being checked out in the blue medical tent during the first half of his team's Week 6 matchup against the Indianapolis Colts. Harrison Jr. appeared to have possibly suffered a head injury, but the exact nature of his absence has not yet been disclosed. Harrison Jr. recorded two catches for 32 yards on two targets before getting injured. If he is unable to return in Week 6, Cardinals wideouts Michael Wilson, Zay Jones, and Greg Dortch are all candidates to see an uptick in both playing time and targets.

From RotoBaller

Los Angeles Rams wide receiver Puka Nacua (foot) is questionable to return to his team's Week 6 matchup against the Baltimore Ravens due to a foot injury, per Gary Klein of the Los Angeles Times. Nacua recorded two catches for 28 yards on three targets before getting injured. If Nacua is unable to return, Rams wideout Davante Adams would likely see an uptick in targets, while fellow wide receiver Jordan Whittington would likely see significantly more playing time.

From RotoBaller

The Arizona Cardinals announced wide receiver Michael Wilson (finger) is questionable to return to Sunday's game against the Indianapolis Colts. The Cards already are beaten up on offense, as the team is playing without running backs James Conner (foot), Trey Benson (knee), and quarterback Kyler Murray (foot) in the game. If Wilson is unable to return, Arizona likely will turn to Greg Dortch and Zay Jones to work behind top receiver Marvin Harrison Jr.

From RotoBaller

Los Angeles Rams running back Blake Corum (ankle) is questionable to return to his team's Week 6 matchup against the Baltimore Ravens due to an ankle injury, per Gary Klein of the Los Angeles Times. Corum had four carries for 14 yards before getting injured. If he is unable to return, Rams RB1 Kyren Williams would likely dominate the team's backfield touches for the remainder of Week 6. Rookie running back Jarquez Hunter could potentially see the first carries of his career as well.

From RotoBaller

Denver Broncos quarterback Bo Nix completed 19 of 30 passes for 174 yards and a touchdown as the Broncos held on for a 13-11 victory against the New York Jets on Sunday in London. The second-year quarterback also added 24 rushing yards on five carries in a game thoroughly dominated by defense. Nix's overall numbers weren't remarkable, but he also didn't commit a turnover as the Denver defense held New York to just 82 total yards and recorded nine sacks. The Broncos have a favorable schedule coming up, with Nix set to take on a Dallas Cowboys defense currently ranked 32nd in net yards per attempt in Week 7.

From RotoBaller

Denver Broncos tight end Nate Adkins scored his first touchdown of the season on Sunday to help his team defeat the New York Jets 13-11 in London. The third-year tight end finished the day having caught both of his targets for 23 yards, and his 16-yard scoring connection with quarterback Bo Nix proved to be the only touchdown of the game. Even with his first touchdown in the books, Adkins has just four catches on the season. Behind fellow tight end Evan Engram, who led the team in targets on Sunday, Adkins is unlikely to receive enough volume to be considered for fantasy lineups going forward.

From RotoBaller

New York Jets wide receiver Garrett Wilson (hip) sustained an injury on Sunday during an ugly 13-11 loss to the Denver Broncos in which the Jets fell to 0-6 on the season. Jets coach Aaron Glenn confirmed the hip injury after the game, according to Antwan Staley of the New York Daily News. The former Ohio State Buckeye entered the game fourth among all wide receivers in targets and seventh in yards, but managed just three catches for 13 yards against Denver as New York threw for only 45 yards and gave up nine sacks. Wilson didn't miss extended time because of the injury on Sunday, but his status will be worth observing when the Jets return to practice prior to playing Carolina in Week 7.

From RotoBaller

Indianapolis Colts quarterback Anthony Richardson Sr. (eye) suffered an eye injury doing band work during pre-game warmups on Sunday and is inactive for the Week 6 game against the visiting Arizona Cardinals, a source told Ian Rapoport of NFL Network. It's a new low point in the former first-rounder's career after losing the starting gig to Daniel Jones to begin the 2025 season. With Richardson sidelined, rookie Riley Leonard will be forced to serve as the direct backup to Jones for Sunday's game at Lucas Oil Stadium. It's unknown at this time if Richardson will be available to back up Jones next week on the road in Los Angeles against the Chargers. Richardson has only appeared in two games so far this year and has completed one of his two pass attempts for nine yards.

From RotoBaller

Denver Broncos tight end caught five of his six targets for 42 yards during Sunday's Week 6 win over the New York Jets. He was the team's leader in targets, receptions, and receiving yards. Engram's Broncos tenure started off relatively slow, but he has come on strong lately with 13 catches, 104 yards, and one touchdown over his last three games combined. The 31-year-old will remain a low-end TE1 option heading into a relatively soft matchup against the New York Giants last week. New York most recently allowed tight end Dallas Goedert to explode for nine catches, 110 yards, and a touchdown.

From RotoBaller

New York Jets running back Breece Hall rushed for just 59 yards on 22 carries during Sunday's Week 6 loss against the Denver Broncos. He was not targeted in the passing game. While Hall set a season-high in rushing attempts and total touches, his overall production was relatively disappointing as he averaged just 2.7 yards per carry. In addition to struggling as a ball carrier, it was equally frustrating for managers to watch Hall have no role as a pass catcher. All of New York's offense struggled in the defeat, totaling a mere 82 yards as a unit. The 0-6 Jets will look to get back on track ahead of a softer matchup against the Carolina Panthers in Week 7.

From RotoBaller

Miami Dolphins running back Jaylen Wright is a healthy scratch for the second straight week on Sunday against the visiting Los Angeles Chargers at Hard Rock Stadium. Wright got off on the wrong foot in 2025 due to an injury and just hasn't been able to establish himself in Miami's backfield behind starter De'Von Achane. Although rookie Ollie Gordon II hasn't had much of a role behind Achane through five weeks, he has been the preferred chance-of-pace option over Wright, even though Wright is now healthy. The 22-year-old Wright has not played in a game yet in 2025 after carrying the ball 68 times for 249 yards in 15 games (one start) in his rookie campaign in 2024. He also caught three passes for eight yards. Fantasy managers can continue to leave Wright on the waiver wire in redraft leagues.

From RotoBaller

New England Patriots rookie wide receiver Efton Chism III is officially active and will make his NFL debut in the Week 6 game on the road against the New Orleans Saints on Sunday. Chism will be active for the first time in his career, but he's unlikely to have a big role in the Patriots' offense. Stefon Diggs, Kayshon Boutte, DeMario Douglas, and Mack Hollins are all ahead of Chism on the receiver depth chart at the moment, as is fellow rookie Kyle Williams. The 23-year-old pass-catcher had a strong preseason and training camp, but it's unlikely that he's going to have a big role in New England's offense when all is said and done in 2025. For now, Chism is merely a bench stash in dynasty/keeper leagues.

From RotoBaller

Indianapolis Colts wide receiver Adonai Mitchell is a healthy scratch for the team's Week 6 contest on Sunday against the visiting Arizona Cardinals at Lucas Oil Stadium. With Alec Pierce (concussion) returning after a two-game absence, Mitchell will be the odd man out in Indy's receiving corps. The 23-year-old is firmly in head coach Shane Steichen's doghouse after two big blunders in the Week 4 loss to the Los Angeles Rams that cost the team the game. Mitchell dropped the football just before crossing the goal line in what would have been a long touchdown catch, and then he was called for holding on a big running play that would have gone for a touchdown. After that rough Week 4, Mitchell has fallen down the receiving depth chart for the Colts and is currently behind Michael Pittman Jr., Josh Downs, Pierce, and Ashton Dulin.

From RotoBaller

New England Patriots cornerback Christian Gonzalez (hamstring) is officially active for the Week 6 game on the road in New Orleans against the Saints on Sunday. Gonzalez will play despite being listed as questionable on Friday's final injury report. The Patriots will also have linebacker Marte Mapu (hamstring, neck), defensive tackle Milton Williams (ankle, illness), and cornerback Charles Woods (knee) are all active after being listed as questionable coming into Sunday's game. The 23-year-old Gonzalez missed the first three weeks of the season with a hamstring injury, so it will be something to watch for in Sunday's game. The former first-rounder's presence in New England's secondary will make life more difficult for quarterback Spencer Rattler and the Saints' offense. The Pats' defense/special teams unit should be a popular streamer this weekend.

From RotoBaller